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H OY ™]OMLA fh fb y heer bivkgnthes Hexmene, Hermenes ore thas Chearpieal S eeated by the boty to combo & regulate the octet, of. O certain cells y Clergams. Shetal atdinofs L/n on enclorrime atontts these beymones- Sherefone hakinone _ oma be cfefimnedf os te spebifee Prookuct a of ( emcloviby glomols secreted U inten - he [heoof & cameos! _ boockey Ee to fort ie proliucws a kefinite 6 feng ateatl felt, g man be exettaler ev | inkh betors. I b hesvomone | uw a henntel g OLS as a Chameeal —metangey b/w _ frocucey & target. é te body Y of | SeeveXRe Ons ‘ Maintaining homeoSa sts voquines v tle Coorotinatiion Wtf ore Mem & pibetion bes oly Mw im OVGOANS + bering eels Jy Cissueds Oley ports of through these te) veers | ( Chemicals ( horeabenexe\: Charactertstics of hevmones. he hormones 0) foes spectiec foltowt brofertios bees ee Net Wey | ( ot emaloerine fete 7). [hex Vane trom da the Longer ( through utation, — itt) | Sleby lane CE Scanned with OKEN Scanner ‘o] = vil | Thor ane destroyer after thety _—_aekion. _ . vii) (a Cant, be stoves n _ fa i Wine : aT ane. ee, fe) wbrelh et ne . (/ fe 2 _ ix) hex blow action ents a | — herakione, - 7 Com plex ; | i o a 4 3 Chemical — of lioy: mones | —- A anh theyre lowe, aman ee 2 ffovert, as hormones im thy buurmam, bool i ay ae Cam be hivieded imo % - uA b axed 5 oy theo chemical - Dp, (a > 1 ) Lifie Adevived boveno nes. am 4). Dab eno - aciof dertveop hevmones. > 3) Peptide hormones: >" ! y- 5 Lepécd fertved hormones : Petes ave _ertved ©) _ Sade Cholesterol, & thus ret alty a) | ston haw to it She préimnare, “as en _—¢_ oe pid ——_hovemones im bacrmallys a steno? bormones. Chemically these, bovmones ) Ove wserolhig eetones or ( ateetots thet ix ) why thls Chemical mame wit em in > “ot tow OLLOboL S Yfene’ dew Retomnes. - en Estradiol» _Testosterene _, ] Allorstervone , 2) Cortisol 0 Stervotd hovmones ane, imsoluble in water ce gy they Ore, tronsported bey transport — sa protelnst Pag) blood, .. las a Ove sett > remain in eeukation for Lemaen time = pas Thus banime longer batt | Life ( thar od fated ener U - _ a CE Scanned with OKEN Scanner fife Clasifivation of bevmrones : ~Jssee \) Heyenones | ane chastedied into $5 catesertes on the has | of ( 1 a - - - gy (4) Chemical nature + _ Basecf om chemical oO! mature hormones owe ehartidied — ar: Oo a) Steroid bermenes These ave| made ww ee cepddls one Loscoall devived from oi chbLestorol oa Tetostermell 2 Extrogen_, | ete 2) 5 L > J a Amine —_ beremones: hese ave made . of ae Amines: Amine hormones ane derive? » drem ! ¢ a) HL amino acid Ceposine evel Ts, Ta, efinefinine ; revefineferie: c), Pop tide hexmnomes: These, beramones ane, fo made uf of dow amino aed _reredues. 2) ex Ong . INDY. ote Fo aoa residues ) od _ om A).| ProCetn _bevmone: These _ hormones one made a of a) chain of amino acids . She, yepreremnf 7° Y 9°, 3° 4 Yo | structure of _protoby,. - ex | Insulin a Sensotrapisd —- oo e). Lbs, eoprotein bexmone. These ane “conjugate? i Hotelims were cambouplrates 9 (| Lamnome, | galactose , fucose oth ane attached . (lew tu, Fou, Tsu. GIB Py gab og Eccosomotd bereene: ~ She 2écosamot AS are eH fomath _ fatty acid oferdvatives — Ea Vanity of __ enathilonic acid (Cao). x Prostagtontins. _ | aie CE Scanned with OKEN Scanner — | Mode _ of action ; oie | Lrroup Lo hormones + — hese. hormones bein to imtracelluloy rece ftovs to tere hermone receptor __combten | tyrouah, | % thely biochemical _|dumetions Vane meditate? Share, heronones ane Lifofhétlic 2) nakeure & ave Aerdvatines - lod Cholesterol ( t Ts ¥ Ty). hey lane foeumel nadie im adoctation (oz Cromsport brotiims — ¥ posers velotiy aii tengey beef ives lex, Extrogen py eR en . a ‘ 4 one. | er 6). Group ae KH emeludes those bovenohes & bind to cele kev face rece ftov3 g stimutote he yelease of } cortacah moleuntes ff 4" mesemmers | & on tun for fovon the biochemical, ( funtion _ These | lol mones ane cpophobte tn mature & ane Eee frets | Crreugsut creutation . Nature» of action » a\ local ley: MONE 4 are those horveenes C hove oof ecifec Locak, edlects throug, _ farac- Caime Useeretions ex! Testosterond, | b). | Rrenervat,. hormones: These hevemoneS ave tramsported bey esetlation to te dixtaly target! Cosel / organ. ew Insulem , “thyroid? holnom / i" & ete | Effect they produce: i ia — CE Scanned with OKEN Scanner Pi) | Gocub 7 — I ALthoug, ade Lode Chet - thw howmno%e otepemds | ¢ ( Vee 0 Ro okondting oo 8 receptor 4 a i activation af : aitfednt proteingy but thaty frémany | i= motel oy Level have been Saded in ) mutch Petail. Many _lrowmmones ee , imetucess ov vere in gen é controtted begntheris of con tral are cellat- i} aw emreyrmeds\ Grok rT bermonesd enclucle, hare i hovenones ¢ bind to intracellular vece- fters . hese bewmoneds are tébobhtttee im | mative & can eConcly fas | | throug os ae Shag ¢g act! thro g tle a locatef other én ey ial the UelEnrs of the “Sovotd — at, mosh, toey Changing the tramsexthtional vate ( of g apelec le genes im | mueleox DNA + Toe steroid Crermeme bas - _ spect fic cellular OlLigomerte receptor froteim | im poset oy mutes. Tis | binds about, lhe Compo mational __ Chomae Vs abso chamae im the Kunfoce v Change of the ( veeebtov protein Um tondln —sdtex ——sbimeting «IE te mueleon | ebwematio 4 binds tthe Atoyod necting acceptor site bef aw clement ( YRE). HRE és | Hevmone. | BEN: CE Scanned with OKEN Scanner Present én DNA —_stwamel eéale. ot a promoten site oy Q a Mpecific I Aterotof responsive gene. the 3 ; ] ae Henge im! inty ulon —_ Cence- 5 negli _ A ALES the vate en structure entymatie > yhex ex 7s protein Cocteot’ | ; et a fer gent. Sesées| FSU im 5 ulkimarte, eohulay effects: hu veeefitow ey Atertoo Comb lave ( psc)! Aubsequartly I teoves | tee acceptor! nite asta © fvell vecohtry & tow! steroid hevmone. In i re > vequlate, thy tromseniption , seme steroid? me omnaey ALSO fact. as Tequlatora 4 agent, toy ¢ fost, 7 Craornent pete. U fro Aone g ! tromiyports Fi Heer =o > 3 ) = ae ES - Stewid 7 > Heeb atm = see Vegi x [ob J \ 3 [ SRC L \ \. 5 a : i fer doy | ass ee ee ey 2 | \ [rromenip tion f-——f Necfenrs ) | mea | a ner \ ae: f > ye es ; S a ji4 ye ) CE Scanned with OKEN Scanner —/— !-— ie) 2 She hevmones _UhRe alucaaen , cation — Sf amines @ PT ere VV ees ty 7 influencing he Chamger in emthaeotlulay> cAMP ( Coneemtwativer Unough aclenylate ai eegelore Kem, ~ he hase bimels 4 oo 0 Mpeetfec vece ftox fresemt, at the ao —— satel 4 cell Neer brvoner Deven 5 Ae x eco ftovs ane II fresemt yD. yl me receptors yerrlain assoctathd -) z either ice Oa hatin a Min uLotory ox G Soterm 2 ( 4 are | sa pasar rr ee o Cifees atehem atemt,\) a feubumits fren, ra \ y T ott pond) te (8 oe én Fern ation of Je . how safe soit fromotes | ww > himdinea fs erp to I om - | sea emit y; > et endy U As ox Ge. when ATP hime? y plas z Aimeutatory hubumntt, fe, XsGTP , ths | xs subumit Vw thon released = & iF ) hémets te ademutate eqtane —- & os 2 frresemt, o™ Ouminat 9 ide of eet a lmerndyome. _ Shes bimcing d. lOk- Kecbumets a ademytate _agtase Ni bvinds) — ahout’ y combprmatiomnal ———Senamae tn VY actematate cpLane te actiuclte of 4 us active | ai ademnntate Cyclase Cause, th Conversion y at? ents UT cAmP. cAMP tun activated tia ——simactive Protein Kraze ph ; causing aivsoctation of. e perch eumbts focm 2. Veneacgeiet sais. 7 Y CE Scanned with OKEN Scanner Poteon -(RJe] [4 () oO oc | po Pooaphory tation of Bivebeméical —— prebceins at Shrine vespse {cascade Shreoine _ | Lihe cAMP, __ foty-prosphoémostot _@ DAY ( diacnk alert ) | Claes an. 2° eremengeys. Suey V avel! found as ge mesenger C im valepressin , Tey, GoRy ete. Shbke —_hovemores actilete —__pliosphotéfose _C protfriryostle pee te frets huyls care cxtfrotete (9Ps)._ : (ee a, | im — ea Tew OC freecion ( fr eet — | a CE Scanned with OKEN Scanner ————_—____] » ——— |_ Btosagntneses Catecholamimes (_ achenal im» 4 hevmon es}. pene medulla ix histologically made of _etoemeddén __eettdt _U Fouse Ces whe Cu hovrcndones epimepbxrtne & ner ses : a ese, hermones | One fofutante | &fy os em ebygen hermones , _ltecey C hey ane froctucbif im reshenke q feta I ‘Hint. tease @ "feat ane Ud also hn O¢ aw eatechha- onine, line ® the/ presence of __eluyolro- rey lated flemeye vim. | Choemoffiin leotes Ccontiabn offim d ayamules il & one vespomehte fr | eV vetense dh. —_actronal zat utl oot | hovrnomes . wnolex ae action ‘ef O" empathetic nervous teary | (S t > | Plosynttescs Piosynttescs df. catecholamenes Envoewe feteuiing Atob | Converséon fremyolomine ts __teposine . catecholamines | Vane — ctoréved — from thw amino acd premylatlamine , & acts | AB a freeuriser- In PU ene Liver firemgtokomine & bi lror,Loted poumytatomine eerowstore emfme q emto ( tepodene! arnt Lem actly os on mediate \ treeursox of TT pateetnntamimes Evem te ever! tase — | OhEME mnolecle’ reach to the Cnemaffin TO ete via ctteulation » | : CE Scanned with OKEN Scanner SS QD he CH= con ( Phengtatarr ine) NUS _ eo |_PhemutoLamene _ oa | idlerstase 2 J =) sare an frye aa ye » o HOR Pa or (Tyrosine ) > nus “ 9 <- ae 3 ol ji) | Formation of DOPA fom teponime 5 y woKEme, Uen chvermoffion cetth ix 2 Cenv: tmto = dlilugolreuypirenytalomine ( DoPA) & he em & V tepdltine V byctroetose. > shes reaction! ts ad ste 9 Leobliting s) yeartion a the actévity df. tepoklne @) bagohy Z “ resutoted em Va (antes, _ Uf wows » Shyiodbme byl e ths ; imbihited a, Va Kenic’ ( \\ yvotime 2) derivatives ( eneliding, X- wae Cpe ») Tie 2 2) = ~N i Kanon 5 nom| ff. 2 ci WO : 3 a CHa — t= coo™ vT hg = tom — - OF Oo CE Scanned with OKEN Scanner fa eM mE yo etham me ne —_|rmethyt transferase | (PNT). — Sheredere , mont fess \) % ty {2 amend, whereas oho ome is N- mrethagkateel g°— amene ae o= 5 Nenef oe Plane a a S) pp adenosy’ onetitemine, Phemylethamolamine N- 7m ~~ * Y Cromsfonaze. ( PNMITY. oa S-adenone hemoeystetne °° ¢ q - 5 ee y ; see i E OQ ae | epimepiwine J = 4o Td —- ou o) .- nie os 5 CE Scanned with OKEN Scanner | a on _ 3 2 ee ws | Cribedithipenthg oe ool tin bos iki, Wthinvaiebs om ne —_| ter —— ee ——_ ' ela | (tae) aotseed the Sih pen co — rae & named [eas Fr & aon - >) | Spneneses : | OU Ty ey sone intimated aortas op Gmino acief teposine Share. hormones one | pene Cina the fitewing steps : i). robbing of tockide 7 Ti GY Jocing| & exsembrol foy the hun Weses ud ese hewmone » | Peve aay tat fi rw NV bot s loctine coment us fouyeh ad] all epwid glomed. She uptoke ! mi ef lodide tg q truiollp ahamo? locewvh UD) agaimest, tue G comeot vation d ova. dom, a Vi an enenay vequising Ubvoems & i tinted & WW ptphee | | topenclor® Nat- kt pump » This Not dumb on this cade | és hin. as | teptcte, furrh. She iooticfe, pump dotttextan ees ow | theta | [ ltostige is comtvotted 7 | Tsu. U a) | Qxtolation of __leolicle _ She conven dion h inclife, into CE Scanned with OKEN Scanner !¥).| Coufeing of kocoteposines , ' withlem | tw Y Usproglohutin molecules tex OTs oxida tbl ell, coupe = Onvthoy DIT Yesidue wo (/ oven! Ta oy DY és oxicatively couples | & may to fern Tp: I Seis coupling is. mectio.toct ba tas emeyme | terrcforodluce §_ during UU couftirg JT am old mine mmoleute (ix teredked. Uptahe & proteolysis of tUuproglobulon + [| Shpoig st fete «cous astate cottoid fem | de Lumen Dnoudy, the oe of. pin tosis : ese by wprets an ) combene “d _e ims She _| becnetion ——_ wntalm proteases , tet eel e tepals clases & wai pridases. wyoly Lotarlin cr ott = n al ° 097 ye “bt Ta - Ty fadses to the bevod hey faite | Lif eesion heroug Ukletor membrome MIT & nay relLeaded umedergoes deindkination : Suis deinclimation ts | caused by rnitcrodomal __ermyme__ ekocktnanser_ She. — Uheroltedt lodime, is" reese fo the toctimartion of teproseme yersiduer. | CE Scanned with OKEN Scanner [fey y ___| (78 pa) g Kevin atbumin. whereas Tr oO pe &s transported z fue | C84) mnt Seog nef Piag a AD — — huproperontalose © 7 i ~\ y J J YT > aN = GH Cony tan — tt: Cooy 2) Cg Clty 5 A cs a — r A ae ou OR Yy maT) (DoT) aa a a 7) oe han CH ~ Coo han! CH= Ceoy Han CH~ Covi =| CMS, i Ake _ _ wh =< T ne ou HIT i VPAOMAORE, Cis i aN Re i ibaa A 9 x 4A + J rAAr - ty 7 etemine DIF [tn pane | Py 3 Hy / I-YX\2z S) oy 5 ©) (Ta). CE Scanned with OKEN Scanner 
