Hypertension Medications โ Study Sheet
RAAS
- โ BP
โ โ BP flow to kidneys
โ renin
- angiotensinogen โ angiotensin 1
- lungs โ ACE (angiotensin converting enzyme)
- angiotensin 1 โ angiotensin 2
- vasoconstriction
- works on adrenal gland
โ produces aldosterone
โ works on kidney
โ โ reabsorption of Naโ
โ โ water reabsorption
โ โ blood volume โ increase BP
ACE Inhibitors (end in -pril)
- lisinopril, captopril, enalapril, benazepril
How they work:
- stop vasoconstriction
- stop increase blood volume
- decrease preload
- decrease afterload
- increase cardiac output
Side effects:
- hypotension
- cough โ normally goes away in weeks
- increase potassium (hyperkalemia)
- rash โ angioedema
Indications:
- hypertension
- CHF โ life savers
- diabetic nephropathy
- post MI ventricular dysfunction
