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Immune response overview diagram, Schemes and Mind Maps of Immunology

Typology: Schemes and Mind Maps

2020/2021

Uploaded on 06/11/2021

johnatan
johnatan 🇺🇸

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280 documents

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Download Immune response overview diagram and more Schemes and Mind Maps Immunology in PDF only on Docsity! innate immunity 0-4hrs inflammation 4-96hrs MBL CH �► -Q- complement activation -Q- inflammatory response (C3a, C4a, CSa) opsonisation of pathogens (C3b, C4b) MAC complex pathogen lysis (C5b-C9) TLR I I I I I I I I I I MHC Il PAMP PRR NF-KB activation ii costimulatory molecules e.g. B7 proinflammatory cytokine release IL-1 IL-6 IL-8 IL-12 TNFa ii CRP fever m1cro- coagulation to prevent spread of infection increased capillary permeability ➔ oedema and swelling chemotaxis utrophil B7 I I I I I I I I I I I I MHC MHC Il !*@! 4-IBBL B7 infected I cell synapse formation (cells touch) perforin, granzymes, granulysin ):� induction of apoptosis )� p CD40 IFN-y cell-mediated immunity TH1 ----------· TCR CD40 +++ MHC Il humoral immunity TH2 I L-2 IL-4 I L-5 A y-< - neutralise toxins opsonise pathogens .,.- antibodies � -< "- 1"""' activate complement lgM ➔ lgG lgA lgE � A activate effector cells