LAB 7 Stereochemistry (CHE-250 Organic chem I) S26, Georgia military college, Lab Reports of Organic Chemistry

It is completely solved worksheet of Lab 7 titled Stereochemistry In this, questions relayed stereochemistry of compounds are answered Course: Organic chemistry I CHE-250 Georgia military College

Typology: Lab Reports

2025/2026

Available from 06/17/2026

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Name: _________________________________________________ Date: ______________
CHE-250 Organic Chemistry I
Laboratory 7: Stereochemistry I
Background:
In this lab you will understand stereochemistry concepts including chirality, enantiomers,
diastereomers, meso compounds, and conformational isomerism using molecular models or
visualization software.
There are a few objectives of this lab:
1. Recognizing charity centers.
2. Assign R/S configurations.
3. Summarizing stereoisomers and relationships
Materials:
1. Pen and paper
2. Molecular modeling kit
3. Optional: Free for Students Organic chemistry drawing software
Lab Report Requirements:
When needed use complete sentences to answer questions or describe the procedures. Show
your work.
You can use pen and paper for your drawings, and molecular modeling kit to visualize molecules,
or you can use free chemistry drawing software to complete this lab report.
Sign your name on each page, scan and upload them to Canvas. Make sure to save changes made
to your lab report before submission.
Lab Report:
Upload pictures of your models and drawings to this lab report.
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Name: _________________________________________________ Date: ______________ CHE-250 Organic Chemistry I

Laboratory 7: Stereochemistry I

Background:

In this lab you will understand stereochemistry concepts including chirality, enantiomers, diastereomers, meso compounds, and conformational isomerism using molecular models or visualization software. There are a few objectives of this lab:

  1. Recognizing charity centers.
  2. Assign R/S configurations.
  3. Summarizing stereoisomers and relationships Materials:
  4. Pen and paper
  5. Molecular modeling kit
  6. Optional: Free for Students Organic chemistry drawing software Lab Report Requirements: When needed use complete sentences to answer questions or describe the procedures. Show your work. You can use pen and paper for your drawings, and molecular modeling kit to visualize molecules, or you can use free chemistry drawing software to complete this lab report. Sign your name on each page, scan and upload them to Canvas. Make sure to save changes made to your lab report before submission. Lab Report: Upload pictures of your models and drawings to this lab report.

Part 1: Chirality and Enantiomers: Build and draw a tetrahedral carbon atom that is bonded to four different substituents (e.g., CHBrClF). Construct a mirror image of the molecule. Compare the original and the mirror image: Try to superimpose them using the model or software. Determine if the pair are enantiomers (non-superimposable mirror images). Record your findings, including 3D structures and superimposability results. Upload pictures of your models and drawings to this lab report. Yes, these pairs are enantiomers as they are non-super imposable on each other. Part 2: Identifying Chiral Centers Draw or model structures of the following molecules: 1,2-dimethylcyclopentane 3 - ethyl-2,2,4-trimethylpentane 1 - bromo- 1 - chloropropane Identify all chirality centers. Assign R/S configurations to each chiral center using the Cahn-Ingold-Prelog priority rules. Upload pictures of your models and drawings to this lab report.

Diastereomer pairs: (A,C) (A,D) (B,C) (B,D) No there are no meso compounds as both substituents are different. Part 4: Conformational Analysis Build or draw butane. Rotate around single bonds (e.g., C2–C3 in butane) and identify staggered and eclipsed conformations. Draw energy diagrams to show relative stability. Upload pictures of your models and drawings to this lab report.

Conclusion questions:

- How do enantiomers differ in physical and chemical properties? Enantiomers have same physical and chemical properties. They only differ in rotation of plane polarized light that passes through them. - Why are meso compounds achiral? Due to presence of symmetry, the optical rotations cancel out each other. Due to internal compensation of optical rotation, the overall molecule becomes achiral. - Which conformations are most stable and why? The most stable conformation is anti-periplanar. This staggered conformation has least steric hinderance and minimal torsional strain. Highest instability is present in fully eclipsed conformation as they have highest steric hindrance and torsional strain. Stability: Anti> Gauche > eclipsed