Lecture notes in medical surgical nursing, Lecture notes of Nursing

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2020/2021

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MEDICAL SURGICAL NURSING 2 DENN HILL RIOROSO
1
“ENDOCRINE DISORDERS”
HYPERPITUITARISM
Hyperplasia of pituitary tissue
Prolactinomas account for 60-80% of all pituitary
hormones
Bitemporal Hemianopia because of compressed Optic
nerve due to increased size of prolactin
Homogenous hemianopia (kalahati lang nakikita sa
isang side ng mata)
ASSESSMENT:
Over production of growth hormone
Neurologic Manifestation
Hemianopia
Scotomas or blindness
Somnolence due to pressure
Increased ICP
Behavioral changes, seizure
Disturbance in appetite, sleep, temperature
Endocrine manifestation
Oligomenorrhea, amenorrhea
Infertility
Dyspareunia (pain during sex)
Decreased libido and impotence
Galactorrhea
MANAGEMENT:
Transsphenoidal Hypophysectomy
o Keep head elevated for 2 weeks due to increased
ICP
o Maintain nasal packing due to increased secretion
o Provide oral care
o Instruct to avoid blowing nose that increase ICP
o Monitor for postnasal drip, it may indicate CSF
o Report urine spG is below 1.004 indicated DI
o Normal urine spG 1.010-1.030
o Administer glucocorticoids to compensate don sa
tinanggal
o CARDINAL SIGN OF INCREASED ICP =
Hyperthermia, hypertension, bradycardia,
bradypnea, headache, wide pulse pressure
Radiation therapy
Parlodel to lower GH and prolactin levels
HYPOPITUITARISM
Simmonds’s Disease total absence of all pituitary
hormones
Sheehan’s Syndrome cause by post-partum pituitary
necrosis
CAUSES:
Tumors
Trauma
Encephalitis
Autoimmunity
Stroke
Surgery
Radiation of pituitary gland
ASSESSMENT:
Mild to moderate obesity
Infertility
Fatigue,
Hypotension
Hemianopsia
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“ENDOCRINE DISORDERS”

HYPERPITUITARISM

  • Hyperplasia of pituitary tissue
  • Prolactinomas account for 60-80% of all pituitary hormones
  • Bitemporal Hemianopia because of compressed Optic nerve due to increased size of prolactin
  • Homogenous hemianopia (kalahati lang nakikita sa isang side ng mata) ASSESSMENT: ✓ Over production of growth hormone ✓ Neurologic Manifestation ✓ Hemianopia ✓ Scotomas or blindness ✓ Somnolence due to pressure ✓ Increased ICP ✓ Behavioral changes, seizure ✓ Disturbance in appetite, sleep, temperature ✓ Endocrine manifestation ✓ Oligomenorrhea, amenorrhea ✓ Infertility ✓ Dyspareunia (pain during sex) ✓ Decreased libido and impotence ✓ Galactorrhea MANAGEMENT: ▪ Transsphenoidal Hypophysectomy o Keep head elevated for 2 weeks due to increased ICP o Maintain nasal packing due to increased secretion o Provide oral care o Instruct to avoid blowing nose that increase ICP o Monitor for postnasal drip, it may indicate CSF o Report urine spG is below 1.004 indicated DI o Normal urine spG 1.010-1. o Administer glucocorticoids – to compensate don sa tinanggal o CARDINAL SIGN OF INCREASED ICP = Hyperthermia, hypertension, bradycardia, bradypnea, headache, wide pulse pressure ▪ Radiation therapy ▪ Parlodel to lower GH and prolactin levels HYPOPITUITARISM
  • Simmonds’s Disease – total absence of all pituitary hormones
  • Sheehan’s Syndrome – cause by post-partum pituitary necrosis CAUSES:  Tumors  Trauma  Encephalitis  Autoimmunity  Stroke  Surgery  Radiation of pituitary gland ASSESSMENT: ✓ Mild to moderate obesity ✓ Infertility ✓ Fatigue, ✓ Hypotension ✓ Hemianopsia

✓ Headache o Due to tumors of pituitary gland that compresses optic nerve MANAGEMENT: ▪ Surgical removal ▪ Radiation therapy ▪ Hormonal replacement therapy

“COMPLICATIONS OF THYROIDISM”

THYROID STORM

  • It is a life-threatening condition occurs in a patient with uncontrollable hyperthyroidism. ASSESSMENT: ✓ Fever ✓ Agitation, tremors, anxiety ✓ Delirium ✓ Coma MANAGEMENT: ▪ Maintain patent airway and adequate ventilation. ▪ Administer antithyroid medications, iodides, propranolol, and glucocorticoids as prescribed ▪ Administer nonsalicylate antipyretics as prescribed. o Salicylates increase free thyroid hormone levels ▪ Use a cooling blanket to decrease temperature MYXEDEMA COMA
  • This rare but serious disorder results from persistently low thyroid production or hypothyroidism****. ASSESSMENT: ✓ Hyponatremia ✓ Hypoglycemia ✓ Generalized edema ✓ Coma ✓ Hypothermia MANAGEMENT: ▪ Institute aspiration precautions ▪ Administer normal or hypertonic saline as prescribed ▪ Administer levothyroxine sodium IV as prescribed ▪ Administer glucose IV as prescribed ▪ Keep the patient warm ▪ Monitor for changes in mental status ▪ Assess electrolyte and glucose levels

THYROIDECTOMY

  • Removal of the thyroid gland
  • Performed when persistent hyperthyroidism exists PREOP: ❖ Obtain vital signs and weight. ❖ Assess electrolyte and glucose levels. ❖ Instruct the patient in how to perform coughing and DBE and how to support the neck in the postop period when coughing and moving. ❖ Administer antithyroid meds, iodides, propranolol, and glucocorticoids.

HBA1C – Glycated hemoglobin test – measures hemoglobin to obtain 3 months’ span of RBC; the attachment of blood glucose to hemoglobin in RBC o Your compliance will be detected o NV > 6.0% ➢ Urine test – (+) glycosuria o (+) ketonemia – Abnormal increase of ketones in the body – TYPE 1 DIABETES ONLY (Diabetic ketoacidosis) o Develops in response to decreased insulin; the brain will use ketones as an alternative MANAGEMENT: ▪ Controlling the amount of food intake helps the regulation of glucose level ▪ Weight the patient time to time ▪ Encourage the patient to have engage in exercising to improve circulation and muscle tone and also to decrease glucose, cholesterol, and triglyceride levels. ▪ Instruct the patient with DM to monitor the blood glucose level before, during, and after exercising. ▪ Administer oral hypoglycemic medications. ▪ Transplantation of pancreas ▪ Ensure adequate food intake ▪ Scrupulous foot care ▪ Eat extra food before periods of vigorous exercise ▪ X high knee stockings ▪ Consult physician when removing corns from feet ▪ X barefoot ▪ X alcohol – may increase hypoglycemia ▪ Store insulin at room temp. other medications in fridge / cool areas ▪ X injecting cold insulin – tissue reaction may occur ▪ Rotate injection site – to avoid lipodystrophy (localized disturbance of fats) ▪ Wear ID/bracelet ▪ Always have something to eat (sugar) in your bag

Oral hypoglycemic agents | ANTIDIABETIC AGENTS (TYPE

2 DM)

a. Sulfonylureas – stimulates insulin pancreas

o Glyburide

o Diabinase

o Glipizide

b. Biguanides – facilitates insulin reaction; making the insulin

less resistant at receptor site (TYPE 2)

o Metformin

▪ Adverse effect: lactic acidosis

c. Alpha Glucosidase Inhibitors – delays absorption of

glucose

o Dearbose

o Precose

d. Thiazolidinediones – enhances insulin but not increasing

insulin secretion from beta cell; acts with the existing

insulin by enhancing its action

o Rosiglitazone

o Piaglitazone

e. Miglitinides – stimulates release of insulin from pancreatic

cells

What to infuse? – D5 0 - 50 (hypertonic) = FAST DRIP

▪ Miracle drug

▪ Has higher concentration of sugar

▪ Usually given to px in coma due to diabetes

Note: when storing insulin pen in the refrigerator, it

should be placed horizontally to balance the concentration

If in vial, roll insulin vial to mix, do not shake,

remove air bubbles in the syringe

Press site after injection; DO NOT RUB – rubbing

may alter the rate of insulin absorption

To make insulin more absorbed in the SQ, and all

medications are injected, count 1-10 during

administration

Avoid smoking for 30 mins after injection

✓ Serum Na, K decreased o due to osmotic diuresis which leads to volume depletion o Administer sodium chloride MANAGEMENT: ▪ Treat dehydration with rapid IV infusions of 0.9% or 0.45% NS as prescribed; dextrose is added to IV fluids when the blood glucose level reaches 250 to 300 mg/dL ▪ Monitor potassium level closely o Dehydration and acidosis, the serum potassium level will decrease, and potassium replacement is required. ▪ Cardiac monitoring o Due to risks associated with abnormal serum potassium levels. HYPERGLYCEMIC HYPEROSMOLAR NON KETONIC SYNDROME

  • Extreme hyperglycemia occurs without ketosis or acidosis o Ketosis and acidosis do not occur because there is an enough insulin to prevent breakdown of fats for energy.
  • 800 - 1000 mg/dl
  • Hyperglycemia => osmotic diuresis => hyperosmolarity => pure hyperosmolar state => loss of electrolytes => cellular dehydration => volume depletion => impaired renal function Complications of DM:  Degenerative changes in the vascular system  Neuropathy  Diabetic retinopathy  Cataract MANAGEMENT: ▪ Same with DKA ▪ Fluid replacement ▪ Rehydration alone may decrease glucose levels