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LIVER TUMORS IMPORTANT NOTES, Study Guides, Projects, Research of Medical Sciences

King George's Medical UniversityMedical Sciences

Also called hepatocellular carcinoma, this is the most common form of primary liver cancer. Chronic infection with hepatitis B and C increases the risk of developing this type of cancer. Other causes include certain chemicals, alcoholism, and chronic liver cirrhosis.

Typology: Study Guides, Projects, Research

2022/2023

Available from 02/10/2023

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LIVER TUMOURS A) Benign: Haemangioma(commonest), Liver cell adenoma, and focol nodular hyperplasia. B) Malignant: I) Primary: a. Hepatocytes + Hepatocellular carciroma ( HCC). b. Bile ducts — cholangiocarcinoma. c. Mixed > cholangiohepatoma. d. Hepatoblastoma : HCC occur in children , its cells similar to fetal liver cells . IT) Secondary. * Primary Malignant Tumours * Hepatocellular carcinoma(HCC) Cholangiocarcinoma Incidence: “+ More in old males. The commonest malignancy in Egypt nowadays . 80% of primary malignant liver tumors . = 10 % of primary malignant liver tumors. Predisposing factors: 1. Infection with Hepatitis B & C viruses =Prolonged infection results in integration of viral DNA into host genome, thus starting malignant changes . 2. Liver cirrhosis especially post- hepatitic or alcoholic cirrhosis . " 90% of HCC are carriers of hepatitis B or C viruses or have cirrhosis . 1. Clonorichis sinensis infestations causing cholangitis . 2. Haemochromatosis. 3. Congenital poly cystic liver. 4. Selerosing cholangitis. 5. Choledochal cyst.