medical doses chapter 3 and 4, Exercises of Pharmacy

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UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS SCHOOL OF PHARMACY FARM 7166 2018 - 2019 MATHEMATICS FUNDAMENTALS

Calculations involving Drug

Doses

R. Garcia MPH BSPh BBA

General Concepts Review:

Dose:

quantity of a drug needed to

obtain a given effect-it

depends on physico-

chemical, biochemical and

pharmacological factors

when the dose is said to follow a normal distribution the normal distribution rules applies:

Using these estimates as

reference,various types of

calculations might be

required

Dose delivery:

Routes of Administration

v.s.

Dosage Forms

See Ansel 13 th , pp. 106

Dose delivery:

don’t forget

the tsp

dichotomy….

1. If the dose of a drug is 80 mg, how

many doses will be contained in 0.5 g?

de Ansel,H.: Pharmaceutical Calculations Pharmacist Handbook

2. What would be the size of each dose if

a patient is to take the contents of a 8 fl

oz bottle in ten divided doses?

de Ansel,H.: Pharmaceutical Calculations Pharmacist Handbook

4. A patient is to receive a total daily dose

of 500 mg given in divided doses q.i.d.

What is the size of each dose?

de Ansel,H.: Pharmaceutical Calculations Pharmacist Handbook

5. If you need 30 (60, 90) doses of a

certain drug, how much drug will you

need if the dose is 250 mg?

de Ansel,H.: Pharmaceutical Calculations Pharmacist Handbook

7. How much of a solution would you need

to dispense if the directions to the

patient are “ii gtts q6h x 4 d”?(Assume a

calibration of 2.5 gtts/ml)

de Ansel,H.: Pharmaceutical Calculations Pharmacist Handbook

8. If 750 mg of drug are used to prepare

90 ml of a syrup, how much drug is

contained in each teaspoonful dose?

de Ansel,H.: Pharmaceutical Calculations Pharmacist Handbook

10. How many milligrams of DM and of

NH

4

Cl will be contained in each dose of

the following prescription?

de Ansel,H.: Pharmaceutical Calculations Pharmacist Handbook

R

D.M. 0.6g NH 4 Cl 6 g Cherry Syrup ad 4 fl oz

Sig i qid for cough

11. A certain compounded prescription calls

for 10 mg of drug in each tsp. How

much drug is required to prepare 1 pt of

this liquid?

de Ansel,H.: Pharmaceutical Calculations Pharmacist Handbook