Module 1 – Cells and Cell Processes, Lecture notes of Biology

Module 1 – Cells and Cell Processes. Unit 1a: Introduction to Life. BIO. ... Every topic covered in biology class is related to one of the characteristics ...

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Meyers High School Mr.
Moules
Keystone Exam Review Sheet Biology
Module 1 Cells and Cell Processes
Unit 1a: Introduction to Life BIO.A.1
Biology is the study of living things, of life. Any living thing is known as an organism.
Two MAIN themes in biology:
A. MAIN IDEA (theme): Every structure on or in an organism has a function. (or had a function at
one time)
Function (what does it do) = Structure (why it is shaped/built the way it is)
B. MAIN IDEA (theme): All organisms share the same basic characteristics of life. The number of
characteristics may vary from scientist to scientist, sometimes the characteristics are grouped
together, at times they stand alone, but those discussed in the year of your biology class were:
1. Cellular Organization - All organisms are made up of one or more cells AND those cells are
organized in order to perform the necessary functions of life.
2. Metabolism all organisms use energy to carry on life processes.
3. Responsiveness all organisms respond to their environment.
4. Homeostasis all organisms must maintain balance between their internal conditions and the
conditions outside in their environment.
5. Reproduction all organism must reproduce to survive as a species.
6. Heredity during reproduction, organisms pass on their traits to their offspring. The change
over time of these traits in response to their environment is called evolution.
7. Growth all organisms grow, in volume or number of cells, from the time of their birth.
Change in an organism during growth is known as development.
Every topic covered in biology class is related to one of the characteristics of life (listed above)
BIO.A.1 Basic biological principles BIO.A.1.1.1 & BIO.A.1.2.2
1. Describe the characteristics of life shared by all prokaryotic and eukaryotic organisms.
2. Compare cellular structures and their functions in prokaryotic and eukaryotic cells.
Prokaryotes shared by both Eukaryotes
older cells cytoplasm younger cells
less complex DNA more complex
unicellular only ribosomes multicellular or unicellular
no nucleus cell membrane nucleus to protect DNA
no organelles membrane bound organelles
DNA in simple loop DNA in chromosomes
smaller cell less inside larger cell has organelles
3. Describe and interpret relationships between structures and functions at various levels of biological organization.
There are 5 levels of organization.
- Cells that do the same job form tissues, several tissues doing a similar job form an organ, several
organs working together form an organ system, several organ systems form an organism.
Cells ---------- Tissues ---------- Organs --------- Organ Systems ---------- Organism
- Smaller structures have more surface area to volume ratio needed for increased nutrient & gas exchange
- The size and shape of a structure is related to its function.
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Moules

Keystone Exam Review Sheet Biology

Module 1 – Cells and Cell Processes Unit 1a: Introduction to Life BIO.A. Biology is the study of living things, of life. Any living thing is known as an organism.

Two MAIN themes in biology:

A. MAIN IDEA (theme): Every structure on or in an organism has a function. (or had a function at one time) Function (what does it do) = Structure (why it is shaped/built the way it is) B. MAIN IDEA (theme): All organisms share the same basic characteristics of life. The number of characteristics may vary from scientist to scientist, sometimes the characteristics are grouped together, at times they stand alone, but those discussed in the year of your biology class were:

  1. Cellular Organization - All organisms are made up of one or more cells AND those cells are organized in order to perform the necessary functions of life.
  2. Metabolism – all organisms use energy to carry on life processes.
  3. Responsiveness – all organisms respond to their environment.
  4. Homeostasis – all organisms must maintain balance between their internal conditions and the conditions outside in their environment.
  5. Reproduction – all organism must reproduce to survive as a species.
  6. Heredity – during reproduction, organisms pass on their traits to their offspring. The change over time of these traits in response to their environment is called evolution.
  7. Growth – all organisms grow, in volume or number of cells, from the time of their birth. Change in an organism during growth is known as development. Every topic covered in biology class is related to one of the characteristics of life (listed above) BIO.A.1 Basic biological principles BIO.A.1.1.1 & BIO.A.1.2.
  8. Describe the characteristics of life shared by all prokaryotic and eukaryotic organisms.
  9. Compare cellular structures and their functions in prokaryotic and eukaryotic cells. Prokaryotes shared by both Eukaryotes older cells cytoplasm younger cells less complex DNA more complex unicellular only ribosomes multicellular or unicellular no nucleus cell membrane nucleus to protect DNA no organelles membrane bound organelles DNA in simple loop DNA in chromosomes smaller cell – less inside larger cell – has organelles
  10. Describe and interpret relationships between structures and functions at various levels of biological organization. There are 5 levels of organization.
  • Cells that do the same job form tissues, several tissues doing a similar job form an organ, several organs working together form an organ system , several organ systems form an organism****. Cells ---------- Tissues ---------- Organs --------- Organ Systems ---------- Organism
  • Smaller structures have more surface area to volume ratio needed for increased nutrient & gas exchange
  • The size and shape of a structure is related to its function.

Moules Module 1 (continued) – Cells and Cell Processes Unit 1b: The Chemistry of Life - (Characteristic of Life = #1 Cellular Organization – molecular level) Everything (living and non-living) is made up of matter. Matter is made up of atoms. Atoms have three main parts: protons, neutrons, electrons. The number of protons (positive charges) in the nucleus will determine the type of atom. Neutrons are located in the nucleus of an atom but have no charge (+ or - ). Electrons (negative charge) move around the nucleus of the atom and can be lost or gained to form bonds. Element = a substance made up of all the same type of atoms. Compound = a molecule of two or more different atoms held together by a bond. Molecule = the smallest bit of a compound. Three types of bonds were discussed:

  1. Covalent bond = strongest of the bonds, occurs when electrons are shared between atoms.
  2. Ionic bond = the force of attraction when atoms lose electrons (become a positively charged ion) or gain electrons (become a negatively charged ion).
  3. Hydrogen bonds = weakest of the bonds, occurs when a positive portion of a polar compound is attracted to a negative potion of a polar compound. LIVING things are made up of four basic compounds: Carbohydrates, Lipids, Proteins, Nucleic Acids These four types of compounds are known as biological macromolecules and are made up of repeating units. Molecules made up of repeating units are known as Polymers, each individual unit is called a monomer. The Chemical Basis for Life BIO.A.2.2.
  4. Organic compounds (made with carbon from living things) and inorganic compounds (no carbon, not living)
  5. Organic compounds – MACROMOLECULES – polymers made up of monomers A. Carbohydrates - elements carbon, hydrogen and oxygen. Hydrogen to oxygen ratio of 2:1. Function = main source of energy in the body. Monosaccharides (glucose, fructose or galactose) are the monomers of carbohydrate polymer. Chemical structure is a carbon ring: many rings make a polysaccharide. B. Lipids – elements of Carbon, hydrogen and oxygen. Lots of Carbon and hydrogen atoms, very little oxygen atoms. Hydrocarbon tail and carboxyl head. The fatty acid is the monomer of a lipid polymer. Function = control the movement of water and nutrients in the cells. They do not dissolve in water. Main structural unit in cell membranes. Triglycerides – large molecules of lipids Oils – triglycerides that are liquids atroom temperature. Found in plants Fats – triglycerides that are solid at room temperature. Found in animals Wax – waterproof, found in plants and animals Steroid – made up of 4 carbon rings. Found in hormones, venoms, and plant poisons

Moules pH scale runs from 1 (very acidic) to 14 (very basic/alkaline). A pH of 7 is neutral – many living things live in a range around pH 7. Module 1 (continued) – Cells and Cell Processes Unit 2: Cell Structure and Function BIO.A. Organelle Notes Structure Function Location Cell like a City co mm on to bot h Pro kar yot es and Eu kar yot es Plasma Membrane a/k/a Cell Membrane Semi-Permeable Phospholipid Bilayer (2 layers) contains embedded proteins Barrier (fence) Controls what comes in or out of the cell Outer boundary Barrier around the city (fence) Cytoplasm 2/3 of cell weight Watery-gel 1. holds organelles

  1. provides shape
  2. provides location for biochemical reactions inside plasma membrane Everything inside the City limits Ribosome small (tiny) spherical^ numberous rRNA strands site of protein synthesis (building)
  3. free floating in cytoplasm
  4. attached to ER Protein factories DNA Hereditary material on chromosomes^ -^ found nucleotides linked together contains the code for building proteins nucleus City Blueprints Fo un d on ly in eu ka ry oti c ce lls

bo th pl an ts & an im al s Cytoskeleton

  1. Microfilaments
  2. Microtubules
  3. intermediate fibers network of protein fibers provide shape and support organelles cytoplasm (^) Infrastructure (bridges, sidewalks, power poles) Nucleus (Nucleolus) enclosed in a double membrane double membrane contains nuclear pores for movement in or out Nucleus - protects the DNA Nucleolus - builds ribosome parts cytoplasm City Hall (control center) Endoplasmic Reticulum 2 types:
  4. Rough ER (ribosomes attached)
  5. Smooth ER (no ribosomes) Series of membranes provide rapid movement through the cytoplasm all through the cytoplasm (^) HighwaysStreets & Golgi Apparatus large, usually only one a cell Stack of membranes and vesicles (membrane sacs) repackages proteins for shipment in and out of the cell cytoplasm Post Office Lysosome a type of vesicle vesicle (hollow membrane sac) breakdown of old parts, food, foreign material cytoplasm Recycle Center Vesicles & Vacuole Large central Vacuole in plants Vesicles are smaller then vacuoles (vesicles are typically spherical) hollow containers made from membranes
  6. Store materials
  7. transport materials
  8. provide chambers for chemical reactions cytoplasm Warehouse (storage) Mitochondria
  9. Contain their own DNA
  10. Form the basis of endosymbiotic theory Double membrane: inner membrane is folded into Cristae (provide more surface area for reactions) provides the energy (ATP) needed for cell processes cytoplasm Power Plant

Moules pl an t ce lls on ly Plastids

  1. Chloroplast
  2. Chromoplast
  3. Leucoplast Membrane bound organelles - internal structures vary capture light energy and convert it into chemical energy cytoplasm (^) Food Processing factories Cell Wall conatins tiny holes for water and nutrient movement rigid layer of lignin fibers and pectin glue: Complex Carbohydrates (cellulose) Provides support and protects cell. Allows plants to remain upright. outside plasma membrane Wall around the city (protection) BIO.A.4 Homeostasis and Transport
  4. Identify and describe the cell structures involved in transport of materials into, out of, and throughout a cell.
  • Cell membrane (plasma membrane) is composed (made up) of two layers of phospholipids. A phospholipid is formed from a water loving (hydrophilic) head and a two water fearing (hydrophobic) tails.
  • Imbedded in the lipid bilayer are proteins: transport proteins, enzymes, cell surface markers and receptor proteins.
  • Transport through a cell membrane (plasma membrane) o Passive transport – no energy (ATP) needed – simple diffusion, facilitated diffusion (ion channels, gated channels, transport proteins) o Active transport – energy is needed (ATP) because substances are being moved against their concentration gradients (from low to high) – sodium-potassium pump (protein carrier) o Active transport – endocytosis (building a vesicle) to bring large particles into the cell and exocytosis – building a vesicle to move large particles out of the cell (golgi apparatus does this)
  1. Explain mechanism that permit organisms to maintain biological balance between their internal and external environments.
  • Diffusion – is the movement of a substance from an area of high concentration to an area of low concentration (down a concentration gradient) until equilibrium is reached.
  • Osmosis – the movement of water through a plasma membrane (cell membrane) from an area of high free water concentration to an area of lower free water concentration. BIO.A.3 Bioenergetics
  1. Identify and describe the cell structures involved in processing energy.
  2. Identify and describe how organisms obtain and transform energy for their life processes.
  • Photosynthesis captures the light energy and uses it to convert carbon dioxide and water into a carbohydrate (monosaccharide) and oxygen sunlight
  • 6CO 2 + 6H 2 O → C 6 H 12 O 6 + 6O 2
  • Photosynthesis takes place in the chloroplast (a plastid structure found only in plant cells)
  • Chloroplasts are made up of thylakoid membranes (where the light reactions take place) and the stroma (where the dark reactions also known as Calvin Cycle also known as carbon fixation takes place)
  • A photon of light excites the pigments molecules (chlorophyll is the main one – green) which passes it to photosystem II and photosystem I – electron transport chains. This is the light reaction.
  • Carbon dioxide cycles through the Calvin Cycle (dark reactions) and produces organic molecules (sugar)

Moules

  • P1 (result from self- pollination) – F1 are the offspring of a cross pollination of two P1’s – F2 is a result of self-pollination of the F1 generation. F1 results (all dominate phenotypes): F2 results 3:1 ratio of dominant to recessive traits.
  • Non-Mendelian patterns of inheritance – sex-linked traits (on the X or Y chromosome), co-dominance (both alleles are expressed at the same time – blood type AB), incomplete dominance (dominant alleles are blended together – red x white = pink), multiple alleles (results in 4 different phenotypes – blood type A, B, AB or O)
  1. Describe how the process of DNA replication results in transmission and/or conservation of genetic information (Chapter 13) o DNA is composed of nucleotides (5 carbon sugar deoxyribose, phosphate group and nitrogen base) Nitrogen bases are purines (Adenine and Guanine) or pyrimidines (Thymine and Cytosine) o DNA replication occurs during the S phase in Interphase. Helicase (enzyme) unzips the DNA double helix and then DNA polymerase (enzyme) matches up the open base pairs A-T (adenine to thymine) G-C (guanine to cytosine)
    1. Explain how genetic engineering has impacted the fields of medicine, forensics, and agriculture. (chapter

o Genetically engineering food (agriculture) – seedless grapes, seedless watermelon, hybrid corn, antibiotic meats. o Forensics – biometrics (your personal DNA for identification); Medicine – gene therapy

  1. Explain the process of protein synthesis (transcription, translation, and protein modification) – (chapter 13)
  • Transcription is in the nucleus – RNA polymerase binds to a promoter region of DNA and unzips it. RNA polymerase matches nucleotides to one DNA open strand and builds mRNA (transcribes the message)
  • mRNA moves from nucleus (through nuclear pore) into the cytoplasm to the ribosome (rRNA) where it is held in place.
  • tRNA translates the mRNA codons (3 base sequence code) and brings amino acids which form peptide bonds. Begins coding with a start code (Methionine) and ends with a stop code.
  1. Describe how genetic mutations alter the DNA sequence and may or may not affect phenotype (silent, nonsense, frame shift) – (Chapter 13)
  • Mutations occur during replication, transcription or translation. They may OR may not affect the protein to be built. Silent mutation (no change); Nonsense (protein built does not work at all); Frameshift (all amino acids after the mutation are incorrect for the protein): Point mutation – may change one Amino Acid or change nothing. Insertion or deletion – will add or delete an Amino Acid if in multiple of 3. BIO.B.3 Theory of Evolution
  1. Explain how natural selection can impact allele frequencies of a population.
  • Natural Selection is a theory where a process in nature in which organisms possess inherited traits are better able to survive and reproduce compared to others of their species. (Charles Darwin pioneered) o 1. Variation - individuals among a species are different (have different forms of traits) o 2. Overpopulation – a species makes more offspring than can survive in nature) o 3. Selection – the environment will select those traits that are better suited for survival o 4. Adaptation – over time the favorable traits will increase in the species population
  • Charles Darwin published his theory of Evolution my means of Natural Selection in 1859. He was influenced by Lamarck, Malthus, Lyell, Hutton and Cuvier.
  • Darwin sailed in the ship: HMS Beagle and studied finch beaks and tortoises in the Galapagos Islands
  1. Describe the factors that can contribute to the development of new species.
  • Speciation = formation of a new species as a result of evolution o Microevolution - study how genes change in populations (mate choice, mutation, migration, genetic drift, natural selection o Macroevolution – study of patterns of diversity or speed of change in a species (extinction, gradualism, punctuated equilibrium, convergent evolution, coevolution, adaptive radiation.
  1. Explain how genetic mutations may result in genotypic and phenotypic variations within a population.
  • Mutations can lead to altered proteins which may or may not be favorable for survival.
  • Most mutations are NOT good. Rarely they allow an individual to better survive and reproduce, thereby increasing the number of individuals in the population with that mutated trait. Over time the population changes to include that trait that was originally mutated.

Moules

  1. Interpret evidence supporting the theory of evolution - fossils, biochemical, homologous structures, embryological
    • Fossil records of older species (giant armadillo) giving rise to current species (armadillo)
    • Biochemistry - comparison of DNA or proteins among related species
    • Anatomy – comparison of homologous structures (human arm, bat wing, alligator leg)
    • Embryology – embryos of human, rabbit, frog, fish all look the same early in development become different during development (suspected common ancestor)
  2. Distinguish between the scientific terms: hypothesis, inference, law, theory, principle, fact, and observation.
    • Scientific Method (basic) – Observe, question, predict (hypothesis), investigate (experiment), evaluate (analyze data looking for patterns), communicate (good and bad results) o Hypothesis – an IF – THEN statement (not a question) that is testable. Based on observations o Theory – system of ideas that explains may related observations and supported by evidence from scientific investigations o Investigation (experiment) – test one factor (variable) at a time. A controlled experiment must have all factors the same and test the: ▪ Independent variable – the variable to be tested ▪ Dependent variable – the variable to be measured to see if the independent variable has an effect on the investigation. o Observations – quantitative (has a number in it) OR qualitative (no numbers) ▪ 37 frogs were in the pond (quantitative) ▪ The frogs were green and brown (qualitative) BIO.B.4 Ecology Describe the levels of ecological organization (organism, population, community, ecosystem, biome, biosphere.) An organism is a single living thing.
  • Many of the same organisms living and breeding together form a population o Many populations of different organisms living and interacting together is a community. An ecosystem is the living and non-living parts of the environment (Biotic and Abiotic)
  • Biome is a large geographical area that shares similar weather (sunlight and precipitation) they will have distinct organisms (plants and animals) adapted to that environment. ▪ Biosphere is the zone on the earth were life exists (total of all ecosystems)
  1. Describe characteristics biotic and abiotic components in aquatic and terrestrial ecosystems.
    • Biotic – the living things in an ecosystem. (plants, animals, bacteria, fungi - community)
    • Abiotic – the non-living things in an ecosystem. (water, weather, rocks, sunlight, shade, etc..)
  2. Describe how energy flows through an ecosystem (food web, food chain, energy pyramids) Food Web Food Chain Energy pyramid

Moules PDE Keystone 2015 Sampler Module 1 Multiple choice: Which characteristic is shared by all prokaryotic and eukaryotic organisms? A. The ability to reproduce asexually B. The ability to make their own food C. The need for a source of energy D. The need for oxygen for respiration

  1. Life function are performed at many levels of biological organization. Which level of biological organization is the simplest level at which a structure can support life functions? A. Cell B. Tissue C. Organelle D. Organ system
  2. The opening of the stomata allows water to evaporate from inside the leaf in a process known as transpiration. As this occurs, water molecules cling to one another and pull water in a continuous stream up the stem of the plant from the roots to the leaves. Which property of water makes the movement possible? A. Cohesion B. Freezing point C. High specific heat D. Temperature-dependent density

Moules

  1. Cells are largely made of organic compounds that contain carbon. Which property of the carbon atom makes it an essential component of organic compounds? A. Carbon is a nonmetal B. Carbon oxidizes to carbon dioxide C. Carbon is solid at room temperature D. Carbon can form four covalent bonds
  2. Plant cells use sunlight to make their own food. Which structure allows plant cells to perform this function? A. Nucleus B. Vacuole C. Chloroplast D. Mitochondrion
  3. Which statement best explains why cellular respiration in plants and other organism is dependent on photosynthesis? A. Photosynthesis is one of the final steps in cellular respiration. B. Photosynthesis provides the materials that fuel cellular respiration C. Photosynthesis absorbs excess energy produced by cellular respiration D. Photosynthesis absorbs materials that are catalyzed during cellular respiration Molecules needed for Protein SynthesismRNAtRNAamino acidsATP molecules
  4. A plant cell uses the molecules in the list above to synthesize a protein. What role do the ATP molecules play in the protein synthesis process? A. They provide energy. B. They increase activation energy. C. They convert energy into hereditary information. D. They absorb excess energy to prevent overheating.

Use the diagram below to answer question 8.

Membrane Protein Outside of cell Surface Inside of cell

Moules Antibiotic Action on a Bacterium antibiotic rupture before after

  1. The function of which human organ is most like the cell walls of bacteria? a. heart b. liver c. pancreas d. skin 12.Which statement best describes how antibiotics affect cellular homeostasis? A. Antibiotics remove chloroplasts from plant cells to cause starvation. B. Antibiotics interfere with the transport of intracellular and extracellular materials. C. Antibiotics increase the rate of DNA replication in human cells by forming nucleotides. D. Antibiotics decrease the rate of cellular respiration in animal cells by producing oxygen.

Moules Part A: Describe two similarities in the structure of the organic molecules shown. Similarity 1: Similarity 2: Part B: “Structure determines function” is an important concept to biology. Select one of the organic molecules shown and explain how its structure is related to its function.

Moules

3. Which effect is most likely caused by nondisjunction during meiosis? A. an increase in nuclei B. an extra chromosome C. only two types of nitrogenous bases D. increased survival benefits from traits 4. A genetic mutation involving a single base causes an error that affects the sequence of the next 500 amino acids in a protein. Which type of mutation could have produced this type of error in the protein? A. silent B. nonsense C. frame-shift D. substitution 5. New technologies enable oils to be extracted from plants to make renewable biodiesel fuel. Scientists have altered the genome of a specific plant species to increase the amount of oil produced by each plant. Which statement explains why this technology most likely benefits farmers? A. It makes each plant more resistant to disease. B. It lowers the cost of each acre of plants cultivated. C. It increases the value of each acre of land cultivated. D. It eliminates the processing needed to extract plant oils. 6. A population of squirrels was separated during the formation of the Grand Canyon. Over time the squirrels, separated by the canyon walls and the Colorado River, became unique species. Which mechanism most likely caused the development of the new species? A. habitat preference B. increased gene flow C. geographic isolation D. behavioral isolation 7. A researcher observes two species of frogs in the same area. Both species have a similar diet. One species breeds in fast-moving streams, while the other species breeds in ponds. Both species are similar in appearance and have very similar DNA. Which information provides the best evidence that these two species descended from a common ancestor? A. the species’ similar diets B. the species’ shared habitat C. the species’ mating behaviors D. the species’ physical characteristics

Moules

8. Which description is the best example of a population? A. all of the red foxes in a forest B. all of the red foxes in every forest C. all of the organisms in a forest D. all of the organisms in every forest 9. Which energy transfer most likely occurs between organisms in the food web? A. from owl to fox B. from rabbit to fox C. from sparrow to grass D. from mouse to grasshopper 10. In Pennsylvania, a nonnative plant called stiltgrass out-competes native plants in many forest ecosystems. Which statement best describes how the spread of stiltgrass negatively affects native herbivores? A. Stiltgrass stops the life cycles of native herbivores. B. Stiltgrass reduces the size of the native plant populations. C. Stiltgrass increases the flow of energy through the ecosystem. D. Stiltgrass attracts other nonnative plants to the forest ecosystem. Four Locations of Aye-ayes

Moules Part B: Describe one possible effect that a nonnative species can have on a native ecosystem and explain why this effect might occur. Use the diagram below to answer question 14. Pea Flower Color Cross

14. In pea plants, the flowers can be purple or white. The diagram shows three generations of pea plant crosses.

Moules Part A: Using the pea flower color cross, identify the pattern of inheritance shown and explain how the cross shows this pattern. Part B: Explain how farmers could ensure that they only grow white flowers.