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MMUu Levy
Mwanawasa
Medical
On
University
DEPARTMENT OFBIOCHEMISTRY
MCT 201 GENERAL BIOCHEMISTRY^ TEST^ ONE^2022
MBCHB YEAR 2
Examiner: Shandele Ginnethon
Instructions:
There are 35 questions in this TEST, answer ALL in the GRID provided.
Present Your^ Work Neatly.
Total Marks =
DURATION: 45 minutes
- A (^) patient "X" is (^) struggling with (^) consistent (^) high blood gucose levels.^ Dr.^ Handson suspects lack^ of^ Insulin^ production in the (^) patient. However, (^) laboratory results (^) show that (^) patient "X" (^) has (^) sufficient Insulin (^) secretion. What do you think^ could be wrong with patient "X*"?
(a) (^) Regular intake of (^) glucose
(6) Eating fats
(c) Insulin resistance
(d) Starvation
- (^) The Bohr (^) Effect is (^) a physiological (^) phenomenon in (^) which (^) hemoglobin's (^) oxygen binding affinity is..
(a) (^) Inversely related (^) both to (^) acidity and to the (^) concentration of (^) carbon
(b) dioxide.
Directly related^ both to (^) acidity and to (^) the (^) concentration of (^) carbon (^) dioxide. C) (^) Inversely related (^) both to (^) oxygen and (^) to the (^) concentration of
(d) carbon^ dioxide
Directly related both (^) to (^) oxygen and to the (^) concentration of (^) carbon dioxide
3. Substances on which enzymes act to convert them into
(^) products are (^) called...?
(a) Co-factors
(b) Substrates
(c) Co-Enzymes
(d) Apo-Enzymes
- (^) Enzymes have (^) immense (^) catalytic (^) powers and (^) accelerate reactions at (^) least a (^) million
times by..
(a) Increasing the energy of activation.
(b) Reducing the energy of activation
(c) Increasing the substrate concentration
(d) Reducing the collision frequency
- (^) Enzymes that contain (^) tightly bound metal (^) ions are (^) known as... (a) Metalloids b) Metallo-enzymes
(c) Multi-enzymes
(d) Apoenzyme
- The (^) enzyme alcohol (^) dehydrogenase is (^) an (^) example of.?
(a) Transferase
(6) Hydrolase
(c) Oxido-reductase
(d) Isomerase
- A substance "X" moves from higher concentration to lower concentration across the cell membrane. This movement initiates movement of another substance "Y" from lower concentration to higher concentration against a concentration gradient. This
type of transport is called..
(a) Vesicular transport
(b) Primary active transport
(c) Secondary active transport
(d) Facilitated diffusion
13. Dr. Chishimba has been seeing a patient for a period of three months. During his
latest check, he noticed that the patient had continued losing weight. His muscle size reduced drastically. Which of the following organelles could be impaired in this
patient?
(a) Cytosol
(b) Ribosomes
(c) Mitochondria
(d) Golgi bodies
- Rumbidzai has problems utilizing the glucose in her body cells. After carrying out a number of tests on her, it is almost evident that the glycolytic pathway could be shut down. Which of the following cell regions could be faulty?
(a) Cytosol
(b) Lysozymes
(c) Mitochondria
(d) Ribosomes
- Which of the following is a not an example of endocytosis?
(a) Pinocytosis
(b) Phagocytosis
(c) Receptor mediated^ endocytosis
(d) Exocytosis
- A village boy nearly drowned in a river just next to their family house. After close
examination of the water environment in which the boy almost drowned, it was discovered that the water was very salty. As a reliable biochemist, what is the first
line of treatment you can give to prevent the boy's cells from dying?
(a) Give him Oral rehydration salts
(6) Give him a concentrated sugar solution
(c) Give him pure water
(d) Give him a salt solution
T7. In a water molecule, each oxygen atom is partially negative and each hydrogen atom
is partially positive. This phenomenon is called..
(a) Partial positivity
(b) Electronegativity (c) Charge separation (d) Dipole moment
- An electrostatic attraction between the oxygen atom of one water molecule and the hydrogen of another is called..
(a) Dipole-dipole interaction
(b) Intermolecular force (c) Hydrogen bond (d) Hydrophobic interaction
19. The forces that hold the non-polar regions of the molecules together are called..
(a) Hydrophobic interactions
(6) Hydrogen bonds
(c) lonic bonds
(d) Intermolecular bonds
- (^) Electrostatic interactions between (^) oppositely (^) charged
groups within^ or^ between
biomolecules are termed....
(a) lonic bonds
b) Covalent bonds
(c) Salt bridges
(d) Di-sulphide bonds
- (^) Imagine (^) you walked (^) into (^) a (^) food (^) store to (^) some (^) fat Which (^) of (^) the containing^ foods^ for^ your (^) house following items (^) would (^) you leave (^) out on
your list^ of^ fats?
(a) Oils b) Waxes (c) Dextrose (d) Steroids
- A biomedical scientist wants to extract some fats from a mixture of samples. Using as
much biochemical principles as possible, which of the following solvents do you
think would be ideal for him to use in the extraction
process?
(a) Polar solvents
(6) Non polar solvents
(c) Pure water
(d) Sucrose solution
- Precursor and derived lipids are obtained from..?
(a) Hydration of simple and compound lipids b) Condensation of simple and compound lipids
(c) Hydrolysis of simple and compound lipids
(d) Ionization^ of^ simple^ and^ compound^ lipids.
30. What^ do^ you think^ is^ the^ correct^ justification^ of^ unsaturated^ fats^ being^ liquid^ at^ room
temperature?
(a) Because^ they^ have^ weak^
bonds
(b) Their^ particles^ are^
close (^) together (c) Because^ of^ the^ trans-double^ bond that^ forms^ a^ kink in the structure
(d) Because^ of^ the^ cis-double^
bond that^ forms^ a^ kink^ in^ the^ structure.
31. Mervis^ is^ nurse^ at^ Levy^
Mwanawasa University Teaching Hopsital. She is currently
taking care^ of^ a^ patient^ recovering^ from severe atherosclerosis. Which^ of^ the
following lipoproteins^ should^ Mervis^ patient^
eat more to improve her current
condition?
(a) VLDL b) IDL (c) LDL (d) HDL
32. Fatty acids are very critical molecules in our bodies. The basic structure of a fatty
acid has a (^) carboxylic acid on one end and (^) a..
(a) Carbonyl group on the other end
b) Methyl group on the other end (c)Hydrogen groups on the end (d) The alpha group on the other end
- Dr. wezi is cramming for a biochemistry to be witen in the next 30 minutes. He has so many slides to read through. Unfortunately he feels very tired and hungry. Which of the following foods would be ideal for his energy needs as he prepares for the test?
(a) Sausage and chips (b) Proteins () Dextrose (d) Lipids
- Which of the following stimulate contractions of the uterine smooth muscles during menstruation and labour?
(a) Leukotrienes b) Thromboxane (c) Prostaglandins (d) Steroids
- A patient "X" has been struggling with type 2 diabetes mellitus for 10 years. Asa voung scientist you are working so hard to try and reverse this condition in patient X. Using as much biochemical principles as possible, which of the following steps
would initiate^ in^ trying to^ reverse^ type^2 diabetes?
(a) Give^ the^ patient^ Insulin^ doses^ regularly
(b) Tell^ them^ to^ stop^ eating^ carbohydrates
(c) Focus^ on^ reversing^ insulin^ resistance^ of^ their^ cells
(d) Tell^ them^ to^ stop^ eating^ fats
THE END!
