Myasthenia Gravis Lecture notes, Lecture notes of Nursing

Myasthenia Gravis Lecture notes for final unit & final exam

Typology: Lecture notes

2025/2026

Uploaded on 12/04/2025

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Specific Care for the Patient with Myasthenia Gravis
Contributing Factors
Only voluntary muscles
Developmental:
o Occurs mor in women
o Onset between 20-40 years of age
Physiological:
o Autoimmune disorder
o Thymus gland site of antibody production
Can get a thymectomy
Clinical Manifestations
Ocular
o Diplopia double vision
o Ptosis Droopy eye
Facial
o Weakness
o Dysphagia
o Dysarthria
Musculoskeletal
o Fatigue
o Generalized weakness
Respiratory
o Weak intercostal muscles cause decreased vital capacity
o Dyspnea
o Respiratory failure
Nutrition
o Aspiration
o Inability to chew/swallow/move tongue
o Malnutrition
o Dehydration
Myasthenic Crisis
o Severe exacerbation of adaptations
Diagnostic Tests
Acetylcholinesterase inhibitor test
o Tensilon Test will determine if the patient has MS
o Do not give during crisis
Acetylcholine receptor antibody serum level
MRI Thymus gland
EMG can test muscles for deterioration
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Specific Care for the Patient with Myasthenia Gravis

Contributing Factors

  • Only voluntary muscles
  • Developmental: o Occurs mor in women o Onset between 20-40 years of age
  • Physiological: o Autoimmune disorder o Thymus gland site of antibody production ▪ Can get a thymectomy Clinical Manifestations
  • Ocular o Diplopia – double vision o Ptosis – Droopy eye
  • Facial o Weakness o Dysphagia o Dysarthria
  • Musculoskeletal o Fatigue o Generalized weakness
  • Respiratory o Weak intercostal muscles cause decreased vital capacity o Dyspnea o Respiratory failure
  • Nutrition o Aspiration o Inability to chew/swallow/move tongue o Malnutrition o Dehydration
  • Myasthenic “Crisis” o Severe exacerbation of adaptations Diagnostic Tests
  • Acetylcholinesterase inhibitor test o Tensilon Testwill determine if the patient has MS o Do not give during crisis
  • Acetylcholine receptor antibody serum level
  • MRI – Thymus gland
  • EMG – can test muscles for deterioration

Nursing Diagnosis

  • Risk for aspiration
  • Ineffective breathing pattern
  • Deficient knowledge
  • Fatigue
  • Impaired verbal communication
  • Fear/anxiety
  • Impaired physical mobility
  • Risk for infection
  • Disturbed sensory perception
  • Self-care deficit syndrome
  • Imbalanced nutrition Nursing Interventions
  • Support respiratory function
  • Maximize mobility
  • Conserve energy → cluster care
  • Assess response to plasmapheresis
  • Provide nutritional support
  • Provide care r/t thymectomy
  • Refer to home care services
  • Administer medications: o AnticholinesterasePyridostigmine (Mestinon) o Immunosuppressants ▪ Prednisone o Cytotoxic ▪ Azathioprine ▪ Cyclophosphamide
  • Educate patient/family o Medication management o Energy conservation o Stress reduction o Strategies for ocular adaptations o Prevention and management of complications