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The causes, symptoms, and treatment of hyperthyroidism. It explains that hyperthyroidism is the excessive concentration of thyroid hormones in the tissues caused by increased production of thyroid hormones, excessive release of thyroid hormones, of an endogenous or exogenous extra-thyroidal source. The document also discusses the risk factors and correlation to the etiology of hyperthyroidism. It explains the diagnosis and medical management and treatment of hyperthyroidism by the APN/FNP. The document concludes by emphasizing the importance of early detection and diagnosing in medical management and treatment of the disorder of Hyperthyroidism.
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C H A M B E R L A I N C O L L E G E O F N U R S I N G N R 5 0 7 : L E A D E R S H I P A N D R O L E O F T H E A P N M A R C H 1 6 , 2 0 1 9
Adrenergic – most frequent S/S Palpitations, tachycardia, anxiety, tremors, jitteriness, diaphoresis, intolerance for heat, frequent stare, Cardiovascular , rapid and or irregular pulse (in atrial fibrillation), dyspnea, orthopnea and peripheral edema seen in heart failure. Cutaneous - Onycholysis (Plummer nails), patchy or generalized hyperpigmentation usually of the face and neck.. Initial Presenting Signs and Symptoms Part 1
Initial Presenting Signs and Symptoms Part 2 Hypermetabolism –common weight loss in spite of increased appetite, fever if the patient is in thyroid storm. Neuromuscular Sharp peripheral reflexes with accelerated relaxation phase and weakness of proximal muscles Neuropsychiatric Anxiety, rapid, pressured speech, insomnia, psychosis with severe cases. Ocular Increased lacrimation, incomplete closure of the eyes when sleeping, photophobia, increased eye sensitivity when exosed to wind or smoke, feeling of grit or foreign body in the eyes
ETIOLOGY OF HYPERTHYRODISM
cause of hyperthyroidism in the United States Process- The disease presents an autoimmune process in which antibodies stimulate the TSH receptor thus leading to an overproduction of thyroid hormones Risk factors Female have higher incidence and personal or family history of an autoimmune disorder
ETIOLOGY OF HYPERTHYRODISM Toxic adenoma (Plummer disease) Process- Somatic mutation in TSH receptor or Gs alpha gene in a thyroid nodule Risk Factors - nodules arise from the frequent replication of clonogenic cells that leads to a somatic activating mutation of TSH receptors..
Drug-induced thyroiditis Process- Overproduction of thyroid hormones (amiodarone-induced thyrotoxicosis type 1) or release of preformed thyroid hormones (amiodarone-induced thyrotoxicosis type 2, interferon alfa, interleukin-2, or lithium)
(^) Hyperemesis gravidarum High level of β- hCG stimulates TSH receptors Process- Hyperemesis gravidarum High level of β-hCG stimulates TSH receptors (^) Subacute granulomatous (de Quervain) thyroiditis Process- Painful inflammation of the thyroid gland caused by viral infection,
Diagnosing of Hyperthyroidism Radioiodine uptake test Thyroid scan (^) Thyroid Ultrasound
Pharmacological Treatment of Hyperthyroidism Anti-thyroid medications (^) Beta-Blockers
(^) Assessment and Evaluation of patient Plan of treatment; Teaching & Education Coordination of care if appropriate Summary of the care and implications for the Advanced Practice Nurse