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This document provides a complete set of questions and 100% accurate answers on central nervous system sensory and motor disorders for the NR507 Advanced Pathophysiology course at Chamberlain University. It covers neurological conditions such as Parkinson’s disease, multiple sclerosis, stroke, neuropathies, and spinal cord injuries, along with relevant neuroanatomy and pathophysiological mechanisms. Ideal for exam prep, Edapt modules, and clinical case reviews.
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There are some very well - known causes of Alzheimer's disease - Accurate answers False The effect of dementia on the brain results in cerebral cortex swelling - Accurate answers False Which of the following is true regarding dementia - Accurate answers More than one type of dementia can co - exist in a patient In Alzheimer's disease , the microtubules become misfolded and tangled which alters their function - Accurate answers True _________ involves an implantable device that directly sends electrical signals to the basal ganglia which counteracts the aberrant signaling in Parkinson's disease - Accurate answers Deep brain stimulation This is involuntary shakiness most noted in the hands in a pill - rolling fashion - Accurate answers Tremor This is a series of catches or stalls in movement as the extremity is passively moved by someone else. - Accurate answers Rigidity Results from difficulty initiating movement - Accurate answers Bradykinesia Postural instability is a late feature of PD - Accurate answers True Parkinson's disease ( PD ) is a movement disorder where the dopamine - producing neurons and substantia nigra of the brain undergo neuron _________ - Accurate answers degeneration Which of the following is considered the main treatment strategy for Parkinson's disease to increase dopamine signaling in the brain? - Accurate answers Administer levodopa Difficulty or unclear speech that is due to plaques in the brain stem - Accurate answers Dysarthria This is involuntary rapid eye movement due to plaques on the nerves that cause eye movements - Accurate answers Nystagmus This can be caused by plaques along the motor pathways of the spinal cord which can affect outbound signals and skeletal muscle control - Accurate answers Intention tremor Lhermitte's sign is an electric shock that runs down the back and radiates in the limbs when bending the neck forward - Accurate answers True Multiple sclerosis is classified as - Accurate answers a type IV hypersensitivity reaction
Remyelination takes place for a period of time. There is no disability between episodes - Accurate answers Relapsing Remitting MS ( RRMS ) The immune attack becomes constant over time which causes a steady progression of disability - Accurate answers Secondary Progressive MS ( SPMS ) There is one constant attack on the myelin - Accurate answers Primary progressive MS ( PPMS ) This also involves one constant attack where the disability happens very fast - Accurate answers Progressive Relapsing MS ( PRMS ) diagnostic tests used to diagnose Multiple Sclerosis - Accurate answers An MRI that shows multiple CNS lesions called white matter plaque Cerebrospinal fluid analysis Visual evoked potential Multiple sclerosis is a Type III hypersensitivity reaction - Accurate answers False Physical therapy and cognitive rehabilitation therapy can be helpful with sensory , motor and cognitive symptoms of Multiple Sclerosis - Accurate answers True Which of the following is part of Charcot's Triad?. - Accurate answers Nystagmus Primary progressive MS ( PPMS ) involves one constant attack on the myelin which causes a steady progression of disability over the person's lifetime - Accurate answers True Select all drugs that are used in the treatment of Multiple Sclerosis - Accurate answers Intravenous immunoglobulin ( Flebogamma ) Methylprednisolone ( Solumedrol ) Cyclophosphamide ( Cytoxan ) Which of the following is considered a non - pharmacological management strategy for restless leg syndrome? - Accurate answers Exercise Discontinuation of an SSRI if one is being taken Avoid caffeine , alcohol or nicotine Drugs used to treat restless leg syndrome include : - Accurate answers Dopamine drugs Benzodiazepines Opioids Anticonvulsants Alpha - 2 agonists Iron Select all items below that are part of the DSM - 5 criteria for diagnosing restless leg syndrome : - Accurate answers Experiences urge to move the legs usually followed by discomfort if movement not performed. Is worse at night and associated with inactivity. Symptoms improve with movement. Cannot be due to another cause such as intoxication or medication. Restless leg syndrome is thought to be due to impaired iron regulation and homeostasis in the body - Accurate answers True