NUR 635 - Midterm Exam DR.TYLER, Exams of Nursing

NUR 635 - Midterm Exam DR.TYLER

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NUR 635 - Midterm Exam
DR.TYLER
1 / 14
1.
Often prescribed with levodopa/carbidopa in the
treatment of Parkinson's Disease
2.
What medication may cause serious or possibly
life-threatening sleep behaviors, such as sleep dri-
ving?
3.
Taking too much of this type of drug can make you
"blind as a bat" or "mad as a hatter"
Bromocriptine
Ambien
Anticholinergics, antimus-
carinics
4.
Absorption, Distribution, Metabolism, excretion
Pharmacokinetics
5.
Drugs used to relieve a myasthenic crisis
Neostigmine,
pyridostigmine
6.
This drug has a very narrow therapeutic index and
high risk for toxicity, therefore levels should be
monitored frequently
7.
The drug class that carries an increased risk of sui-
cidality in children, adolescents, and young adults
Lithium
SSRIs/SNRIs
8.
The antidote for organophosphate poisoning
Atropine
9.
This drug class double the rate of mortality in older
Antipsychotics
adults with dementia
10.
In infants, this is not fully developed and therefore
infants are more sensitive to CNS drugs
11.
Time of development that fetus is at highest risk of
teratogenicity from a drug
12.
Do not stop this class of drug abruptly due to an
increased risk of cardiovascular events
Blood
Brain
Barrier
First
trimester
Beta-
blockers
pf3
pf4
pf5
pf8
pf9
pfa
pfd
pfe

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  1. Often prescribed with levodopa/carbidopa in the treatment of Parkinson's Disease
  2. What medication may cause serious or possibly life-threatening sleep behaviors, such as sleep dri- ving?
  3. Taking too much of this type of drug can make you "blind as a bat" or "mad as a hatter" Bromocriptine Ambien Anticholinergics, antimus- carinics
  4. Absorption, Distribution, Metabolism, excretion Pharmacokinetics
  5. Drugs used to relieve a myasthenic crisis Neostigmine, pyridostigmine
  6. This drug has a very narrow therapeutic index and high risk for toxicity, therefore levels should be monitored frequently
  7. The drug class that carries an increased risk of sui- cidality in children, adolescents, and young adults Lithium SSRIs/SNRIs
  8. The antidote for organophosphate poisoning Atropine
  9. This drug class double the rate of mortality in older Antipsychotics adults with dementia
  10. In infants, this is not fully developed and therefore infants are more sensitive to CNS drugs
  11. Time of development that fetus is at highest risk of teratogenicity from a drug
  12. Do not stop this class of drug abruptly due to an increased risk of cardiovascular events Blood Brain Barrier First trimester Beta-blockers
  1. Agents that indirectly block the breakdown of acetylcholine and are often used in treatment of Alzheimer's Disease
  2. Adverse drug reaction that causes difficulty speak- ing and chewing and worm-like movements of the tongue Cholinesterase inhibitors Tardive Dyskinesia
  3. Receptor found in the lungs that causes bronchodi- Beta 2 Receptors lation when activated
  4. This drug has led to the death of children in ultrara- Codeine pid metabolizers as 10% of the drug is converted to morphine
  5. Leading cause of acute liver failure in the U.S. Hepatotoxic drugs
  6. An autoimmune disease that attacks the nicotinic receptors in skeletal muscle
  7. An opioid antagonist that works to quickly reverse CNS and respiratory depression Myasthenia Gravis Naloxone (Narcan)
  8. How the drug affects the body Pharmacodynamics
  9. Term for the amount of drug that reaches systemic circulation. Often affected by route of administra- tion Bioavailability
  10. Symptoms for this syndrome include confusion, irri- Serotonin tability, tachycardia, hypertension, diaphoresis, and is caused by having too much of this "happy" sub- stance

Used in the treatment of non-hypovolemic hypoten- Norepinephrine or sion phenyleprine

  1. Drug used for acute management of seizures Lorazepam
  2. Used for treatment of beta-blocker overdose Glucagon
  3. Used in treatment of opioid use disorder. May cause Methadone QT prolongation.
  4. This opioid analgesic is used for treatment of post-op shivering or rigors Meperidine
  5. Antiseizure medication that carries Black Box warn- Carbamazepine ings for severe skin reactions such as SJS
  6. Drug class used to treat extra-pyramidal symptoms Anticholinergics
  7. Cause of menstrual-associated migraines Drops in estrogen levels
  8. Chronic use may cause amotivational syndrome or hyperemesis synrome Marijuana (THC)
  9. Deadly bacterial toxin used in prevention of chronic Botox (Botulinum toxin) migraine headaches
  10. Neostigmine is a medication used to treat what dis- Myasthenia Gravis order/disease?
  11. Myasthenia Gravis is an autoimmune disorder that may cause what symptom? Diflculty swallowing
  12. True or false: in order for a medication to affect the TRUE CNS, it must be able to cross the blood brain barrier?
  1. A major goal in treating Parkinson's Disease is to restore what in the brain? Dopamine
  2. Common side effects of dopaminergics? Sleep attacks, hallucinations, confusion
  3. Which medication is appropriate in the treatment of Haloperidol acute psychosis?
  4. After being treated with a first-generation antipsy- chotic, the patient develops difficulty speaking and chewing likely due to which adverse reaction?
  5. Which medication can help manage daily panic at- tacks? Tardive Dyskinesia SSRIs
  6. Cholinesterase inhibitors are used in the treatment Alzheimer's Disease of what condition?
  7. True or false: anticonvulsants are only used to treat FALSE seizure disorders?
  8. This antiseizure medication is also used for prophy- Topiramate lactic treatment of migraines:
  9. This anti-seizure medication is also an anti-arrhyth- Phenytoin (Dilantin) mic:
  10. Which antiseizure medication has a Black Box warn- Carbamazepine (Tegetrol) ing for blood dyscrasias and serious dermatologic reactions?
  11. Which agent should you try first to treat an early onset migraine? NSAIDs

TRUE OR FALSE: angina pain is caused by cardiac ischemia?

  1. All patients with angina should receive this medica- Aspirin tion to reduce mortality?
  2. Lifestyle modifications to reduce cardiac risk in- clude:
  3. a patient with heart failure that has anginal pain with walking and slight limitation of activity is what class?
  4. A patient is taking HCTZ (hydrochlorothiazide) for HTN. What lab is most important to monitor? stop smoking, daily exer- cise, weight loss (at least 10 pounds) II potassium (K)
  5. TRUE OR FALSE: one primary mechanism that wors- TRUE ens heart failure is cardiac remodeling?
  6. Which class of medication is indicated in patients post MI to precent cardiac remodeling?
  7. TRUE OR FALSE: when treating hyperlipidemia, cal- culating ASCVD risk will help to determine treat- ment?
  8. Which class of medication is contraindicated in pa- tients with liver failure?
  9. Which anticoagulant has the quickest onset of ac- tion? ACE inhibitors TRUE HMG-CoA inhibitors (statins) heparin
  10. thrombocytopenia

Patients receiving heparin are at risk for what ad- verse reaction?

  1. Why would heparin and warfarin be given together? warfarin has a delayed ettect
  2. All of the following could increase a patient's ability herbal supplements, aspirin, to bleed:
  3. Factor Xa levels may be monitored for patient's on this medication?

TPA

low molecular weight heparin

  1. Which blood pressure medication can be taken dur- beta blockers ing pregnancy?
  2. after a hip replacement, what drug is often used to prevent DVT?
  3. A patient started on warfarin for A-fib should be taught that... enoxaparin the INR should be between 2 - 3
  4. What is not true about epoetin alfa? treats patients with perni- cious anemia
  5. Pernicious anemia is due to deficiency of B
  6. Lab monitoring for iron deficiency anemia include the following reticulocyte count in 1 week, TIBC in 4 weeks, Hgb/Hct/ferritin in 4 weeks
  7. Which class of antidiabetic medication is contraindi- metformin cated in CKD stage 4, 5
  8. she will be switched to insulin during pregnancy
  1. Your male patient on testosterone has had a 7 pound weight gain and needs early refill on testos- terone, you suspect?
  2. What should you avoid while taking the antibiotic metronidazole (Flagyl) to avoid adverse effects? Do you smoke cigarettes? Hx of DVT/PE? Hx of hysterecto- my? he is using more than pre- scribed Alcohol
  3. What medication class can be used to treat BPH? Alpha blockers
  4. Why would we recommend for a patient to take an aspirin daily? Stroke, MI, PE prevention
  5. What is a big side effect of too much aspirin? Bleeding
  6. What should you monitor closely for an anemic pa- tient getting epoetin? Blood pressure (HTN)
  7. What is the black box warning for epoietis-stimulat- They can cause tumors ing agents (ESAs)
  8. If a patient is diagnosed with angina, what medica- tions should they take?
  9. If you have someone who wants to self-donate, what would we prescribe to them to stimulate red blood cells? aspirin, statins, nitro Epoetin WITH iron
  10. If prescribing iron, what labs do we want to get and Reticulocyte count within 1 how long out should we get them? week TIBC, H&H, ferritin - 4 weeks
  1. What education should we provide to someone needing iron replacement?
  2. In a patient with pernicious anemia receiving Vit B12, what should we monitor? Take on an empty stomach with orange juice (vit. C helps with absorption) and it can cause GI upset Potassium (hypokalemia can occur within first two days)
  3. How long does it take NPH to take effect? 60 - 90 minutes
  4. What is the biggest side effect to monitor for when treating diabetics with insulin or oral agents?
  5. Why can beta blockers and alcohol not be taken together?
  6. If we are switching a patient from NPH to glargine, what do we need to do with the glargine dosing? Hypoglycemia (tachycardia, diaphoresis) Masks signs of hypoglycemia Decrease by 20% to prevent hypoglycemia
  7. What to monitor when starting metformin? Renal function tests
  8. Why are gliptins different from other anti-diabetic medications? They act on the incretin sys- tem (indirectly increasing in- sulin production)
  9. How do GLP- 1 agonists work? Directly bind to receptors in pancreas
  10. What are the NYHA stage classifications for HF? Stage 1 - mild symptoms Stage 2 - angina with exer- tion Stage 3 - severe symptoms w/minimal or no activity
  1. What can happen if you abruptly stop taking ba- clofen? because they cross over the blood brain barrier hallucinations
  2. Who do we give baclofen to? Spasticity patients - MS, SCIs, cerebral palsy
  3. What is Rivastigmine? For alzheimer's disease - transdermal patch changed daily
  4. If a patient has frequent migraines, what meds can we give for prevention?
  5. If prescribing oxycodone and a patient states that this medication does not work for them anymore, what would you do? Propranolol (not for asthmat- ics), topamex change to something stronger/longer acting
  6. What can methadone change physiologically? QT prolongation
  7. What is the biggest side effect of first generation antipsychotics?
  8. If a patient is being switched from an MAOI to an SSRI, what needs to happen? Tardive dyskinesia stop one for two weeks be- fore starting the other
  9. What kind of drug should be given to someone who SSRIs suffers from panic attacks?
  10. If giving HRT for postmenopausal women, which dosing preparation should we utilize? Transdermal - less side ettects
  1. Oral contraceptive choice for a teenage girl who is noncompliant with daily pills? Medroxy-progesterone ac- etate (depo)
  2. What should you do for a women on an OC who has switch her to a progesterone a major surgery coming up? only medication to lower risk of clots
  3. What do we prescribe androgen therapy for? If they Hypogonadism patients - start gaining weight, why is this a concern? check levels they may not be receiving a high enough dose
  4. How do we know if a BPH medication is effective? Easier urination