OB Exam 1 Study Guide: Pregnancy Signs & Body Changes, Study Guides, Projects, Research of Obstetrics

This comprehensive study guide covers key concepts related to pregnancy, including signs and symptoms, changes in the reproductive system, and physiological adaptations during pregnancy. It provides a detailed overview of subjective, probable, and diagnostic signs of pregnancy, along with explanations of various anatomical and physiological changes that occur in the uterus, cervix, ovaries, vagina, and breasts. The guide also discusses common gastrointestinal and cardiovascular changes experienced during pregnancy, including morning sickness, constipation, and heartburn. It emphasizes the importance of understanding these changes for effective prenatal care and management.

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OB Exam 1 Study Guide
Exam 1 OB
Signs of Pregnancy pg. 363
Subjective (Presumptive) Changes
The subjective changes of pregnancy are the symptoms the woman experiences and reports. Because
they can be caused by other conditions, they cannot be considered proof of pregnancy
Amenorrhea, absence of menses, is the earliest symptom of pregnancy (with regular periods). It is not
a reliable sign of pregnancy by itself, but if it were accompanied by consistent nausea, fatigue, breast
tenderness, and urinary frequency, pregnancy would be very likely.
Morning sickness - Nausea and vomiting that occurs early in the day (1st Trimester)
-Women who experience NVP often have a more favorable pregnancy outcome than those who
do not.
Excessive fatigue (1st & 3rd trimester)
Urinary frequency as the enlarging uterus presses on the bladder (1st and 3rd trimester)
Breast changes (tenderness)
Quickening (feels like gas pains and is the moment in pregnancy when the women starts to feel/perceive
fetal movements in the uterus), occurs 16-20 weeks after the LMP
Objective (Probable) Changes
An examiner can perceive the objective changes that occur in pregnancy. Because these changes can
have other causes, they do not confirm pregnancy.
Changes noted in the uterus and vagina during pregnancy within the first three months of pregnancy
-Softening of the cervix (Goodell’s sign)
-Dark violet coloration of cervix, vagina, and vulva (Chadwick’s sign)
-Softening of lower part of uterus, the isthmus (Hegar’s sign)
-An ease in flexing of the body of the uterus against the cervix (McDonald’s Sign)
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OB Exam 1 Study Guide

Exam 1 OB

Signs of Pregnancy pg. 363 Subjective (Presumptive) Changes

- The subjective changes of pregnancy are the symptoms the woman experiences and reports. Because they can be caused by other conditions, they cannot be considered proof of pregnancy - Amenorrhea, absence of menses, is the earliest symptom of pregnancy (with regular periods). It is not a reliable sign of pregnancy by itself, but if it were accompanied by consistent nausea, fatigue, breast tenderness, and urinary frequency, pregnancy would be very likely. - Morning sickness - Nausea and vomiting that occurs early in the day (1st^ Trimester) - Women who experience NVP often have a more favorable pregnancy outcome than those who do not. - Excessive fatigue (1st^ & 3 rd^ trimester) - Urinary frequency as the enlarging uterus presses on the bladder (1st^ and 3 rd^ trimester) - Breast changes (tenderness) - Quickening (feels like gas pains and is the moment in pregnancy when the women starts to feel/perceive fetal movements in the uterus), occurs 16-20 weeks after the LMP Objective (Probable) Changes - An examiner can perceive the objective changes that occur in pregnancy. Because these changes can have other causes, they do not confirm pregnancy. - Changes noted in the uterus and vagina during pregnancy within the first three months of pregnancy - Softening of the cervix ( Goodell’s sign ) - Dark violet coloration of cervix, vagina, and vulva ( Chadwick’s sign ) - Softening of lower part of uterus, the isthmus ( Hegar’s sign ) - An ease in flexing of the body of the uterus against the cervix ( McDonald’s Sign )

- Progressive uterine enlargement - Know o The fundus of the uterus is palpable just above the symphysis pubis at about 10- weeks’ gestation o At the level of the umbilicus at 20 to 22 weeks’ gestation o Between 24-34 weeks the height of the fundus correlates with the weeks of gestation o Note: Woman can have other things growing here that aren’t a baby such as fibroids - Enlargement of the abdomen (2nd^ Trimester she said this is when the uterus becomes an abdominal organ) o Braxton-Hicks contractions can be palpated most commonly after the 28 th^ week. Also termed false labor. o Uterine Soufle may be heard when the examiner auscultates the abdomen over the uterus. Soft blowing sound at the same time as the maternal pulse. - Funic souflé is the soft blowing sound of the blood pulsating through the umbilical cord which occurs at the same time as the fetus’s heart rate. - Changes in Pigmentation (linea nigra, chloasma and striae) - Fetal outline may be identified by palpation in many pregnant women after 24 weeks’ gestation - Ballottement is the passive fetal movement elicited when the examiner inserts two gloved fingers into the vagina and pushes against the cervix. This action pushes the fetal body up and as it falls back the examiner feels a rebound. - Pregnancy test - A positive hCG test is not necessarily and indicator of pregnancy because it can indicate molar masses and/or cancer, while low levels are associated with an ectopic pregnancy Diagnostic (Positive) Changes - The positive signs of pregnancy are completely objective, cannot be confused with a pathologic state, and offer conclusive proof of pregnancy - Fetal heartbeat: detectable by Doppler ultrasound as early as 10-12 weeks of pregnancy - Fetal movement: detected by echocardiography or transvaginal sonography but palpable after about 20 weeks of pregnancy - Visualization of the fetus by ultrasound examination confirms a pregnancy. The gestational sac can be observed by 4-5 weeks of gestation. Transvaginal ultrasound has been used to detect a gestational sac as early as 10 days after implantation. Fetal heart activity by 6-7 weeks. Reproductive System pg. 365 Uterus

  • The change is primarily the result of the enlargement (hypertrophy) of the preexisting myometrial cells in response to the stimulating influence of estrogen and the distention caused by the growing fetus.
  • Shows progressive growth; moves from an oval shape to a globular shape and it starts looking like a light bulb.
  • Hegar’s sign: softening of the lower uterine segment
  • Braxton-Hicks contractions: irregular uterine contractions (false contractions) that begin around the 4 th month of pregnancy and can be mistaken for true labor contractions. These contractions have no effect on the cervix.
  • Leopold’s maneuvers: feeling and palpating the abdomen to evaluate the position and presentation of the fetus
  • By 20 weeks gestation, the fundus, or top of the uterus, is at the level of the umbilicus and measures 20 cm.
  • The fundus reaches its highest level, at approximately 36 weeks, when it reaches the xiphoid process. Because it pushes against the diaphragm, many women experience shortness of breath.
  • Manipulating the uterus to determine the position of the baby - Fundus: the top of the uterus - Isthmus: Middle of the uterus
  • Remain sited upright after eating, avoid spicy foods, eat in small portions
  • Hemorrhoids frequently develop in late pregnancy from constipation and from pressure on vessels below the level of the uterus.
  • High fiber diet and increase fluids to prevent this
  • The emptying time of the gallbladder is prolonged during pregnancy as a result of smooth muscle relaxation from progesterone. This, coupled with the elevated levels of cholesterol in the bile, can predispose the woman to gallstone formation. - If n/v persists past the first trimester = hyperemesis gravidarum Hyperemesis Gravidarum - Persistent and severe nausea and vomiting - Can be fatal - Can cause weight loss (which is malnutrition for the fetus and may cause IUGR), fluid and electrolyte imbalance and dehydration. Dehydration causes uterine contraction, hence is risking placing the mother in preterm labor. Would place on IV on this mom and load her with fluids. Cardiovascular
  • Heart position - shifts upward in transverse position
  • Heart increases in size because its working harder
  • Blood volume increases, as it is needed to provide adequate hydration to fetal and maternal tissues, to supply blood flow to perfuse the enlarging uterus, and to provide a reserve to compensate for blood loos at birth and during postpartum.
  • Anemia includes hemoglobin of less than 10, 3.5 million RBCs or a normal morphology with central pallor.
  • Cardiac output increases & Stroke volume increases
  • The pulse may increase by as many as 10 to 15 beats per minute between 14 to 20 weeks of gestation and persists to term
  • The blood pressure decreases slightly, reaching its lowest point during the second trimester. It gradually increases to near pre-pregnant levels by the end of the third trimester.
  • The enlarging uterus puts pressure on pelvic and femoral vessels, interfering/impeding with returning blood flow and causing stasis of blood in the lower extremities. This condition may lead to dependent edema and varicosity of the veins in the legs, vulva, and rectum (hemorrhoids) in late pregnancy. This increased blood volume in the lower legs may also make the pregnant woman prone to postural hypotension.
  • When the pregnant woman lies supine, the enlarging uterus may press on the vena cava, thus reducing blood flow to the right atrium, lowering blood pressure, and causing dizziness, pallor, palpitations, and clamminess. The enlarging uterus may also press on the aorta and its collateral circulation. This condition is called supine hypotensive syndrome/ vena caval syndrome/ aortocaval compression.
  • It can be corrected by having the woman lie on her left side or by placing a pillow or wedge under her right hip. - Your BP should not increase in pregnancy abnormal -> can be indicative of pre-eclampsia or PIH Hematologic
  • Plasma volume increases & RBC volume increases
  • Because the plasma volume increase (50%) is greater than the erythrocyte increase (30%), the hematocrit, which measures the concentration of red blood cells in the plasma, decreases slightly. This decrease is referred to as the physiologic anemia of pregnancy (pseudoanemia).
  • Vitamins and supplements help to prevent this
  • Hemoglobin decreases (take supplements such as iron)
  • Leukocytosis during pregnancy has no known cause but it is a normal finding. 5,600 to 12,200/mm3. Which can increase up to 25,000/mm3 or higher. - Both fibrin and plasma fibrinogen levels increase during pregnancy. Although the blood-clotting time of the pregnant woman does not differ significantly from that of the non-pregnant woman, clotting factors VII, VIII, IX, and X increase; thus, pregnancy is a somewhat hypercoagulable state. These changes, coupled with venous stasis in late pregnancy, increase the pregnant woman’s risk of developing venous thrombosis.

Respiratory

  • Enlarging uterus presses upward on diaphragm causing difficulty in breathing, elevating the diaphragm
  • Lung expansion may decrease
  • Some hyperventilation and difficulty in breathing may occur (Fatigue, SOB, dyspnea)
  • Nasal stuffiness and epistaxis (nosebleeds) may also occur because of estrogen-induced edema, hypersecretion of mucus, and vascular congestion of the nasal mucosa.
  • Increase maternal oxygen requirements
  • 10 to 12L oxygen can be given without a doctor’s order – not only does the mom need oxygen but the fetus does too Urinary - During the first trimester, the enlarging uterus is still a pelvic organ and presses against the bladder, producing urinary frequency. This symptom decreases during the second trimester, when the uterus becomes an abdominal organ and pressure against the bladder lessens. Frequency reappears during the third trimester, when the presenting part descends into the pelvis and again presses on the bladder, reducing bladder capacity, contributing to hyperemia, and irritating the bladder. - Infections
  • R/t sluggishness of the urine
  • Make sure is drinking a lot of fluids to prevent infections - Glomerular filtration rate increases to meet the increase need of the circulatory system. Glycosuria may be normal or may indicate gestational diabetes, so it always warrants further testing. - 1st and 3rd trimester is when women usually have urinary frequency Skin and Hair (Integumentary) - Stimulated by increased estrogen, progesterone, and α-melanocytic-stimulating hormone levels. Pigmentation of the skin increases primarily in areas that are already hyper pigmented: the areolae, the nipples, the vulva, and the perianal area. - The skin in the middle of the abdomen may develop a pigmented line, the linea nigra, which usually extends from the pubic area to the umbilicus or higher - Facial chloasma (melasma gravidarum), also known as the “mask of pregnancy,” a darkening of the skin over the forehead and around the eyes, may develop. Melasma is more prominent in dark-haired women and is aggravated by exposure to the sun. Fortunately, it fades or becomes less prominent soon after childbirth when the hormonal influence of pregnancy subsides. - Striae (striae gravidarum when they result from pregnancy), or stretch marks, may appear on the abdomen, thighs, buttocks, and breasts. They result from reduced connective tissue strength because of elevated adrenal steroid levels. - Vascular spider nevi, small, bright-red elevations of the skin radiating from a central body, may develop on the chest, neck, face, arms, and legs. They may be caused by increased subcutaneous blood flow in response to elevated estrogen levels. To avoid this: - Elevate both legs when sitting or lying down - Avoid prolonged standing or sitting - Resting in the left lateral position - Walking daily for exercise Musculoskeletal - Calcium: needs increase - Magnesium: needs increase - Pelvic joints: more pliable The joints of the pelvis relax somewhat because of hormonal influences. The result is often a waddling gait.

- As the pregnant woman’s center of gravity gradually changes, the lumbar spinal curve becomes accentuated (lordosis), and her posture changes. This posture change compensates for the increased weight of the uterus anteriorly and frequently results in low backache Central Nervous System - Pregnant women frequently describe decreased attention, concentration, and memory during and shortly after pregnancy, but few studies have explored this phenomenon. Endocrine Thyroid

  • The thyroid gland often enlarges slightly during pregnancy because of increased vascularity and hyperplasia of glandular tissue. Women with low thyroid levels (thyroid insufficiency) may compromise fetal neurologic development. Pituitary
  • Pregnancy is made possible by the hypothalamic stimulation of the anterior pituitary gland.
  • Follicle-stimulating hormone (FSH), which stimulates ovum growth, and luteinizing hormone (LH), which brings about ovulation. Stimulation of the pituitary also prolongs the ovary’s corpus luteal phase. This maintains the endometrium in case conception occurs.
  • Prolactin, another anterior pituitary hormone, is responsible for initial lactation.
  • The posterior pituitary secretes vasopressin (antidiuretic hormone) and oxytocin. Vasopressin causes vasoconstriction, which results in increased blood pressure; it also helps regulate water balance.
  • Oxytocin promotes uterine contractility and stimulates ejection of milk from the breasts (the letdown reflex) in the postpartum period. Pancreas
  • The pregnant woman has increased insulin needs, and the pancreatic islets of Langerhans, which secrete insulin, are stressed to meet this increased demand. Any marginal pancreatic function quickly becomes apparent, and the woman may show signs of gestational diabetes mellitus (GDM). Hormones in pregnancy: Human Chorionic Gonadotropin (hCG)
  • This hormone stimulates progesterone and estrogen production by the corpus luteum to maintain the pregnancy until the placenta is developed sufficiently to assume that function. Human Placental Lactogen (hPL)
  • Also called human chorionic somatomammotropin, human placental lactogen (hPL) is produced by the syncytiotrophoblast.Human placental lactogen is an antagonist of insulin; it increases the amount of circulating free fatty acids for maternal metabolic needs and decreases maternal metabolism of glucose to favor fetal growth. Estrogen
  • Estrogen stimulates uterine development to provide a suitable environment for the fetus. It also helps develop the ductal system of the breasts in preparation for lactation. Progesterone
  • Progesterone plays the greatest role in maintaining pregnancy. It maintains the endometrium and inhibits spontaneous uterine contractility, thus preventing early spontaneous abortion. Progesterone also helps develop the acini and lobules of the breasts in preparation for lactation. Relaxin
  • Relaxin inhibits uterine activity, diminishes the strength of uterine contractions, aids in the softening of the

cervix, and has the long-term effect of remodeling connective tissue, which is necessary for the uterus to accommodate pregnancy Prostaglandins

  • Prostaglandins are lipid substances that can arise from most body tissues but occur in high concentrations in the female reproductive tract and are present in the decidua (endometrium) during pregnancy.
  • They are responsible for maintaining reduced placental vascular resistance. Decreased prostaglandin levels may contribute to hypertension and preeclampsia. Prostaglandins may also play a role in the complex biochemistry that initiates labor.
  • At the beginning of pregnancy, the synthesis of estrogen and progesterone is ensured by the corpus luteum that is maintained by hCG. The activity of the corpus luteum decreases with the beginning of the 8 th^ week in order to be entirely replaced by the placenta at the end of the 1 st^ trimester.
  • The corpus luteum is what produces the hormones before the placenta takes over. Metabolism - Taking iron supplements is essential for fetal growth and brain development and in prevention of maternal anemia. It is needed to form new blood cells for the expanded maternal blood volume. 27 mg of ferrous iron per day is recommended. - An increase in folic acid is essential before pregnancy and in the early weeks of pregnancy to prevent neural tube defects in the fetus. 400 to 800 mcg of folic acid per day are recommended. - Protein in diet should be increased from 60 to 80/g day, while calories should be increased by 300/day from the daily-recommended intake of 1800 to 2200. Weight
  • The recommended total weight gain during pregnancy for a woman of normal weight before pregnancy is 11.5 to 16 kg (25 to 35 lb)
  • For women who were overweight before becoming pregnant, the recommended gain is 6.8 to 11.5 kg ( to 25 lb).
  • Women with obesity are advised to limit weight gain to 5 to 9 kg (11 to 20 lb).
  • Underweight women are advised to gain 12.7 to 18.1 kg (28 to 40 lb)
  • During the first trimester, women whose pre-pregnancy weight is within the normal weight range, weight gain of about 3.5 to 5 lb is considered normal. For underweight women, weight gain should be at least 5 lb. For over-weight women, weight gain should be 2 lb. During the second and third trimesters, for women whose pre-pregnancy weight is within the normal weight range, weight gain should be about 1 pound per week, for those underweight then over 1 pound per week and for those over-weight a weight gain of less than 1 pound a week. Water Metabolism
  • The increased level of steroid sex hormones affects sodium and fluid retention.
  • The extra water is needed for the fetus, the placenta, amniotic fluid, and the mother’s increased blood volume, interstitial fluids, and enlarged organs. Nutrient Metabolism
  • Low sodium, adequate calories, increased protein
  • The fetus makes its greatest protein and fat demands during the second half of pregnancy, doubling in weight during the last 6 to 8 weeks. Psychological Response to Pregnancy

The Father

  • Initially, expectant fathers may feel pride in their virility, which pregnancy confirms, but also have many of the same ambivalent feelings as expectant mothers. The extent of ambivalence depends on many factors, including the father’s relationship with his partner, his previous experience with pregnancy, his age, his economic stability, and whether the pregnancy was planned.
  • They also share the experiences of pregnancy and birth with their partners First Trimester - After the initial excitement attending the announcement of the pregnancy, an expectant father may begin to feel left out. He may be confused by his partner’s mood changes. He might resent the attention she receives and her need to modify their relationship as she experiences fatigue and possibly a decreased interest in sex. He might also be concerned about what kind of father he will be. Second Trimester - The father’s role in the pregnancy is still vague, but his involvement may increase as he watches and feels fetal movement and listens to the fetal heartbeat during a prenatal visit. For many men, seeing their infant on ultrasound is an important experience in accepting the reality of pregnancy - The father-to-be’s anxiety is lessened if both parents agree on the paternal role the man is to assume Third Trimester - If the couple’s relationship has grown through effective communication of their concerns and feelings, the third trimester is often a rewarding time - If the father has developed a detached attitude about the pregnancy, however, it is unlikely he will become a willing participant, even though his role becomes more obvious. Concerns and fears may recur. The father may worry about hurting the unborn baby during intercourse or become concerned about labor and birth. He may also wonder what kind of parents he and his partner will be. Couvade
  • Couvade has traditionally referred to the observance of certain rituals and taboos by the male to signify the transition to fatherhood. This observance affirms his psychosocial and biophysical relationship to the woman and child. More recently the term has been used to describe the unintentional development of physical symptoms such as fatigue, increased appetite, difficulty sleeping, depression, headache, or backache by the partner of a pregnant woman. Men who demonstrate couvade syndrome tend to have a higher degree of paternal role preparation and be involved in more activities related to this preparation. Siblings
  • Bringing a new baby home often marks the beginning of sibling rivalry. The siblings view the baby as a threat to the security of their relationships with their parents
  • Because they do not have a clear concept of time, young children should not be told too early about the pregnancy
  • The mother may let the child feel the baby moving in her uterus, explaining that the uterus is “a special place where babies grow.” The child can help the parents put the baby clothes in drawers or prepare the baby’s room.
  • Consistency is important in dealing with young children. They need reassurance that certain people, special things, and familiar places will continue to exist after the new baby arrives Grandparents
  • Younger grandparents leading active lives may not demonstrate as much interest as the young couple would like.
  • In other cases, expectant grandparents may give advice and gifts unsparingly. For grandparents, conflict may be related to the expectant couple’s need to feel in control of their lives, or it may stem from events signaling changing roles in the grandparents’ own lives (e.g., retirement, financial concerns, menopause, or death of a friend).
  • Some parents of expectant couples may already be grandparents with a developed style of grand parenting.
  • Clarifying the role of the helping grandparent ensures a comfortable situation for all. Cultural Values and Pregnancy
  • Cultures have a universal tendency to create ceremonial rituals or rites around important life events. The
  • Cause - Elevated estrogen levels
  • Management - Avoid decongestants! - Use humidifiers, cool mist vaporizers, and normal saline drops 4. Ptyalism (the excessive spitting in pregnancy)
  • Cause - Unknown
  • Management - Perform frequent mouth care - Chew gum or suck hard candy 5. Nausea and vomiting
  • Cause - Unknown; although some books say its because of the hormones
  • Management - Avoid foods or smell that exacerbate condition - Eat dry crackers or toast before arising in the morning - Eat small, frequent meals Common Discomforts of Pregnancy in 2 nd^ **Trimester:
  1. Shortness of breath**
  • Cause - Growing fetus puts pressure on the diaphragm
  • Management - Use extra pillows at night to keep more upright - Limit activity during the day to what they are comfortable with or less 2. Heartburn – Pyrosis
  • Cause - Displacement of the stomach & intestines by growing fetus
  • Management - Eat small, more frequent meals - Use antacids - Avoid overeating and use of spicy foods 3. Varicosities
  • Cause - Weight of the uterus, which causes pooling and engorgement of veins in lower extremities - Heredity, age, obesity - Increased vascularity
  • Management - Rest in sims’ position - Elevate legs regularly - Avoid crossing legs - Avoid tight stockings - Avoid long periods of standing 4. Leukorrhea (white vaginal discharge): If it is offensive: greenish/pink/odor = get medical tx
  • Cause - Increased estrogen levels
  • Management - Take daily bath or shower

- HOT GIRL PANTIES HAVE TO GO! Wear cotton underwear (to absorb extra moisture) - Do not douche!!! (you’ll wash away natural bacteria) 5. Backache

  • Cause - Lumber lordosis that develops to maintain balance on later pregnancy
  • Management - Wear shoes with low heals - Walk with pelvis tilted forward - Use firmer mattress - Perform pelvic rocking or tilting - Mild discomfort = OKAY … severe discomfort may indicate premature labor 6. Flatulence
  • Cause - Decreased gastric motility - Pressure of growing uterus on large intestine
  • Management - Avoid gas-forming foods (beans, broccoli, oatmeal) - Chew food thoroughly - Engage in regular daily exercises - Maintain regular bowel routine 7. Leg cramps
  • Cause - Decrease serum calcium levels - Increase serum phosphate - Interference with circulation
  • Management - Extend affected leg and dorsiflex the foot - Elevated lower legs frequently - Apply heat to muscles - Evaluate diet and make sure she is getting enough electrolytes 8. Carpal Tunnel Syndrome
  • Cause - Compression of the medial nerve of the wrist - Weight gain and edema may also contribute
  • Management - Avoid aggravating hand movements - Elevate affected arm - Wear splints 9. Faintness
  • Cause - Pooling of blood in lower extremities - Anemia - Supine orthostatic hypotension
  • Management - Rise slowly from sitting to standing / avoid lying on her back - Evaluate H&H - Avoid hot and stuffy environments 10. Mood swings
  • Cause
  • Length of pregnancy (to help determine the length of the next one; if you had babies at 28 weeks you may deliver the next one early)
  • Type of birth (C-sections, vaginal) - Once a section is not always a C-section. It is safer to have a natural birth 2 years after having a C-section.
  • Type of anesthesia used, if any
  • Complications associated with childbirth, if any
  • Neonatal complications
  • Blood type and Rh factor - RH factor affects a mother who is negative. It affects mom when she becomes pregnant from a positive man. When the RH negative mother becomes pregnant, if the baby is positive and the blood gets into her blood stream her body will see that as a foreign body, and her body will build immunity and fight that blood. The first baby will be fine. It affects the next baby because they will be seen as a foreign body so she will keep aborting the rest of her babies. - ( RhoGAM shot is given at 28 weeks to protect her against any Rh-positive red blood cells from the fetus.)
  • Prenatal education classes and resources 3. Gynecologic history
  • Date of last Pap smear; results?
  • Previous infections
  • Previous surgery
  • Age at menarche – regularity, frequency, and duration of menstrual flow
  • History of dysmenorrhea
  • History of infertility
  • Sexual history
  • Contraceptive history 4. Current medical history
  • General health, including nutrition
  • Weight – pre-pregnant and current.
  • Medications and use of herbal medications - interactions can occur
  • Previous or presence use of alcohol, tobacco, or caffeine (these things are teratogenic and can have bad effects on the baby; a baby born to an alcoholic can have fetal alcohol syndrome or come out with seizures/ withdrawal symptoms because the baby wants drug; A baby born to a diabetic may experience hypoglycemia.)
  • Illicit drug use and drug allergies and other allergies - Ex: Thalidomide was given for n/v in pregnancy in the 60's; babies were born without limbs because of the effects of the drug.
  • Potential teratogenic insults to this pregnancy – viral, medications, X-rays, cats at home, surgery - Teratogen= Any biological, physical, chemical, or radioactive agent that causes structural or functioning damage to the fetus
  • Presence of chronic disease conditions such as diabetes, hypertension, cardiovascular, renal, cancer, thyroid disorder
  • Record of Immunizations - Ask about immunization history. For example: screening for rubella is done but not treated until after delivery. Reasons being are because these vaccinations are live viruses. If given during pregnancy, the baby will be born death.
  • With some vaccines the benefit outweighs the risk.
  • Advise pregnant women to avoid live virus vaccines (MMR and varicella) and to avoid becoming pregnant within 1 month of having received one of these vaccines because of the theoretical risk of transmission to the fetus. 5. Past medical history
  • Childhood diseases
  • Past treatment for any disease condition