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Pharmacology and therapeutics NRSG-100 Mott community College UPDATED ACTUAL Questions and CORRECT Answers
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What organ is responsible for most drug metabolism? - CORRECT ANSWER - Liver What is the first-pass effect? - CORRECT ANSWER - Liver metabolizes drug before it reaches circulation What does half-life mean? - CORRECT ANSWER - Time for drug concentration to decrease by half What is the difference between additive and synergistic effects? - CORRECT ANSWER - Additive = normal increase, synergistic = exaggerated effect What is the main risk of beta blockers in asthma? - CORRECT ANSWER - Bronchoconstriction What electrolyte imbalance does furosemide cause? - CORRECT ANSWER - Hypokalemia What electrolyte imbalance does spironolactone cause? - CORRECT ANSWER - Hyperkalemia What lab monitors warfarin? - CORRECT ANSWER - INR What lab monitors heparin? - CORRECT ANSWER - aPTT What is the antidote for warfarin? - CORRECT ANSWER - Vitamin K
What is the antidote for heparin? - CORRECT ANSWER - Protamine sulfate What is a common side effect of nitroglycerin? - CORRECT ANSWER - Headache What is a major risk of ACE/ARB (losartan)? - CORRECT ANSWER - Hyperkalemia What is a sign of digoxin toxicity? - CORRECT ANSWER - Yellow vision What is a side effect of albuterol? - CORRECT ANSWER - Tachycardia What must you do after using inhaled steroids? - CORRECT ANSWER - Rinse mouth What is a risk of theophylline toxicity? - CORRECT ANSWER - Seizures What is the key side effect of long-term omeprazole use? - CORRECT ANSWER - Bone loss What must you do with sucralfate and other medications? - CORRECT ANSWER - Take 2 hours apart What does aluminum hydroxide cause? - CORRECT ANSWER - Constipation + low phosphorus What is misoprostol contraindicated in? - CORRECT ANSWER - Pregnancy What is the major risk of ondansetron? - CORRECT ANSWER - QT prolongation What does metoclopramide cause? - CORRECT ANSWER - EPS (movement disorders)
What must you avoid with metronidazole? - CORRECT ANSWER - Alcohol What is the most important risk of insulin? - CORRECT ANSWER - Hypoglycemia What is the serious risk associated with metformin? - CORRECT ANSWER - Lactic acidosis How should you take levothyroxine? - CORRECT ANSWER - On an empty stomach What is the major risk of PTU? - CORRECT ANSWER - Liver damage What is a major risk of oral contraceptives? - CORRECT ANSWER - Blood clots What should be avoided with sildenafil? - CORRECT ANSWER - Nitrates What is a side effect of tamsulosin? - CORRECT ANSWER - Orthostatic hypotension What are the side effects of oxybutynin? - CORRECT ANSWER - Dry mouth, constipation What are the side effects of leuprolide? - CORRECT ANSWER - Menopause symptoms, bone loss What are the major risks of methotrexate? - CORRECT ANSWER - Liver damage + bone marrow suppression What supplement should be taken with methotrexate? - CORRECT ANSWER - Folic acid What is the main danger of opioids? - CORRECT ANSWER - Respiratory depression
What is the main concern with diuretics? - CORRECT ANSWER - Potassium imbalance What is the main risk associated with anticoagulants? - CORRECT ANSWER - Bleeding What are the side effects of anticholinergics? - CORRECT ANSWER - Dry mouth, constipation What is the main risk of insulin? - CORRECT ANSWER - Hypoglycemia