Pharmacy Calculation Formulas: Density, Half-Life, Shelf Life, Dilution, Isotonicity, Exams of Pharmacy

Various calculation formulas used in pharmacy, including density, half-life, shelf life, dilution, henderson-hasselbalch equation, isotonicity, sce, suppository formulation, %error, isosmotic and osmolar solutions.

Typology: Exams

2023/2024

Available from 03/30/2024

DrShirleyAurora
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Pharmacy calculation formulas
Density -
D=m/v
half life equation -
t1/2 = 0.693/k
Shelf life equation -
t90%=0.105/k
dilution equation -
C1V1=C2V2
dilution of liquid formulation -
amount of drug (mg)/quantity (mL) X DF = amount (mg)/dose (mL)
Henderson-Hasselbalch equation -
pH = pKa + log [salt]/[acid]
Isotonicity -
% adjusting= [0.52-[(%A x FD1%A)+(%B x FD1%B)....]/FD1% adjusting
SCE -
% adjusting= [0.9-[(%A x SCEa)+(%B x SCEb)....]/SCE adjusting
suppository formulation -
weight base for Y suppositories=[calibration-(dose (g)/DV)] x density x Y
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Pharmacy calculation formulas

Density - D=m/v half life equation - t1/2 = 0.693/k Shelf life equation - t90%=0.105/k dilution equation - C1V1=C2V dilution of liquid formulation - amount of drug (mg)/quantity (mL) X DF = amount (mg)/dose (mL) Henderson-Hasselbalch equation - pH = pKa + log [salt]/[acid] Isotonicity - % adjusting= [0.52-[(%A x FD1%A)+(%B x FD1%B)....]/FD1% adjusting SCE - % adjusting= [0.9-[(%A x SCEa)+(%B x SCEb)....]/SCE adjusting suppository formulation - weight base for Y suppositories=[calibration-(dose (g)/DV)] x density x Y

%error formula - %error=(sensitivity/amount weighed) x 100 isosmotic solution - % adjusting/Ciso adjusting = 1-((%A/CisoA)+(%B/CisoB)......) Ciso of a substance - Ciso=(0.9/SCE of the substance) osmolar solution - 1 Osm/L solution Osmolal solution - 1 Osm/Kg solution osmole - amount of solute that dissociates in solution to form 1 mole of osmotically active particles 1 mole NaCl= 2 Osm particles