Physiologic Changes of Aging, Lecture notes of Medicine

A comprehensive overview of the various physiological changes that occur in the human body as a person ages. It covers a wide range of systems, including the neurological, sensory, cardiovascular, respiratory, gastrointestinal, genitourinary, musculoskeletal, integumentary, immune, and endocrine systems. The document highlights the specific changes that take place in each of these systems, such as decreased cardiac output, reduced lung volume, diminished taste and smell, increased urinary frequency, and loss of bone density. Additionally, the document discusses the cognitive changes that can occur with aging, including alterations in personality and memory. This information is crucial for healthcare professionals, caregivers, and individuals interested in understanding the natural aging process and its impact on the human body.

Typology: Lecture notes

2020/2021

Uploaded on 06/15/2022

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PHYSIOLOGIC CHANGES
OF AGING
NEUROLOGICAL CHANGES
-Delirium/ Acute confusion
-Dimentia
-Sundowner’s Syndrome
SENSORY ORGAN CHANGES
-Poor Vision
-Hearing problems
-Loss of Smell
-loss the sense of Touch or
feeling
-Loss of taste
CARDIOVASCULAR CHANGES
-Decrease cardiac output
- Increase arterial stiffness
-decrease heart rate modulation
-Myocardial hypertrophy
-Impaired endothelial function
-Conduction abnormalities
-Cardiac Atrophy
RESPIRATORY SYSTEM
-decrease elastic recoil
-Decrease ciliary function
- Weak thoracic inspiratory and
expiratory muscles
-Less effective inspiration
contractions
-Decrease lung volume
GASTROINTESTINAL CHANGES
-Saliva production decreases
-Tooth loss can lead to GI
problems since almost elders rely
on dentures
- Taste sensation decreases
because taste buds atrophy
-Esophageal motility decreases
-slower stomach motility
- Mass of the liver decreases in
weight and storage capacity
GENITOURINARY CHANGES
-Renal mass becomes smaller
with age
-tubular function decreases
- Changes in the kidney’s
function with aging alter the
renal excretion of drugs.
-increase urinary frequency
-bladder muscle and volume
decrease
-male reproductive system
changes such as: Decreased
testosterone production,
reduced sperm count, smaller
testes, and a need for more
direct physical stimulation to
achieve an erection
-female reproductive system
changes such as: Decreased
estrogen production, reduction
in breast tissue, increase
possibility of vaginitis, vaginal
canal is drier.
MUSCULOSKELETAL CHANGES
-Muscle tremors
-Bones become brittle and can
break easily
-Osteoporosis is a condition that
occurs so frequently
-Bone loss
IMMUNE SYSTEM CHANGES
-increased risk of infection
-Natural antibodies decrease
-greater risk of autoimmune disorders
-Antibody response to antigens
declines
ENDOCRINE CHANGES
-Reduction in hormone
production to regulate
physiology
COGNITIVE CHANGES
-changes in personality
-memory maybe altered by age
- With increasing age, there is more
time needed for problem solving.

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PHYSIOLOGIC CHANGES

OF AGING

NEUROLOGICAL CHANGES

-Delirium/ Acute confusion

-Dimentia

  • Sundowner’s Syndrome SENSORY ORGAN CHANGES
  • Poor Vision
  • Hearing problems
  • Loss of Smell
  • loss the sense of Touch or feeling
  • Loss of taste CARDIOVASCULAR CHANGES
  • Decrease cardiac output
  • Increase arterial stiffness
  • decrease heart rate modulation
  • Myocardial hypertrophy
  • Impaired endothelial function
  • Conduction abnormalities
  • Cardiac Atrophy

RESPIRATORY SYSTEM

  • decrease elastic recoil
  • Decrease ciliary function
  • Weak thoracic inspiratory and expiratory muscles
  • Less effective inspiration contractions
  • Decrease lung volume

GASTROINTESTINAL CHANGES

  • Saliva production decreases
  • Tooth loss can lead to GI problems since almost elders rely on dentures
  • Taste sensation decreases because taste buds atrophy
  • Esophageal motility decreases
  • slower stomach motility
  • Mass of the liver decreases in weight and storage capacity

GENITOURINARY CHANGES

  • Renal mass becomes smaller with age
  • tubular function decreases
  • Changes in the kidney’s function with aging alter the renal excretion of drugs.
  • increase urinary frequency
  • bladder muscle and volume decrease
  • male reproductive system changes such as: Decreased testosterone production, reduced sperm count, smaller testes, and a need for more direct physical stimulation to achieve an erection
  • female reproductive system changes such as: Decreased estrogen production, reduction in breast tissue, increase possibility of vaginitis, vaginal canal is drier.

MUSCULOSKELETAL CHANGES

-Muscle tremors

-Bones become brittle and can

break easily

-Osteoporosis is a condition that

occurs so frequently

-Bone loss

INTEGUMENTARY CHANGES

  • The skin becomes less elastic, drier and more fragile
  • Scalp, pubic and axilla hair thins and loses color
  • Fingernail growth slows and they become thicker and more brittle.
  • Increased proportion of adipose tissue
  • loss in subcutaneous tissue

IMMUNE SYSTEM CHANGES

  • increased risk of infection
  • Natural antibodies decrease
  • greater risk of autoimmune disorders
  • Antibody response to antigens declines

ENDOCRINE CHANGES

  • Reduction in hormone production to regulate physiology

COGNITIVE CHANGES

  • changes in personality
  • memory maybe altered by age
  • With increasing age, there is more time needed for problem solving.