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Proteus mirabilis: Taxonomy, Characteristics, and Pathogenicity, Cheat Sheet of Biology

Saba University School of MedicineBiology

An overview of Proteus mirabilis, a bacterium belonging to the Gammaproteobacteria class of the phylum Proteobacteria. Discovered in 1885 by German pathologist Gustav Hauser, Proteus mirabilis is a gram-negative, rod-shaped, asporogenic bacterium with flagella and fimbriae. It is a part of normal human gut microbiota but can also cause hospital-acquired infections such as urinary tract infections. its taxonomy, morphology, biochemical and cultural properties, antigenic structure, and virulence factors.

Typology: Cheat Sheet

2021/2022

Uploaded on 05/21/2022

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mirabilis
Виконала: Дацко Яна, 9208
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Download Proteus mirabilis: Taxonomy, Characteristics, and Pathogenicity and more Cheat Sheet Biology in PDF only on Docsity!

z

Proteus

mirabilis

Виконала: Дацко Яна, 9208

Рід Proteus

Індол+

Proteus vulgaris Proteus inconstans

Індол –

Proteus mirabilis Proteus hauseri Proteus penneri

Історія 1885 року Proteus mirabilis (та інші види роду Протей) дослідив німецький патолог Густав Хаузер В 2008 році геном Proteus mirabilis повністю розшифрувала Мелані Пірсон

Морфологія o (^) Грамнегативні o (^) Паличкоподібна форма o (^) Аспорогенна o (^) Є фімбрії o (^) Є джгутики o (^) Нема капсули

Антигенна будова

Н-АГ(джгутиковий) К-АГ(капсульний) О-АГ(соматичний)

Феномен роїння на кров'яному агарі

Агар МакКонкі

Тест на індол

Фактори патогенності

  • (^) Джгутики
  • (^) Фімбрії
  • (^) Уреаза
  • (^) Гемолізини
  • (^) Ендотоксини
  • (^) Протеїназа

Патогенез

До несприятливих наслідків

сечокам'яної хвороби відносяться:

  • Гідронефроз
  • Піонефроз
  • Нефрогенна артеріальна гіпертензія
  • Ниркова недостатність
  • Паранефрит

Лікування Антибіотикотерапія: бета- лактами, ампіцилін застосовують найчастіше. Резистентні до: тетрацикліну та нітрофурантоїну.

ДЯКУЮ ЗА УВАГУ!