Psychotropic Medication Management, Exams of Nursing

Detailed information on the management of various psychotropic medications, including latuda, abilify, kava kava, tricyclic antidepressants (tcas), lamotrigine, tegretol, clozaril, lithium, selective serotonin reuptake inhibitors (ssris), bupropion (wellbutrin), and medications for neuropathic pain. It covers topics such as side effects, drug interactions, monitoring parameters, and treatment approaches for conditions like schizophrenia, depression, and substance abuse. The document also discusses ethical considerations, legal aspects, and counseling strategies related to mental health care.

Typology: Exams

2023/2024

Available from 07/31/2024

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PMHNP certification Exam (100 out of 100)
Questions and Answer Elaborations
Which patient is at highest risk for SI
A. 30y/o married AA female with previous SI attempt *1 risk factor
B. 35 y/o single Asian male with previous SI attempt *3 risk factors
C. 38 y/o single AA male who is a manager of a bank *2 risk factors
D. 68 y/o single white male with depression *5 risk factors (age, male, white, depression)
D. 68 y/o single white male with depression *5 risk factors (age, male, white, depression)
Count the risk factors
When interview teenagers (16 y/o) that arrive with their parents what should you do?
interview them separately from parents.
-This helps Build therapeutic rapport with teens by telling them the info is confidential. Parents
may be upset but remember you are advocating for the child.
Which Ethnic group has the highest rate of suicide?
Native Americans
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PMHNP certification Exam (100 out of 100)

Questions and Answer Elaborations

Which patient is at highest risk for SI A. 30y/o married AA female with previous SI attempt *1 risk factor B. 35 y/o single Asian male with previous SI attempt *3 risk factors C. 38 y/o single AA male who is a manager of a bank *2 risk factors D. 68 y/o single white male with depression *5 risk factors (age, male, white, depression) D. 68 y/o single white male with depression *5 risk factors (age, male, white, depression) Count the risk factors When interview teenagers (16 y/o) that arrive with their parents what should you do? interview them separately from parents.

  • This helps Build therapeutic rapport with teens by telling them the info is confidential. Parents may be upset but remember you are advocating for the child. Which Ethnic group has the highest rate of suicide? Native Americans

Example A patient is being treated for schizophrenia with olanzapine. Which of the following is the most common side effect of olanzapine? A. Increased waist circumference B. EPS (not as common in atypical antipsychotics d/t 5HT2A)-receptor antagonism C. Increased Lipids D. Metabolic Syndrome D. Metabolic Syndrome (UMBRELLA ANSWER) Which antipsychotics have the least weight gain? Latuda, Abilify, (also least sedating), Geodon-if patient has metabolic syndrome consider switching to one of the medications above. Or if the patient is overly sedated try switching to ABILIFY Which mood stabilizer have the least weight gain? Lamictal

  • But remember all mood stabilizers cause some weight gain When presented with a question about typical vs atypical antipsychotic the answer is usually to start of a atypical

Key symptoms of Heat Intolerance Hyperthyroidism When T4 and T3 are Low and TSH is high what is the diagnosis (HYPOTHYROIDISM) TSH secretion increased: TSH HIGH à COLD INTERANCE Key symptoms of Cold Intolerance Hypothyroidism Hyperthyroid can mimic Mania Hypothyroid can mimic Depression A patient on depakote complains of RUQ pain and has reddish/brown urine Hepatoxicity

  • Check LFTs Signs of Depakote toxicity

Disorientation, confusion, lethargy You suspect depakote toxicity what do you do? Check

  • LFT
  • Ammonia
  • Depakote Level What herbal supplement can cause hepatoxicity? Kava Kava When taking Kava Kava in combinations with other medications you should caution about Risk of Hepatoxicity and Sedation TCAs carry a risk of Hepatotoxicity Signs of Stevens-Johnson Syndrome
  • fever, mouth pain, swelling, burning eyes, blisters, skin pain two psychotropics known to cause steven johnson syndrome

Which two medications may decrease the risk of suicide? clozaril and lithium Medications that increase lithium level NSAID-ibuprofen, INDOCIN THIAZIDES-hydrochlorithiazide ACE INHIBITORS-lisinopril Ace inhibitors are treatment of choice for? Heart Failure Certain medications are known to increase lithium level, but HOW? by reducing renal clearance When educating a patient about lithium teach them about Hyponatremia Dehydration-hot days, exercise Normal Lithium Level 0.6-1.

Lithium Toxicity 1.5 or above Discontinue and re-order lithium level Lithium level of 1. Monitor for toxicity Labs before starting lithium TSH, BUN, CREATININE, HCG, U/A to check for presence of protein in the urine (4+ protein is concerning for renal impairment)à4+ protein in urine=MONITOR FOR TOXICITY 4+ protein in the urine of a patient on lithium 4+ protein is concerning for renal impairment 4+ protein in urine=MONITOR FOR TOXICITY Lithium side effects hypothyroid, leukocytosis, maculopapular rash, t-wave inversion, Coarse Hand Tremor, GI upset (nausea, vomiting, anorexia)

  • Some of these are also signs of toxicity
  • Bromocriptine (Dopamine D2 agonist). *In question focus on what they are asking for….dopamine agonist vs muscle relaxer Treatment for Serotonin Syndrome Stop Med (1 or more SSRI, SSNRI, TCA, MOAI)
  • Cyproheptadine Triptans Used for MIGRAINES
  • These meds increase serotonin example SUMATRIPTAN patient taking Prozac and started on sumatriptan
  • call PCP to ask them to switch the migraine med if patient already on SUMATRIPTAN do not start antidepressant without talking to PCP

How long do you wait when switching between an SSRI to an MAOI? 2 weeks How long do you wait when switching between Prozac and MAOI? 5 - 6 weeks wash out period What is the first line treatment for depression and why? SSRI-First line treatment for depression due to less risk of injury from OVERDOSE If a cancer patient has depression what should you consider? Treating with a medication with minimal drug/drug side effects like Lexapro Patient with depression worries about sexual dysfunction what would be the medication of choice? Wellbutrin Primary symptoms of depression include fatigue and low energy what med would you chose? Wellbutrin

Ages of onset for schizophrenia in males vs females

  • MALES 18-25 years
  • FEMALE 25-35 years Schizophrenia increases the risk for SUICIDE HIGH RISK OF SI in SCHIZOPHRENIA Just having schizophrenia increases your risk of suicide. MUST ASK ABOUT SI, EVERYTIME (frequency, severity of thoughts) What increases the causes or increases the risk or schizophrenia excessive pruning of synapses
  • inadequate synapse formation,
  • intrauterine insults such as maternal exposure to toxins, viral agents, maternal substance use, maternal illness, maternal malnutrition, fetal oxygen deprivation,
  • first order relative (mom/dad) MRI or PET scan what is seen in schizophrenia EVERYTHING DECREASES EXCEPT VENTRICLES
  • You will see VENTRICULAR ENLARGEMENT Stimulants can potentiate the release of what neurotransmitter? Dopamine which can worsen symptoms of schizophrenia Assertive Community Treatment (ACT) a form of rehabilitation post hospitalization, in home treatment What level of prevention is ACT? Tertiary What adjunctive treatment is important in schizophrenia
  • social skills training
  • Exercise

Circumstantial means that their response goes in circles instead of getting to the point of the question Mental Status-Thought Content includes SI/HI/AH/VH Another name for MMSE Folstein Scale How to assess concentration on MMSE Serial 7s or perform an activity backwards i.e list the days of the week backwards Assess ability to learn new material repeat 3 words after me Assess ability to recall repeat 3 words after 5 minutes

Assess fund of knowledge Who is the president What is a quick and easy way to assess for neurological issues Clock drawing test If patient is unable to draw a clock this indicates Problem with the right hemisphere, cerebrum, or parietal lobe mesolimbic pathway Hyperactivity of dopamine in the this pathway mediates positive psychotic symptoms

  • Antagonism of D2 receptors in this pathway treats positive psychotic symptoms mesocortical pathway
  • Decreased dopamine in the this projection to the dorsolateral prefrontal cortex is postulated to be responsible for negative and depressive symptoms of schizophrenia Nigrostriatal Pathway

Long-term hyperprolactinemia can be associated with what condition osteoporosis Normal Prolactin Level in Men level less than 20ng/ml Normal Prolactin Level in Women less than 25ng/ml Which medication is the highest offender for increasing prolactin Risperdal Acute Dystonia + Treatment neck stiffness, muscle spasm of upper body especially neck/face/tongue

  • Treatment is IM COGENTIN + continue PO COGENTIN for several days

Akathisia + Treatment may mimic anxiety, restlessness, can’t sit still, rocking, pacing

  • First line Treatment is BETA-BLOCKERS like PROPANOLOL (Inderal)
  • Second line treatment is COGENTIN
  • Third line treatment is benzos Beta-Blockers such as Inderal are contraindicated with what type of asthma medication
  • DO NOT GIVE WITH BROCHODIALATOR such as ALBUTERAL this combination can cause bronchospasm akinesia/bradykinesia + treatment A. difficulty initiating movement; slowness of movement
  • Treatment Cogentin PSEUDOPARKINSON or PARKINSONIAN + Treatment caused by dopamine blockade, results in muscle rigidity, mask like facial expression, may look blunted, pill rolling tremors in fingers, shuffling gait, motor slowing