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NurseBernie PTCE STUDY TEST EXAM [236 QUESTIONS AND CORRECT ANSWERS The medication that has an expiration date 12/14 would expire on - CORRECT ANSWER - the last day of December 2014 at midnight in the NDC 4253-4221-11, what is represented by the second set of numbers - CORRECT ANSWER - NDC number is 10 digits long and comprised of three sets of numbers - the 1st set: 4-5 digits and represents the manufacturer - The 2nd set: 3-4 = the product name, strength and dosage form. - The 3rd set: 2 digits = package size A pharmacy technician's scope of practice includes ....- CORRECT ANSWER - answering patients's questions regarding their medications. - Only pharmacists can counsel patients regarding their medications Which act distingushed between legend and nonlegend drugs - CORRECT ANSWER - the Durham Humphrey Amendment - distinguish between prescription and over the counter drugs and prohibits the sale of legend drugs without a prescription The Kefauver- Harris Amendment - CORRECT ANSWER - requires drugs to be proven pure, safe and effective The Orphan Drug Act - CORRECT ANSWER - encourages findings drug treatment for rare diseases The Harrison Narcotin Act - CORRECT ANSWER - limits the transport, manufacture and safe of opium and any of its derivatives. it requires a written prescription to purchase any of the aforementioned drugs. What is the maximum number of refills permitted for a schedule III-V medication - CORRECT ANSWER - Five refills within 6 months, whichever occurs first. therefor a new prescription is required A pharmacy technician receives a prescription that reads 2 gtt AU BID. What will the label placed on the patient's medication read? - CORRECT ANSWER - Two drops in both ears two times daily - 2gtt : 2 drops - AU : both ears - BID: Twice a day NurseBernie What is CCXLIX equivalent to - CORRECT ANSWER - 249 Reducing a substance to fine particles using a mortar and pestle is know as - CORRECT ANSWER - Triturating - breaking down of compounds into their finer particles Automated dispensing machines - CORRECT ANSWER - Accu-DOse, Omicell, Pyxis and ScriptPro Digital pill counting machines - CORRECT ANSWER - Baker Cell and Kirby Lester How may days will the following prescription last ? - Famotidine: 20mg # 120 - Slg: Famitidine 40mg po BID - CORRECT ANSWER - - 30 days = 120 total # of tablets/ 4 # of tablets taken per day - Famotidine 40 mp BID = 4 tablets/ day How old must a person be to purchase an exempt narcotic or Schedule? - CORRECT ANSWER - 18 years old - The quantity of purchase, the date of purchase ad the residential address of the purchaser ( not PO Box) must be record T/F : a laminar flow hood is cleaned by using bleach and wate - CORRECT ANSWER - False - Need to be clean with water followed by 70% isopropyl alcohol T/F : A horizontal laminar flow hood can be used for compounding chemotherapy - CORRECT ANSWER - Hazardous products such as chemotherapy can only be compounded under a vertical flow hood or a barrier isolator with negative pressure T/F: compound sterile products are also known as extemporaneous compounding. - CORRECT ANSWER - False - Extemporanous compounding are non - commercially available and non sterile products that are prepared for specific patients in response to a physician's percription. T/F: A barrier isolator or a horizontal laminar flow hood can be used to compound IV antibiotics - CORRECT ANSWER - True To measure liquids in a graduated cylinder - CORRECT ANSWER - one must read at eye level the lower portion of the meniscus. - the meniscus is the concave shape that forms at the top of the graduated cylinder because od liquid's affinity to glass NurseBernie Which method would be the most accurate for determining the appropriate pediatric dose ? - CORRECT ANSWER - Drug- specific information from the manufacturer - PT should always refer to information from the manufacturer or packages insert for the most accurate drug-specific information Work area is designated by how many inches from the from edge and the sides of the laminar airflow hood? - CORRECT ANSWER - 6 inches from the edge and 6 inches from the sides to guard against contamination Fat Soluable Vitamin - CORRECT ANSWER - Vitamin D, E, A, K What is the most important thing to remember when preparing products using an ampoule? - CORRECT ANSWER - To use a filter needle to draw up the solution and to change the needle when injecting the solution into the JV bag or vice versa. - Itis also crucial to change the needle before transferring the solution into an IV bag because the needle used first could be contaminated with glass particle. - Using a5 micron filter to eliminate all glass particles How would 8:30 p.m. be expressed in military time? - CORRECT ANSWER - 2030 - 1:00 am = 0100 - After 12 noon = 1200 add 100 to each hr. - 1:00pm = 1300 which of the following procedures must be followed to prevent coring? - CORRECT ANSWER - Coring = a piece of the vial's rubber stopper broke off and entered the drug. - Inset the needle into the vial with the lumen side up - Insert the needle at a 45 - 60 angle The larger the needle gauge - CORRECT ANSWER - the smaller the diameter of the needle - SO 28-gauge needle is smaller than a 16- gauge needle What are the base components of a hyperalimentation admixture? - CORRECT ANSWER - Amino acid and dextrose or amino acids, dextrose and lipids combinations - Aminoc acide provide protein while dextrose provide energy A vertical laminar flow hood is reserved for the preparation of which of the following? - CORRECT ANSWER - Hazardous agents such as chemotherapy What is the generic name for Concerta? - CORRECT ANSWER - Methylphenidate Generic name for Amidate - CORRECT ANSWER - Etomidate Generic name for Diovan - CORRECT ANSWER - Valsartan Generic name for Lopressor - CORRECT ANSWER - Metoprolol NurseBernie Which is an anticonvulsant medication? - CORRECT ANSWER - Carbamazepine Which is an antineoplastic ? - CORRECT ANSWER - Etoposide Which is an sulfa antibiotic ? - CORRECT ANSWER - Sulfadiazine Which is an antidiabetic? - CORRECT ANSWER - Glipizide Which is an anti-neoplastic medication? - CORRECT ANSWER - Doxorubicin Which is an aminoglycoside? - CORRECT ANSWER - Amikacine Which is a tricyclic antidepressant? - CORRECT ANSWER - Doxepin Which is a macrolide antibiotic? - CORRECT ANSWER - Erythromycin How much codeine is found in Tylenol #3? - CORRECT ANSWER - 30 mg of codeine and 300 mg of acetaminophen Tylenol #1 - CORRECT ANSWER - Contains 8 mg of codeine and 325 mg of acetaminophen Tylenol # 2 - CORRECT ANSWER - Contains 15 mg of codeine and 300 mg of acetaminophen Tylenol # 4 - CORRECT ANSWER - Contains 60 mg of codeine and 300 mg of acetaminophen What is the generic name for Ternomin? - CORRECT ANSWER - Atenol What is the generic name for Coreg? - CORRECT ANSWER - Carvedilol What is the generic name for ProAir, Ventoline and Proventil? - CORRECT ANSWER - Albutero; What is the generic name for Lopressor? - CORRECT ANSWER - Metoprolol An FDA recall of a product that is not likely to result in any adverse health consequences is knnow as - CORRECT ANSWER - Recall II Why is a problem when one get tobramycin and gentamicin at the same time? - CORRECT ANSWER - Because there is a drug -drug interaction and both are aminoglycosides which may lead to serious adverse effects including liver toxicity NurseBernie - Percocet - Fentanyl - mesperidine - Hydromorphone - Methylphenidate - Adderall and secobarbital The Omnibus Reconciliation Act (OBRA) 1990 - CORRECT ANSWER - requires pharmacists to offer counseling on all new drup prescriptions The Food, Drug and Cosmetic Act of 1938 - CORRECT ANSWER - indicated that mis- branding and adulteration of drug is illegal. It also required manufacturers to provide package inserts and to follow FDA guidelines to present evidence of safety for new drugs before marketing. This law also gives the FDA authority to issue food standards and inspect factories/ Schedule | drugs - CORRECT ANSWER - such as LSD, PSP, Heroin and peyote - No medical use and highly abused. Schedule III drugs - CORRECT ANSWER - less abused than schedule II drugs - Include : Tylenol No.3. Vicodin, Marinol, testosterone and cough syrups containing hydrocodone. Schedule IV drugs - CORRECT ANSWER - comprised of mainly all the benzodiazepines - Include phentermine, pextazocine, phenobarbital and diethylpropion Schedule V drugs - CORRECT ANSWER - least abused of all the schedule drugs - Include antitussives with codeine and antidiarrheals with opioids. Which of the following organizations enforces the comprehensive drug abuse prevention and control act of 1970 ? - CORRECT ANSWER - DEA - Drug Enforcement Agency FDA- Food and Drug Administration - CORRECT ANSWER - which regulates prescription and over the counter drugs FBI - Federal Bureau of Investigation - CORRECT ANSWER - which is a governmental agency that investigates crimes SL - CORRECT ANSWER - the abbreviation for sub-lingual route SR - CORRECT ANSWER - the abbreviation for sustained release which refers to a drug formulation PR - CORRECT ANSWER - the abbreviation for rectum or rectal route NurseBernie SC - CORRECT ANSWER - the abbreviation for subcutaneous route A patient who is on captopril for her high blood pressure wants to purchase an OTC cough syrup. - CORRECT ANSWER - The patient may be experiencing a ACE cough as acommon side effects of ACE inhibitors and the pharmacist should be alerted Digibind is an antidote for which medications? - CORRECT ANSWER - Digoxin toxicity Vitamin K is an antidote for which medications? - CORRECT ANSWER - Coumadin The remainder of a partial filling fora schedule II drug must be available for the patient within how many hours? - CORRECT ANSWER - 72 hours . However, for long care facilities and terminally ill patients can be partially filled up to 60 days T/F : PT are not authorized to receive telephone orders. - CORRECT ANSWER - True. - Authorized healthcare professionals such as registered nurses , pharmacists and respiratory therapists may receive orders through telephone. The Combat Methamphetamine Epidemic Act of 2005 regulate.. - CORRECT ANSWER - Ephedrine Pseudoephedrine Phenylpropanolamine - stop the illegal production of crystal meth - A log book must be kept Once an investigational study is complete, what happens to the remaining drugs? - CORRECT ANSWER - they are returned to the sponsor with the record logs Which of the healthcare professionals cannot prescribe medications - CORRECT ANSWER - psychologist Side effect of anticholinergic agents - CORRECT ANSWER - Dry mouth, drownsiness, nausea, vomitting and restlessness or moodiness, lack of urination, blurred vision and confusion Side effect of cholinergic agents - CORRECT ANSWER - Hypo-tension, low heart rate, diarrhea, sweating or flushing, miosis and breathing difficulty Effective antidote to episodes of hypoglycemia - CORRECT ANSWER - Glucagon Side effect of alpha-adrenergic agonist agents - CORRECT ANSWER - Vasoconstriction, elevated blood pressure, rebound congestiona dn tremore Antiseptic - CORRECT ANSWER - can inhibit the growth of microorganisms and is usually a topical agent NurseBernie Vitamin B6 - CORRECT ANSWER - Pyridoxine Vitamin B 9 - CORRECT ANSWER - folic acid Vitamin B12 - CORRECT ANSWER - Cyanocobalamin HIPAA stand for - CORRECT ANSWER - Health Insurance Portability and Accountability Act a PT cannot perform - CORRECT ANSWER - DURs, contact prescribers regarding drug therapy modification and perform dispensing process validation. PT can perform - CORRECT ANSWER - transfer nonscheduled drug prescription between pharmacies with pharmacist approval How many times can Schedule III - V controlled substances be transferred between pharmacies? - CORRECT ANSWER - only one However, with electronically linked database can transfer infinite amount of times. A nuclear PT must have access to - CORRECT ANSWER - body and ring dose meters, protective clothing and a decontamination kit Anti-ineffective agents include - CORRECT ANSWER - antibiotic, antiviral and anti- fungal medications. - should be completed unless otherwise directed by the prescribe to avoid the development of resistance Suspension antibiotics - CORRECT ANSWER - should be refrigerated and shaken well. - Most have stability limit of 14 days unless otherwise indicated by the manufacturer Narcotics, muscle relaxants and anti-hypertensive agents may cause - CORRECT ANSWER - drowsiness and dizziness. these effects may be intensified by alcohol Which of the following can alter the effectiveness of birth control? - CORRECT ANSWER - Antibiotics can reduce the absorption and metabolism of birth control. Sulfonamides, fluoroquinolones and tetracyclinnes - CORRECT ANSWER - may cause phtosensitivity. - SHould be avoid sunlight Tetracycline agents - CORRECT ANSWER - should be taken wit empty stomach except for minocycline, doxycycline ad instances of long term use of tetracyclines Sulfoamides - CORRECT ANSWER - should be taken with plenty of water NurseBernie tetracycline and flouroquinolones - CORRECT ANSWER - should be taken within 1 hour of dairy products, antacids or iron preparations. Which fruit and fruit juices should be avoided while on calcium channel blockers and HMG-CoA enzyme inhibitors? - CORRECT ANSWER - Grape fruits herbal supplement chamomile - CORRECT ANSWER - - interfere with the efficacy of hormonal therapies cause addictive effects and side effects when used concurrently with benzodiazepines - Reduce effectiveness of birth control pills. - Interact with warfarin, which lead to increased effects resulting in overdose and hemorrhage Which of the following drugs require the distribution of a package insert to the patient? - CORRECT ANSWER - Accutance, birth control pills, metered dose inhalers and agents that contain estrogen or progesterone Which of the auxiliary labels should be affixed to containers of NSAIDs? - CORRECT ANSWER - Have to be taken with food and plenty of water to prevent GI upset Which of the auxiliary labels should be affixed to containers of cytotoxic agents ? - CORRECT ANSWER - Anti-neoplastic material and Handle properly vesicants - CORRECT ANSWER - can cause severe skin blistering in addition to eye ad mucosal pain and irritation. - Many chemotherapy Refrigerator temperature - CORRECT ANSWER - between 2 - 8 degree Celsius or 36- 47F Freezer temperature - CORRECT ANSWER - -20 to - 26 C or -4 to -14 F Who decides if a new drug on the market should be added to the hospital's drug formula? - CORRECT ANSWER - The Pharmacy and therapeutics ( P&T) committee - Composed of physicians, pharmacists and other health professionals. - Discussion of drug use, cost effectiveness, institutional compliance, distribution, administration and prescribing of drugs within the instituion Which is an anti-fungal medication? - CORRECT ANSWER - Most end with the suffix - COnazole Ex: Miconazole Anti-hypertensive drug class include - CORRECT ANSWER - ACE inhibitors, alpha blockers, alpha- beta blockers, angiotensin || reuptakke blockers, beta blockers, calcium channel blockers, diuretics , nervous inhibitors and vasodilators. NurseBernie Where should hazardous pharmaceutical waste be disposed? - CORRECT ANSWER - Must be disposed in approved hazardous waster containers to be transported by a hazardous waste transporter to hazardous waste disposal facilities The Environmental Protection Agency ( EPA) - CORRECT ANSWER - governs the management of pharmaceutical hazardous waste The Joint Commission ( TJC) - CORRECT ANSWER - accredits healthcare organization How are pharmaceutical labels disposed in a long term care facility ? - CORRECT ANSWER - Confidential data shredding bucket Where should be the gowns and gloves used in the chemotherapy compounding be disposed? - CORRECT ANSWER - Yellow chemo waste bag - Include gowns, gloves, goggles, tubing and wipes Red biohazard bags - CORRECT ANSWER - used for disposal of blood contaminated material or other potentially infectious material such as reserved for needles, vials syringes Where should partially used chemotherapy vials be disposed? - CORRECT ANSWER - Yellow chemotherapy waste sharps containers - Include all chemotherapy vials, syringes, needles and empty IV bags What is the name of the government agency that administer Medicare and Medicaid ? - CORRECT ANSWER - CMS- Center for Medicare and Medicaid services is a U.S. federal government agency that administers all laws and policies related to Medicare and Medicaid Medicare part A - CORRECT ANSWER - deals with impatient services such as hospitals stays, care in skilled nursing facilities, hospice care and home health care Medicare part B - CORRECT ANSWER - covers outpatient visits Medicare part C - CORRECT ANSWER - combines coverage for part A and part B Medicare part D - CORRECT ANSWER - voluntary insurance benefit for outpatient prescription coverage enacted as part of the Drug Improvement and Modernization Act ( MMS) of 2003 The set order points system - CORRECT ANSWER - based on minimum and maximum ordering points. This required visual inspection of stocks to determine the reordering quantity for each item available in the pharmacy. If the information is processed through the computer, it will make it easier to determine the needed inventory levels. NurseBernie The perpetual inventory system - CORRECT ANSWER - utilizes a computer system to scan all new items received by the pharmacy. All items sold or dispensed are automatically deducted from the inventory. This system can also keep track of minimum and maximum levels if they are inputted into the computer. However, this required periodic verification of stock against computer data The point of sale system ( POS) - CORRECT ANSWER - utilize a computer to keep a perpetual inventory. All items sold are scanned and automatically deducted from the inventory. This makes it easy to reorder and keep track of medication counts.. According to the DEA, how often must a full inventory of control substances take place? - CORRECT ANSWER - Every 2 years Pharmacies prefer purchasing most of their stock from wholesales or distributors because .. - CORRECT ANSWER - - It is difficult to deal with all the different manufacturers. -Wholesalers stock most medications at competitive prices - Wholesalers make daily deliveries and provide systems for ordering medications. Where should Schedule || narcotics be stored ? - CORRECT ANSWER - -Separately in a secure place, preferably in a locked compartment because they are highly abused. They should not be dispersed on the shelf with other prescription medication. How soon should the supplier be paid for stock purchases? - CORRECT ANSWER - Within 30 days from the date of delivery. otherwise, service charges may be added to unpaid balance => higher costs New stock items should be inspected for which of the following? - CORRECT ANSWER - All newly received stock items should be inspected for item names and quantities, expiration dates and any damage during shipping. Damages and expired or soon to be expires stock received can be returned to the wholesaler for credit. Chemotherapy medications and investigation drugs should be dispersed on... - CORRECT ANSWER - shelf with other prescription medication Which of the items can be returned to reverse distributors or the manufacturer for credit? - CORRECT ANSWER - Unused or expired medications. - Partially used or reconstituted medications are considered waste and cannot be returned for credit. What is the proper way of handling an unopened prescription vial that was returned by the patient? - CORRECT ANSWER - -the medication should be credited and destroyed within 72 hours -a destruction record should be kept on file NurseBernie The centers for Medicare and Medicaid Services ( CMS) - CORRECT ANSWER - U.S. federal government agency that administers all laws and policies related to Medicare and Medicaid Want book - CORRECT ANSWER - am old and widely used method of inventory control used in management of set order points - Now replace by the wireless handheld device which can look up items by barcode scan and allow for the information to be directly transferred to the main computer ordering. Total control of quality of drugs is the responsibility .. - CORRECT ANSWER - the entire pharmacy department which include pharmacy direction, the pharmacists, and the PT. Quality control of medications encompasses ..- CORRECT ANSWER - - Formulation, compounding and dispensing -Packaging, purchasing and storage -Distribution of medication to the patient Which of the following negotiates medication prices for institutions but does not make the actual purchases? - CORRECT ANSWER - The group purchasing organization - does not make the actual purchase. - assist in promoting quality healthcare in effectively managing expenses. Which of the following drugs can be crystallize at very low temperature? - CORRECT ANSWER - - Mannitol should be stored at room temperature. If it crystallizes, it should be placed in an autoclave for at least 20 minutes until | crystals have dissolved How long is nitroglycerin sub-lingual stable after opening the container? - CORRECT ANSWER - Only for 6 months Which of the following represents drug diversion cases? - CORRECT ANSWER - - The use of addictive drugs for non-therapeutic purposes - The illegal distribution of drugs - Prescription forgery such as faking prescription to obtain medications illegally. What is the beyond- use date of a multi-dose vial such as insulin injection after opening? - CORRECT ANSWER - 28 days Sterility of compounded sterile products (CSPs) - CORRECT ANSWER - -Free of microorganisms Which can result from the lack of stability of a compounded sterile products? - CORRECT ANSWER - Chemical and physical characteristic changes such as color change, precipitate formation and chemical degradation NurseBernie Where should Xalatan eye drops be stored? - CORRECT ANSWER - Xalatan eye drops or latamoprost should be refrigerated per the manufacturer's recommendation. At room temperature, the medication loses its stability Which medications should be protected from lights? - CORRECT ANSWER - Nitroglycerin, sulfadiazine and methylprednisolone Just in time ordering - CORRECT ANSWER - -Supply item close too the time of use, reduce large inventories and decrease cost and space requirement The preferred provide organization (PPO) - CORRECT ANSWER - - requires higher co-payments but allows patients a wide range of access to out- of- network physicians. The health maintenance organization ( HMO) - CORRECT ANSWER - - Requires lower co-payments but gives patients restricted access to out of network physicians. How long are drug patents effective? - CORRECT ANSWER - 20 years from the date of patent application filing Clinical trial phase |- CORRECT ANSWER - Involves 20 to 100 patient volunteers and is intended to determine safety and dosage of an experimental drug Clinical trial phase Il - CORRECT ANSWER - Involves 100 to 500 patient volunteers and is intended to evaluate effectiveness and look for side effects of an experimental drug Clinical trial phase III - CORRECT ANSWER - Involves 1000 to 5000 patients volunteers to confirm effectiveness and monitor adverse effects associated with long- term use of an experimental drug Clinical trial phase IV - CORRECT ANSWER - involves post-marketing studies required by the FDA to determine long-term safety of an experimental drug How long should records for controlled substances be stored? - CORRECT ANSWER - For a minimum of 2 years to provide accountability of all controlled substances received and dispensed in case of errors. Another name for a decentralized pharmacy unit? - CORRECT ANSWER - Satellite Unit Accounts for insurance claim rejection - CORRECT ANSWER -- Invalid patient information - Patient loss of insurance coverage - Maximum benefit has been reached - Early refill request - Selected drug is covered NurseBernie Which is used to filter out glass particles when preparing sterile products from ampules? - CORRECT ANSWER - A 5 micron filter According to USP 797, how often should a compounder performing low- to -medium- risk preparations undergo validation testing? - CORRECT ANSWER - Once every year According to USP 797, how often should a compounder performing high- risk preparation undergo validation testing? - CORRECT ANSWER - Every 6 months Which is the most effective way to prevent contamination and the spread of infection within a hospital? - CORRECT ANSWER - Hand washing How long should a compounding PT scrub the hands and up to the elbow with warm water and antimicrobial soap? - CORRECT ANSWER - At least 30 to 90 seconds How often should all work surfaces and flooring of a clean room be sanitized? - CORRECT ANSWER - Every day to eliminate contaminants Ata minimum, how often should PT sanitize the walls and ceilings of a clean room? - CORRECT ANSWER - Monthly How often should a PT sanitize the walls and ceilings of an anteroom? - CORRECT ANSWER - Weekly - The anteroom is the area outside the clean room where stock is stored and garbing takes place. How long should the laminar air flow hood be turned on before use? - CORRECT ANSWER - At least 30 minutes and it should be disinfected Which of the following is the proper garbing order? - CORRECT ANSWER - Head cover, face mask, beard cover, shoe covers, hand wash, gown and gloves How often should pharmacy balances be evaluated? - CORRECT ANSWER - Once every year What is the purpose of a breakdown room in a nuclear pharmacy? - CORRECT ANSWER .- is a restricted area where radio pharmaceutical returns or waste are accepted and broken down into different waste barrels The quality control area of a nuclear pharmacy - CORRECT ANSWER - the location where quality assurance testing may be performed the compounding area of a nuclear pharmacy - CORRECT ANSWER - Is the dispensing area NurseBernie The packaging area of a nuclear pharmacy - CORRECT ANSWER - where radio pharmaceuticals are packaged for delivery The U.S department of Transportation - CORRECT ANSWER - regulates the transport of hazardous materials - ls concerned with loading, movement and transportation of wastes by all models of transportation - regulates specific types of waste containers, labels, marketing and vehicle placards The Federal Hazardous Materials Transportation Law - CORRECT ANSWER - Regulate transportation of hazmat which requires