RENAL PATH MCQS
1. This manifestation of renal failure is usually due to uraemia:
A: encephalopathy โ
B: hyperphosphataemia
C: hypertension
D: oedema
2. What is most important in the pathogenesis of post-infectious glomerulonephritis?
A: activation of alternative complement pathway
B: anti-basement membrane antibodies
C: direct podocyte injury
D: immune complex formation โ
3. A previously well child presents with generalised oedema. You diagnose nephrotic
syndrome. The most likely underlying disease is:
A: dense deposit disease
B: focal & segmental glomerulosclerosis
C: membranous nephropathy
D: minimal change disease โ
4. A man with poorly-controlled hypertension develops renal failure. What pathological lesion
is causing this?
A: corticomedullary scarring
B: fibromuscular dysplasia
C: hyperplastic arteriolitis โ
D: papillary necrosis
5. A patient is resuscitated from cardiac arrest & his creatinine begins to rise. Which part of
his nephron is most vulnerable to damage by ischaemia?
A: ascending limb of the loop of Henle โ
B: distal convoluted tubule
C: glomerulus
D: proximal convoluted tubule
6. An elderly man develops acute pyelonephritis. The most common underlying cause is
A: haematogenous spread of infection
B: malformation of the vesicoureteric junction
C: stasis of urine in the bladder โ
D: ureteric obstruction
