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RESPIRATORY SYSTEM DISORDERS
LEARNING OUTCOME
- Anatomy and physiology review
- Special respiratory investigations
- Alterations of the respiratory system in disease
- Classification of respiratory diseases
- Management of respiratory diseases
Functions of the respiratory system
- Oxygen transport
- Carbon dioxide transport
- Respiration
- ventilation
Diagnostic evaluation
- The respiratory system is vital part of human body.
- Diagnostic tests in respiratory system are mainly divided
into :
❑Invasive test ❑Non invasive test
- Diagnostic tests are performed to find problems as early
as possible
Non invasive diagnostic procedures
- Bronchoscopy
- Radiological imaging :
- X-ray
- CT scan
- MRI
- CT angiography
UPPER RESPIRATORY TRACT INFECTIONS
Definition
- Inflammation of the nasal mucosa.
- Rhinitis is a group of disorders characterized by inflammation and irritation of the mucous membranes of the nose.
Classification
A. Acute rhinitis a. Non-allergic:
1. Infective:
- Viral: Common cold (coryza or flu), rhinitis associated with influenza or other viral infections.
- Bacterial: Usually occurs as a secondary infection following unresolved viral rhinitis. 2. Non-infective:
- Vasomotor rhinitis.
- Rhinitis due to chemical irritation.
B. Chronic rhinitis: a. Non-allergic:
1. Non-specific:
- Chronic catarrhal rhinitis.
- Chronic hypertrophic rhinitis.
- Chronic atrophic rhinitis.
- **Rhinitis medicamentosa (drug-induced rhinitis).
- Specific:**
- Scleroma.
- Rare types: Syphilis, tuberculosis, lupus and, leprosy. b. Allergic: Perennial allergic rhinitis.
CAUSES
1. Rhinovirus.
- Reaction of the body’s immune system to an environmental trigger. The most common environmental triggers include dust, molds, pollens, grasses, trees, and animals. Both seasonal allergies and year-round allergies can cause allergic rhinitis.
Cont.,
6. medications (eg, penicillin, sulfa medications, aspirin
- The most common cause of nonallergic rhinitis is the
common cold.
- Drug-induced rhinitis may occur with
antihypertensive agents, such as angiotensin-
converting enzyme (ACE) inhibitors and beta-
blockers; “statins,” antidepressants; aspirin,
antianxiety medications.
Clinical features
1. Stage of invasion (few hours): Sneezing, burning sensation in the nasopharynx, nasal obstruction, and headache, Pruritis of nose 2. Stage of secretion (few days):
- Symptoms lasting beyond 7 days, or worsening instead of improving suggest that secondary bacterial infection is being established.
- Low grade fever, malaise, arthralgia, nasal obstruction, and profuse watery rhinorrhea. 3. Stage of resolution: Resolution within 5 - 7 days is the natural course of an uncomplicated disease.