Download Safety Data Sheet for Sodium Acetate and more Exams Molecular biology in PDF only on Docsity!
SECTION 1: Identification of the substance/mixture and of the company/
undertaking
1.1 Product identifier Identification of the substance Sodium acetate ≥99 %, p.a., ACS, anhydrous, for molecular biology Article number 6773 Registration number (REACH) 01-2119485123-42-xxxx EC number 204-823- CAS number 127-09- 1.2 Relevant identified uses of the substance or mixture and uses advised against Relevant identified uses: Laboratory chemical Laboratory and analytical use Uses advised against: (^) Do not use for products which come into contact with foodstuffs. Do not use for private purposes (household). 1.3 Details of the supplier of the safety data sheet Carl Roth GmbH + Co KG Schoemperlenstr. 3- D-76185 Karlsruhe Germany Telephone: +49 (0) 721 - 56 06 0 Telefax: +49 (0) 721 - 56 06 149 e-mail: [email protected] Website: www.carlroth.de Competent person responsible for the safety data sheet:
:Department Health, Safety and Environment e-mail (competent person): [email protected] 1.4 Emergency telephone number Name Street (^) code/cityPostal Telephone Website National Poisons InformationCentre Beaumont Hospital
Beaumont Road Dublin 9 01 809 2166 (^) www.poisons.ie/https://
Sheet format according to Regulation (EC) No. 1907/
(REACH)
Sodium acetate ≥99 %, p.a., ACS, anhydrous, for molecular biology
article number: 6773 Version: 4.1 en Replaces version of: 2021-11- Version: (4)
date of compilation: 2015-06- Revision: 2022-01-
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 (CLP) This substance does not meet the criteria for classification in accordance with Regulation No 1272/ 2008/EC. 2.2 Label elements Labelling according to Regulation (EC) No 1272/2008 (CLP) not required 2.3 Other hazards Results of PBT and vPvB assessment According to the results of its assessment, this substance is not a PBT or a vPvB.
SECTION 3: Composition/information on ingredients
3.1 Substances Name of substance Sodium acetate Molecular formula C₂H₃O₂Na Molar mass 82,03 g/mol REACH Reg. No 01-2119485123-42-xxxx CAS No 127-09- EC No 204-823-
SECTION 4: First aid measures
4.1 Description of first aid measures
General notes Take off contaminated clothing. Following inhalation Provide fresh air. In all cases of doubt, or when symptoms persist, seek medical advice. Following skin contact Rinse skin with water/shower. In all cases of doubt, or when symptoms persist, seek medical advice. Following eye contact Rinse cautiously with water for several minutes. In all cases of doubt, or when symptoms persist, seek medical advice. Following ingestion Rinse mouth. Call a doctor if you feel unwell.
Sheet format according to Regulation (EC) No. 1907/
(REACH)
Sodium acetate ≥99 %, p.a., ACS, anhydrous, for molecular biology
article number: 6773
6.4 Reference to other sections Hazardous combustion products: see section 5. Personal protective equipment: see section 8. Incom- patible materials: see section 10. Disposal considerations: see section 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling When not in use, keep containers tightly closed. Advice on general occupational hygiene Keep away from food, drink and animal feedingstuffs. 7.2 Conditions for safe storage, including any incompatibilities Store in a dry place. Keep container tightly closed. Hygroscopic solid. Incompatible substances or mixtures Observe hints for combined storage. Protect against external exposure, such as humidity Consideration of other advice: Specific designs for storage rooms or vessels Recommended storage temperature: 15 – 25 °C 7.3 Specific end use(s) No information available.
SECTION 8: Exposure controls/personal protection
8.1 Control parameters National limit values Occupational exposure limit values (Workplace Exposure Limits) This information is not available. Human health values Relevant DNELs and other threshold levels Endpoint Thresholdlevel route of exposureProtection goal, Used in Exposure time DNEL 1.058 mg/m³ human, inhalatory worker (industry) chronic - systemic effects DNEL 6.347 mg/m³ human, inhalatory worker (industry) acute - systemic effects DNEL 12 mg/kg bw/day human, dermal worker (industry) chronic - systemic effects DNEL 72 mg/kg bw/day human, dermal worker (industry) acute - systemic effects
Sheet format according to Regulation (EC) No. 1907/
(REACH)
Sodium acetate ≥99 %, p.a., ACS, anhydrous, for molecular biology
article number: 6773
Environmental values Relevant PNECs and other threshold levels
point^ End- Thresholdlevel Organism^ Environmental com-partment Exposure time PNEC 0,1 mg/l aquatic organisms freshwater short-term (single instance) PNEC 0,01 mg/l aquatic organisms marine water short-term (single instance) PNEC 0,72 g/l aquatic organisms sewage treatment plant(STP) short-term (single instance) PNEC 0 mg/kg aquatic organisms freshwater sediment short-term (single instance) PNEC 0 mg/kg aquatic organisms marine sediment short-term (single instance) PNEC 0 mg/kg terrestrial organisms soil short-term (single instance)
8.2 Exposure controls Individual protection measures (personal protective equipment) Eye/face protection
Use safety goggle with side protection. Skin protection
- hand protection Wear suitable gloves. Chemical protection gloves are suitable, which are tested according to EN 374. - type of material NBR (Nitrile rubber) - material thickness
0,11 mm
- breakthrough times of the glove material
480 minutes (permeation: level 6) - other protection measures Take recovery periods for skin regeneration. Preventive skin protection (barrier creams/ointments) is recommended. Respiratory protection
Sheet format according to Regulation (EC) No. 1907/
(REACH)
Sodium acetate ≥99 %, p.a., ACS, anhydrous, for molecular biology
article number: 6773
Other safety parameters Oxidising properties none 9.2 Other information Information with regard to physical hazard classes:
hazard classes acc. to GHS (physical hazards): not relevant Other safety characteristics: There is no additional information.
SECTION 10: Stability and reactivity
10.1 Reactivity The product in the delivered form is not dust explosion capable; the enrichment of fine dust however leads to the danger of dust explosion. 10.2 Chemical stability Hygroscopic solid. 10.3 Possibility of hazardous reactions
Violent reaction with: Oxidisers, Nitrate, Permanganates, for example potassium permanganate 10.4 Conditions to avoid Keep away from heat. Decompostion takes place from temperatures above: 324 °C. Protect from moisture. 10.5 Incompatible materials There is no additional information. 10.6 Hazardous decomposition products Hazardous combustion products: see section 5.
SECTION 11: Toxicological information
11.1 Information on hazard classes as defined in Regulation (EC) No 1272/ Classification according to GHS (1272/2008/EC, CLP) This substance does not meet the criteria for classification in accordance with Regulation No 1272/ 2008/EC. Acute toxicity Shall not be classified as acutely toxic. Acute toxicity Exposure route Endpoint Value Species Method Source oral LD50 2.700 mg/kg rat ECHA inhalation: dust/mist LC50 >5,6 mg/l/4h rat ECHA dermal LD50 >20.000 mg/kg rabbit ECHA Skin corrosion/irritation Shall not be classified as corrosive/irritant to skin.
Sheet format according to Regulation (EC) No. 1907/
(REACH)
Sodium acetate ≥99 %, p.a., ACS, anhydrous, for molecular biology
article number: 6773
Serious eye damage/eye irritation Shall not be classified as seriously damaging to the eye or eye irritant. Respiratory or skin sensitisation Shall not be classified as a respiratory or skin sensitiser. Germ cell mutagenicity Shall not be classified as germ cell mutagenic. Carcinogenicity Shall not be classified as carcinogenic. Reproductive toxicity Shall not be classified as a reproductive toxicant. Specific target organ toxicity - single exposure Shall not be classified as a specific target organ toxicant (single exposure). Specific target organ toxicity - repeated exposure Shall not be classified as a specific target organ toxicant (repeated exposure). Aspiration hazard Shall not be classified as presenting an aspiration hazard. Symptoms related to the physical, chemical and toxicological characteristics
- If swallowed Data are not available. - If in eyes Data are not available. - If inhaled Data are not available. - If on skin Frequently or prolonged contact with skin may cause dermal irritation - Other information none 11.2 Endocrine disrupting properties Not listed. 11.3 Information on other hazards There is no additional information.
Sheet format according to Regulation (EC) No. 1907/
(REACH)
Sodium acetate ≥99 %, p.a., ACS, anhydrous, for molecular biology
article number: 6773
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Consult the appropriate local waste disposal expert about waste disposal. Sewage disposal-relevant information Do not empty into drains. 13.2 Relevant provisions relating to waste The allocation of waste identity numbers/waste descriptions must be carried out according to the EEC, specific to the industry and process. Waste catalogue ordinance (Germany). 13.3 Remarks Waste shall be separated into the categories that can be handled separately by the local or national waste management facilities. Please consider the relevant national or regional provisions.
SECTION 14: Transport information
14.1 UN number or ID number not subject to transport regulations 14.2 UN proper shipping name not assigned 14.3 Transport hazard class(es) none 14.4 Packing group not assigned 14.5 Environmental hazards non-environmentally hazardous acc. to the dan- gerous goods regulations 14.6 Special precautions for user There is no additional information. 14.7 Maritime transport in bulk according to IMO instruments The cargo is not intended to be carried in bulk.
14.8 Information for each of the UN Model Regulations Transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN) - Additional information Not subject to ADR, RID and ADN. International Maritime Dangerous Goods Code (IMDG) - Additional information Not subject to IMDG. International Civil Aviation Organization (ICAO-IATA/DGR) - Additional information Not subject to ICAO-IATA.
Sheet format according to Regulation (EC) No. 1907/
(REACH)
Sodium acetate ≥99 %, p.a., ACS, anhydrous, for molecular biology
article number: 6773
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture Relevant provisions of the European Union (EU) Restrictions according to REACH, Annex XVII not listed List of substances subject to authorisation (REACH, Annex XIV)/SVHC - candidate list Not listed. Seveso Directive 2012/18/EU (Seveso III) No Dangerous substance/hazard categories Qualifying quantity (tonnes) for the ap-plication of lower and upper-tier re- quirements
Notes
not assigned Deco-Paint Directive VOC content 0 % , 0 g/l Industrial Emissions Directive (IED) VOC content 0 % VOC content 0 g/l Directive on the restriction of the use of certain hazardous substances in electrical and electronic equipment (RoHS) not listed Regulation concerning the establishment of a European Pollutant Release and Transfer Register (PRTR) not listed Water Framework Directive (WFD) List of pollutants (WFD) Name of substance Name acc. to inventory CAS No Listed in Remarks Sodium acetate Metals and their compounds A) Legend A) Indicative list of the main pollutants Regulation on the marketing and use of explosives precursors not listed Regulation on drug precursors not listed Regulation on substances that deplete the ozone layer (ODS) not listed
Sheet format according to Regulation (EC) No. 1907/
(REACH)
Sodium acetate ≥99 %, p.a., ACS, anhydrous, for molecular biology
article number: 6773
SECTION 16: Other information
Indication of changes (revised safety data sheet) Alignment to regulation: Regulation (EC) No. 1907/2006 (REACH), amended by 2020/878/EU Restructuring: section 9, section 14 Section Former entry (text/value) Actual entry (text/value) Safety-relev- ant 2.2 Signal word:not required yes 2.3 (^) There is no additional information.Other hazards: Other hazards yes 2.3 (^) According to the results of its assessment, thisResults of PBT and vPvB assessment: substance is not a PBT or a vPvB.
yes
Abbreviations and acronyms Abbr. Descriptions of used abbreviations ADN (^) tion intérieures (European Agreement concerning the International Carriage of Dangerous Goods by In-Accord européen relatif au transport international des marchandises dangereuses par voies de naviga- land Waterways) ADR Accord relatif au transport international des marchandises dangereuses par route (Agreement concern-ing the International Carriage of Dangerous Goods by Road) CAS Chemical Abstracts Service (service that maintains the most comprehensive list of chemical substances) CLP Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures DGR Dangerous Goods Regulations (see IATA/DGR) DNEL Derived No-Effect Level EC50 Effective Concentration 50 %. The EC50 corresponds to the concentration of a tested substance causing50 % changes in response (e.g. on growth) during a specified time interval EC No The EC Inventory (EINECS, ELINCS and the NLP-list) is the source for the seven-digit EC number, an identi-fier of substances commercially available within the EU (European Union) EINECS European Inventory of Existing Commercial Chemical Substances ELINCS European List of Notified Chemical Substances ErC50 ≡ EC50: in this method, that concentration of test substance which results in a 50 % reduction in eithergrowth (EbC50) or growth rate (ErC50) relative to the control GHS "Globally Harmonized System of Classification and Labelling of Chemicals" developed by the United Na-tions IATA International Air Transport Association IATA/DGR Dangerous Goods Regulations (DGR) for the air transport (IATA) ICAO International Civil Aviation Organization IMDG International Maritime Dangerous Goods Code LC50 Lethal Concentration 50%: the LC50 corresponds to the concentration of a tested substance causing 50 %lethality during a specified time interval
Sheet format according to Regulation (EC) No. 1907/
(REACH)
Sodium acetate ≥99 %, p.a., ACS, anhydrous, for molecular biology
article number: 6773
Abbr. Descriptions of used abbreviations LD50 Lethal Dose 50 %: the LD50 corresponds to the dose of a tested substance causing 50 % lethality during aspecified time interval NLP No-Longer Polymer PBT Persistent, Bioaccumulative and Toxic PNEC Predicted No-Effect Concentration REACH Registration, Evaluation, Authorisation and Restriction of Chemicals RID Règlement concernant le transport International ferroviaire des marchandises Dangereuses (Regula-tions concerning the International carriage of Dangerous goods by Rail) SVHC Substance of Very High Concern VOC Volatile Organic Compounds vPvB Very Persistent and very Bioaccumulative Key literature references and sources for data Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures. Regulation (EC) No. 1907/2006 (REACH), amended by 2020/878/EU. Transport of dangerous goods by road, rail and inland waterway (ADR/RID/ADN). International Mari- time Dangerous Goods Code (IMDG). Dangerous Goods Regulations (DGR) for the air transport (IATA). Disclaimer This information is based upon the present state of our knowledge. This SDS has been compiled and is solely intended for this product.
Sheet format according to Regulation (EC) No. 1907/
(REACH)
Sodium acetate ≥99 %, p.a., ACS, anhydrous, for molecular biology
article number: 6773
