Download SBB TESTS COMPILATION BUNDLE EXAM SCRIPT 2026 COMPREHENSIVE QUESTIONS WITH SOLUTIONS GRADE and more Exams Hematology in PDF only on Docsity!
SBB TESTS COMPILATION BUNDLE EXAM
SCRIPT 2026 COMPREHENSIVE QUESTIONS
WITH SOLUTIONS GRADED A+
⩥ What antibody is enhanced by enzyme treatment of red cells? Answer: Rh, Lewis, and Kidd antibodies ⩥ A secondary immune response is generally associated with what antibody? Answer: IgG ⩥ All of the following would be situations where you would typically find an increase in eosinophils, except? Answer: Viral infections ⩥ what is the correct sequence of the immunologic Epstein-Barr virus response in infectious mononucleosis? Answer: VCA, EBNA, VCA/IgM, EA ⩥ what organism causes White Piedra, which infects hairs on the face, scalp, and body areas? Answer: Trichosporon beigelii ⩥ The purpose of C3a and C5a, the split-products of the complement cascade, is to? Answer: Cause increased vascular permeability, contraction of smooth muscle, and release of histamine from basophils.
⩥ A patient presents to his doctor with respiratory issues. He has a history of heavy smoking for over 20 yrs, so the physician orders a BAL cell count w/differential. What cell would most closely correlate with the medical history? Answer: Macrophages with purple/black inclusions ⩥ For best results, if not tested immediately, a semen sample should remain at what temperature after collection? Answer: 37 C° ⩥ What should be done first if a donor unit of RBC's is found to be incompatible at the antiglobulin phase but compatible T immediate spin with several different recipients? Answer: Perform a direct antiglobulin test (DAT) on the donor unit ⩥ Serous fluid effusions may result from all of the following except? Answer: Dehydration ⩥ The following factors are measured by either PT or aPTT except? Answer: Factor XIII ⩥ Str. Pneumoniae can best be differentiated from the viridans group of streptococci by which characteristic? Answer: Bile solubility ⩥ What type of toxicology is primarily concerned with medical and legal consequences of exposure to chemicals and drugs? Answer: Forensic toxicology
⩥ What is not true concerning C. diff? Answer: It is an aerobic organism ⩥ What antibodies usually show enhanced agglutination with the use of proteolytic enzymes? Answer: Anti-Jka, - Jkb, - C, and - E ⩥ What is the antigen marker best associated with stem cells? Answer: CD ⩥ What organism is likely to be contracted following consumption of unpasteurized milk? Answer: Listeria monocytogenes ⩥ What kind of immunoglobulins are predominantly found in Rh immune globulin? Answer: IgG anti-D ⩥ Increased concentration of alpha-fetoprotein in adults are kost characteristically associated with? Answer: Hepatocellular carcinoma ⩥ How many 1mm x 1mm squares is the Neubauer hemacytometer counting grid composed of? Answer: Nine per side ⩥ What does M:E ratio in a bone marrow evaluation represent? Answer: Myeloid cells to erythroid cells
⩥ What blood group antigen-antibody reaction is enhanced by using enzymes? Answer: Jka ⩥ An aqueous 3.00 M KOH solution is prepared with a total volume of 0.650 L. The molecular weight of KOH is 56.1056 g/mol. What mass of KOH (in grams) is needed for the solution? Answer: 109.4 g ⩥ What is the International Normalized Ratio (INR) calculation used for? Answer: Standardize PT results between different reagent sensitivities ⩥ Which of the following is considered a cause of hypomagnesemia (low magnesium in the blood) Answer: Pancreatitis ⩥ What transfusion reactions is most often associated with transfused patients lacking IgA? Answer: Anaphylaxis ⩥ A 22-year-old construction worker incurred 3rd degree burns to the chest and arms when a boiler he was installing blew up. On the 5th hospital day, the weeping wounds became infected, exuding what was described as green pus. what is the most likely bacterial cause of the infection? Answer: Pseudomonas aeruginosa ⩥ What cells are considered abnormal and clinically significant on a CSF differential? Answer: Myeloblast
⩥ What is true regarding amylase and lipase in pancreatitis? Answer: Amylase and lipase are as predictive in chronic as in acute pancreatitis ⩥ Patients with antibody to what antigen are immune to hepatitis B? Answer: Surface antigen ⩥ What characteristic is usually associated with IgM antibodies directed against red cells? Answer: React best at room temperature ⩥ What type of white blood cell is seen lost frequently in urine sediment with infections of the urinary system? Answer: Neutrophil ⩥ Vitamin D is controlled by which hormone in a negative feedback loop? Answer: PTH ⩥ Hepatitis B serology results: HBsAg: Positive HBeAg: positive Anti-HBc IgM: Positive Anti-HBs: Negative what is the immune status of the patient? Answer: Acute infection ⩥ Calcium and phosphorus levels for a 4 yr old patient were:
Ca- 14 mg/dl Phosphorus- 1 mg=/dl what do these results indicate? Answer: Hyperparathyroidism ⩥ Bordet-Gengou potato infusion agar is the medium of choice for the recovery of what organism? Answer: Bordatella pertussis ⩥ The property most responsible for the migration of proteins in an electrical field is? Answer: Net surface charge ⩥ The granules that basophils contain are composed of? Answer: Histamine ⩥ What would be considered a common characteristic of anti-Jka and anti-Jkb? Answer: The antibodies show dosage of Kidd antigens on red cells ⩥ What genotype is know to be resistant to P. vivax (malaria) merozoites? Answer: Fy(a-, b-) ⩥ What cardiovascular risk marker is a more sensitive version of a test that is used to assess inflammation? Answer: hs-CRP
⩥ How long are healthy neutrophils expected to stay in the peripheral blood of an adult? Answer: 7-8 hours ⩥ What results would be indicative of stage 3 iron deficiency (iron deficiency anemia)? Answer: Decreased ferritin, increased sTfR, increased TIBC ⩥ A stool from a 2 yr old girl grew clear colonies on MacConkey agar, red colonies on XLD (w/out black centers), and green colonies on HE (w/out black centers). It is ornithine positive and indole negative. It should agglutinate antisera of which serogroup of the somatic O antigen? Answer: D ⩥ In the in vitro coagulation scheme, factor V is primarily involved in the? Answer: Common pathway ⩥ Precision is a measure of: Answer: random variability ⩥ A tech is working on a urine culture and notices that the agar plates are not streaked properly. The tech decides that that culture must be reset. Where should the tech document this finding and the actions taken? Answer: Place all notes in the culture work card
⩥ Lewis Blood Group System is a human blood group unlike most others. The antigen is produced and secreted by exocrine glands, eventually adsorbing to the surface of red blood cells. Its expression is based on the genetic expression of the Lewis and Secretor genes. Based on the following genotype (Le) (sese), what would you predict the Lewis antigen phenotypic expression to be? Answer: Le(a+ b-) ⩥ All of the following organisms can exhibit beta hemolysis, EXCEPT: Answer: Shigella sp. ⩥ When transporting donated platelet units, what is the maximum amount of time that agitation of platelets can be stopped for? Answer: 1 hour ⩥ The type of hypersensitivity reaction associated with macrophage activation, cytokine-mediated inflammation is: Answer: Type IV Cell mediated hypersensitivity (T-cell dependent) ⩥ The class of protozoa with no apparent organelles for locomotion is known as: Answer: Sporozoa ⩥ Sudan III will confirm the presence of: Answer: Fat
Which of the following diagnoses can be EXCLUDED based on laboratory data and current symptoms and history? Answer: Acute hepatitis A ⩥ All outpatient tests are reimbursed according to a group of code numbers which are called: Answer: Current Procedural Terminology (CPT) codes ⩥ Which laboratory assay is a highly specific indicator and the most sensitive assay for a diagnosis of rheumatoid arthritis? Answer: Cyclic citrullinated peptide ⩥ Which anaerobic bacteria incidence is increasing in CSF shunt infections? Answer: Cutibacterium (Propionibacterium) acnes ⩥ During which stage of a syphilis infection will a patient develop the painless chancre? Answer: First stage ⩥ Which age group has been most affected by the H1N1 virus? Answer: Children ⩥ Antibodies within which of the following blood group systems are known to result in severe hemolytic transfusion reactions, but are not always detected during pre-transfusion testing in the blood bank? Answer: Kidd
⩥ The proper storage requirements for granulocyte concentrates is: Answer: 20 - 24 degrees Celsius, 24 hours ⩥ The decreased serum iron levels seen in anemia of chronic disease (also referred to as anemia of chronic infection or inflammation) is caused by which of the following? Answer: Decreased iron released from macrophages ⩥ Which one of the following parasites migrates through the circulation (blood) before maturing in the portal venous system? Answer: Schistosoma mansoni ⩥ For transfusion services in the United States, which of the following incidents must be reported to the Food and Drug Administration (FDA) because of a biological product deviation? Answer: Incident C: The wrong specimen was used to crossmatch a unit and the unit was issued. ⩥ Which analyte should be increased in the presence of muscular dystrophy? Answer: Aldolase ⩥ Which two of the following biomarkers are not specific to cardiac muscle and may be elevated in patients with injury to muscle other than cardiac muscle? Answer: CK-MB and myoglobin
⩥ Which of the following is considered an action of the hormone glucagon? Answer: Increase glycogenolysis ⩥ The classic TORCH panel of tests includes the following diseases with the exception of: Answer: Infectious mononucleosis ⩥ What color would the agar be around a colony of Staphylococcus epidermidis growing on mannitol salt agar (MSA)? Answer: Red ⩥ Based on the following results obtained against a patient's red cells, what will the genotype look like in this example? Anti-C = 4+Anti-c = 4+Anti-E = 0Anti-e = 4+Anti-D = 0 Answer: r'r ⩥ Which parasite demonstrates the following findings on a blood smear from a patient with suspected malaria? Enlarged RBCs, some with fine brownish granules
12 parasites in some cells Amoeboid structures Schüffner's dots Answer: Plasmodium vivax ⩥ When three tubes of cerebrospinal fluid are received in the laboratory they should be distributed to the various laboratory sections as follows: Answer: #1 Chemistry, #2 Microbiology, #3 Hematology
⩥ What is a workload reporting system, and why is it an important part of laboratory management? Answer: Helps in planning, developing, and maintaining efficient laboratory services with administrative and budget controls ⩥ Estrogen (ERs) and progesterone (PRs) receptors used as tumor markers are most commonly employed to provide prognostic information about: Answer: Breast cancer ⩥ At many hospitals, patients with sickle cell disease are given phenotypically matched units of blood. This policy is often used to help prevent alloimmunization to common RBC antigens in patients who are regularly transfused. A patient who regularly comes to your hospital demonstrates the following phenotype on her RBCs: C antigen positive; E antigen-negative; K antigen positive. The patient's doctor requests a single unit of crossmatched packed RBCs. Based on the antigen prevalence indicated below, how many units of ABO compatible packed RBCs will you phenotype to find one to transfuse to this patient? Antigen frequencies C antigen positive: 68% E antigen positive: 22% K antigen positive: 9% Answer: 1 unit
⩥ The most common methods for measuring bilirubin are based on the reaction of bilirubin with: Answer: Diazo reagent ⩥ Laboratory results obtained on a 47-year-old patient were as follows: WBC 51.2 x 103/μLRBC 4.27 x 106/μLHGB 12.6 g/dLHCT 36.9%PLT 403 x 103/μL Differential:50% segmented neutrophils20% bands12% lymphocytes7% monocytes1% eosinophils9% metamyelocytes1% myelocytesRBC morphology: normocytic, normochromicWBC morphology: moderate toxic granulation, slight Dohle body Which test would be MOST helpful in establishing a diagnosis in this case? Answer: Leukocyte alkaline phosphatase stain (LAP stain) ⩥ Donor and recipient blood samples must be kept for at least how long after transfusion? Answer: 7 days ⩥ A specimen for a repeat complete blood count is received in the laboratory six hours later. The sample visually appears to be much lighter in color than the original sample. The technologist questions whether both samples are from the same patient. Which of the following parameter(s) is LEAST likely to change between samples, if from the same patient, and would be most useful to determine if there is a discrepancy that may be the result of a preanalytical error in sample collection? Answer: MCV
⩥ The ultimate end product of both epinephrine and norepinephrine metabolism is: Answer: Vanillylmandellic acid (VMA) ⩥ Pseudomonas aeruginosa was isolated from a sputum specimen. Susceptibility testing was performed and the microbiologist determined that further evaluation was needed before reporting out the susceptibilities. Which of the antibiotic results would indicate a need for further evaluation? Answer: Amikacin resistant, Gentamicin or tobramycin sensitive, Carbapenem-resistant ⩥ What is the most common treatment for hemolytic disease of the fetus and newborn (HDFN) due to ABO incompatibility? Answer: Phototherapy ⩥ Complaints of pain from a patient with sickle cell disease are most likely associated with which of the following conditions/events? Answer: Vaso-occlusive crisis ⩥ The average bone marrow cellularity in a normal adult (50 years old) is: Answer: 50 ⩥ Rejuvenation solutions for donated red blood cell units may be used to improve what factor that is affected by storage lesion? Answer: 2,3 DPG
