Semmelweis Entrance Exam Medicine Biology questions, Exams of Advanced Education

Semmelweis Entrance Exam Medicine Biology questions

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2025/2026

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Semmelweis Entrance Exam Medicine
Biology questions
1.
What are carbohydrates and lipids?:
Organic compounds that are mostly composed of
three types
of atom; carbon, hydrogen and oxygen
2.
What
do
carbohydrates
do?:
provide energy, in the form of sugars like glucose and fructose,
but they
also
make
up
structures
like
cellulose,
which
form
the
cell
wall
of
plant
cells
3. What type of carbohydrate is the most important source of energy?:
mono-, di-
and poly-saccharides
4.
What
are
mono
and
disaccharides?:
polar
and
soluble
in
water
5.
What
are
polysaccharides?:
Macromolecules
resulting
from
polymerisation
(condensation)
of
sugars
and are not soluble in water
6.
Examples
of
monosaccharides:
ribose,
glucose,
fructose,
galactose
7.
What
forms
a
disaccharide?:
two
monosaccharides
linked
together
by
condensation
reactions
with
glycosidic
bonds
releasing
one
H2O
molecule
pf3
pf4
pf5
pf8
pf9
pfa
pfd
pfe
pff
pf12
pf13
pf14

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Semmelweis Entrance Exam Medicine

Biology questions

  1. What are carbohydrates and lipids?: Organic compounds that are mostly composed of three types of atom; carbon, hydrogen and oxygen
  2. What do carbohydrates do?: provide energy, in the form of sugars like glucose and fructose, but they also make up structures like cellulose, which form the cell wall of plant cells
  3. What type of carbohydrate is the most important source of energy?: mono-, di- and poly-saccharides
  4. What are mono and disaccharides?: polar and soluble in water
  5. What are polysaccharides?: Macromolecules resulting from polymerisation (condensation) of sugars and are not soluble in water
  6. Examples of monosaccharides: ribose, glucose, fructose, galactose
  7. What forms a disaccharide?: two monosaccharides linked together by condensation reactions with glycosidic bonds releasing one H2O molecule

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  1. Alpha glucose structure:
  2. Beta glucose structure:
  3. Examples of Polysaccharides: cellulose, glycogen and starch
  4. Monomer of Sucrose: glucose and fructose
  5. monomer of maltose: glucose and glucose
  6. monomer of lactose: glucose and galactose
  7. monomer of starch: glucose
  8. monomer of glycogen: glucose
  9. monomer of cellulose: glucose
  10. In animals, what carbohydrate stores energy?: glycogen
  11. What jobs do carbohydrates have other than storing energy?: structural components
  12. What differs the polysaccharides all made up of glucose?: they ditter in the arrange- ment of glucose molecules and position of the glycosidic bonds
  13. Starch arrangement: amylopectin branched, amylose linear
  14. What is galactose?: a sugar in milk
  15. What is fructose?: a sugar found in fruit and honey
  16. Main characteristic of lipids?: little to no aflnity to water, mostly hydrophobic

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  1. What is the secondary protein structure?: Beta pleated sheet and alpha helix. Hydrogen bonds between polypeptides form these structures
  2. What is the tertiary protein structure?: three dimensional conformation. Forms when a polypep- tide folds up after translation. Stabilized by intramolecular bonds between amino acids and polypeptides
  3. What is the quaternary protein structure?: linking two or more polypeptides to form a single protein
  4. What is the basic structure of DNA?: it is composed of three parts, a pentose sugar, a phosphate group and a nitrogenous base
  5. Difference in structure between DNA and RNA: RNA contains a ribose sugar instead of deoxyribose and is also single stranded as well as having Uracil as a base instead of thymine
  6. What are the two double helix strands held together by?: hydrogen bonds
  7. What are hydrogen bonds?: a special type of dipole-dipole attraction between molecules, not a covalent bond to a hydrogen atom. It results from the attractive force between a hydrogen atom covalently bonded to a very electronegative atom such as a N, O, or F atom and another very electronegative atom

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  1. Why is DNA antiparallel?: so that the paired bases can face each other
  2. what is mRNA?: Messenger RNA: Encodes amino acid sequence of a polypeptide
  3. What is tRNA?: transfer RNA. It carries amino acids around during translation.
  4. What is rRNA?: Ribosomal RNA. with ribosomal proteins, makes up the ribosomes, the organelles that translate the mRNA
  5. what is snRNA?: small nuclear RNA. with proteins, forms complexes that are used in RNA processing in eukaryotes
  6. What are enzymes?: biological catalysts. They are globular proteins that can speed up a biochemical reaction. Alternative pathway
  7. What is glycolysis?: the breakdown of glucose by enzymes, releasing energy and pyruvic acid.
  8. What is the kreb's cycle?: second stage of cellular respiration, in which pyruvic acid is broken down into carbon dioxide in a series of energy-extracting reactions
  9. What is the mechanism of ATP production in the mitochondria?: located in the inner mitochondrial membrane, allows the protons to dittuse back across the membrane to the matrix. ATP synthase uses the energy that the protons release as they dittuse down the concentration gradient to produce ATP

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  1. What is the function of the golgi apparatus?: sorts and modifies proteins that have arrived from the rough ER
  2. What is the function of ribosomes?: protein synthesis by translating mRNA
  3. What is the cytoskeleton?: a microscopic network of protein filaments and tubules in the cytoplasm of many living cells, giving them shape and coherence.
  4. What is exocytosis?: a process by which the contents of a cell vacuole are released to the exterior through fusion of the vacuole membrane with the cell membrane.
  5. What is endocytosis?: the taking in of matter by a living cell by invagination of its membrane to form a vacuole
  6. What is the function of a cell membrane?: The cell membrane regulates what enters and leaves the cell and also protects and supports the cell
  7. Cell membrane diagram:
  8. Describe the process of mitosis: - Start with: Diploid, 2N
  • Interphase: DNA replication = Dipoid, 4N
  • Prophase: Condensation of chromatin, appearance of sister chromatids
  • Metaphase: Sister chromatids align

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  • Anaphase: Sister chromatids separate, centromeres divide
  • Telophase and Cytokinesis: Two identical, diploid, daughter cells: Diploid, 2N
  1. Describe the process of meiosis: When a cell divides to form gametes:
  2. Copies of the genetic information are made
  3. The cell divides twice to form four gametes, each with a single set of chromosomes
  4. All gametes are genetically ditterent from each other Gametes join at fertilisation to restore the normal number of chromosomes. The new cell divides by mitosis. The number of cells increases. As the embryo develops, cells ditterentiate.
  5. When does crossing over occur?: prophase I of meiosis
  6. When does recombination occur in meiosis?: during prophase I, when homologous chro- mosomes line up in pairs and swap segments of DNA.
  7. What is the structure of prokaryotic cells?:
  8. Example of prokaryotic cell: E. coli
  9. Example of eukaryotic cell: plant and animal cells

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  1. What are the parts of the respiratory system?:
  2. What are the mechanisms of inhalation and exhalation?: When you inhale, the diaphragm contracts and moves downward. Through exhalation air leaves the lungs and the diaphragm relaxes
  3. How does the oxygen and CO2 exchange in the lungs occur?: Gas exchange is the delivery of oxygen from the lungs to the bloodstream, and the elimination of carbon dioxide from the bloodstream to the lungs. The walls of the alveoli share a membrane with the capillaries in which oxygen and carbon dioxide move freely between the respiratory system and the bloodstream
  4. What are the parts of the excretory system?:
  5. What are the parts of the circulatory system?:
  6. What is the function of the heart?: The heart is the most powerful muscle in the body, pumping 4,000 gallons of blood a day
  7. What is the structure of the heart?:
  8. What is blood?: fluid connective tissue
  9. What does blood contain?: Nutrients such as glucose, antibodies, carbon dioxide, heat, oxygen, urea

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  1. What are the different cell types?: Prokaryotic and Eukaryotic
  2. What is the process of cellular immune response?: the immune system's third line of defense, involving the attack of pathogens by T cells
  3. What are the three lines of defense?: First line: Natural barriers: Skin and mucous membranes Second line: Inflammation Third line: Adaptive (acquired) immunity
  4. How does blood clotting occur?: Clotting seals damaged vessels to prevent pathogenic entry
  • Injured cells and platelets release clotting factors
  • These factors convert prothrombin into thrombin
  • Thrombin converts fibrinogen (soluble) into fibrin (insoluble)
  • Fibrin forms a mesh of fibres that block the injured site - Clotting factors also cause platelets to become sticky and form a solid plug (called a clot), sealing the wound - This process of events is called a coagulation cascade
  • Clot formation in coronary arteries lead to heart attacks
  1. What is innate immunity?: Nonspecific protection against foreign substances

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  1. Describe the ovarian cycle: Eggs are formed through meiosis in ovaries 1 matures enough to be released into fallopian tubes (halfway through monthly cycle) Corpus luteum where egg used to be disintegrates unless fertilized
  2. What causes ovulation?: surge of LH

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  1. What causes menstruation?: drop in estrogen and progesterone
  2. What are the pituitary gland hormones and what are their functions?: The pituitary gland is about the size of a pea. It is located in the brain, and sits just behind the bridge of the nose. The pituitary gland is called the master gland of the endocrine system. This is because it controls many other hormone glands in the body
  3. What are the adrenal gland hormones and what are their functions?: The adrenal cortex—the outer part of the gland—produces hormones that are vital to life, such as cortisol (which helps regulate metabolism and helps your body respond to stress) and aldosterone (which helps control blood pressure)
  4. What are the thyroid gland hormones and what are their functions?: The function of the thyroid gland is to take iodine, found in many foods, and convert it into thyroid hormones: thyroxine and triiodothyronine
  5. Describe the autonomic nervous system: The autonomic nervous system is the motor sub- division of the parasympathetic nervous system that controls body activities automatically. The ANS is

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  1. What is the mechanism of vision?: The light rays emitted by various objects are captured by eyes and then send inwards. The light rays are visible wavelength are focussed on the retina through the cornea & the lens. This generates the potentials (impulses) in the rods and the cones present in the retina
  2. How does the hearing mechanism work?: Sound waves enter the outer ear and travel through the external auditory canal until they reach the tympanic membrane, causing the membrane and the attached chain of auditory ossicles to vibrate
  3. How does the olfactory system function?: involves the detection and identification of mole- cules in the air. Once detected by sensory organs, nerve signals are sent to the brain where the signals are processed
  4. What are mendel's laws?: 1. Law of Dominance
  5. Law of Segregation
  6. Law of Independent Assortment
  7. What is the overall structure of genes?: Genes are composed of deoxyribonucleic acid (DNA), except in some viruses, which have genes consisting of a closely related compound called ribonucleic acid (RNA). A DNA molecule is composed of two chains of nucleotides that wind about each other to resemble a twisted ladder
  8. What is a gene?: segment of DNA that codes for a protein

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  1. What are the levels of gene expression?: Genes that code for amino acid sequences are known as 'structural genes'. The process of gene expression involves two main stages: Transcription: the production of messenger RNA (mRNA) by the enzyme RNA polymerase, and the processing of the resulting mRNA molecule
  2. What is a frameshift mutation?: mutation that shifts the "reading" frame of the genetic message by inserting or deleting a nucleotide. The resulting protein is nonfunctional
  3. What is a missense mutation?: Point mutation in which a single nucleotide is changed, resulting in a codon that codes for a ditterent amino acid.
  4. What is a nonsense mutation?: change resulting in early stop codon
  5. What is a chromosomal mutation?: A change in the number or structure of chromosomes
  6. What is down's syndrome caused by?: trisomy 21
  7. What is turner syndrome caused by?: 45 chromosomes instead of 46
  8. What is Klinefelter syndrome caused by?: 47 chromosomes, three sex chromosomes, XXY
  9. What is edward's syndrome caused by?: Trisomy 18
  10. What is Patau syndrome caused by?: Trisomy 13

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  1. What bones are in the appendicular skeleton?: Upper Extremities -Shoulder (pectorial) girdle
  • Arm
  • Wrist
  • Hands Lower Extremities -Hip (pelvic) girdle
  • Legs
  • Ankles
  • Feet
  1. What type of hormones enter their target cells?: Being lipids, steroid hormones enter the cell by simple dittusion across the plasma membrane
  2. What type of muscle is the diaphragm?: skeletal muscle
  3. Which vitamins are soluble in water?: B and C
  4. What is pepsin?: Enzyme that breaks down proteins in the stomach
  5. What is pepsin made of?: short polypeptides linked together
  6. What is tubulin?: Hollow tubes 25 nanometers in diameter

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  1. What are centrioles?: Centrioles help organize cell division and are formed from tubulin and located near the nucleus.
  2. What is triploidy?: three sets of chromosomes
  3. What is monoploidy?: missing a chromosome in a set of chromosomes
  4. What is aneuploidy?: Abnormal number of chromosomes
  5. What is a gonosome?: synonym for sex chromosome
  6. What is autosomal?: chromosomes that are not sex chromosomes
  7. What is connective tissue?: Framework of the body, providing support and structure for the organs.
  8. What is included in connective tissue?: Loose ordinary connective tissue Adipose tissue Blood and blood forming tissues Dense ordinary connective tissue Cartilage Bone
  9. What is the epithelium?: A tissue that lines internal and external tissues in animals.