Top 300 Drugs: Indications & Mechanisms, Exams of Pharmacy

Top 300 Drugs: Indications & Mechanisms

Typology: Exams

2025/2026

Available from 02/12/2026

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Top 300 Drugs: Indications &
Mechanisms
Benzonatate - CORRECT ANSWER- - INDICATION: cough
- MECHANISM: anesthetizes stretch receptors in the respiratory tract
Codeine & Guaifenesin - CORRECT ANSWER- - INDICATION:
cough
- MECHANISM: 1) suppresses the cough reflex in the medulla
oblongata; 2) thins bronchial secretions
Promethazine & Codeine - CORRECT ANSWER- - INDICATION:
cough
- MECHANISM: 1) H1 antagonist; 2) suppresses the cough reflex in the
medulla oblongata
Promethazine and Dextromethorphan - CORRECT ANSWER- -
INDICATION: cough
- MECHANISM: 1) H1 antagonist; 2) suppresses the cough reflex in the
medulla oblongata
Albuterol - CORRECT ANSWER- - INDICATION: bronchospasm
- MECHANISM: short-acting β2 agonist
Beclomethasone - CORRECT ANSWER- - INDICATION: asthma
- MECHANISM: alters transcription of anti-inflammatory genes
Fluticasone (Nasal) - CORRECT ANSWER- - INDICATION: rhinitis
- MECHANISM: alters transcription of anti-inflammatory genes
Fluticasone (Inhalation) - CORRECT ANSWER- - INDICATION:
asthma
- MECHANISM: alters transcription of anti-inflammatory genes
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Top 300 Drugs: Indications &

Mechanisms

Benzonatate - CORRECT ANSWER- - INDICATION: cough

  • MECHANISM: anesthetizes stretch receptors in the respiratory tract Codeine & Guaifenesin - CORRECT ANSWER- - INDICATION: cough
  • MECHANISM: 1) suppresses the cough reflex in the medulla oblongata; 2) thins bronchial secretions Promethazine & Codeine - CORRECT ANSWER- - INDICATION: cough
  • MECHANISM: 1) H1 antagonist; 2) suppresses the cough reflex in the medulla oblongata Promethazine and Dextromethorphan - CORRECT ANSWER- - INDICATION: cough
  • MECHANISM: 1) H1 antagonist; 2) suppresses the cough reflex in the medulla oblongata Albuterol - CORRECT ANSWER- - INDICATION: bronchospasm
  • MECHANISM: short-acting β2 agonist Beclomethasone - CORRECT ANSWER- - INDICATION: asthma
  • MECHANISM: alters transcription of anti-inflammatory genes Fluticasone (Nasal) - CORRECT ANSWER- - INDICATION: rhinitis
  • MECHANISM: alters transcription of anti-inflammatory genes Fluticasone (Inhalation) - CORRECT ANSWER- - INDICATION: asthma
  • MECHANISM: alters transcription of anti-inflammatory genes

Fluticasone & Salmeterol - CORRECT ANSWER- - INDICATION: asthma & COPD

  • MECHANISM: 1) alters transcription of anti-inflammatory genes; 2) long-acting β2 agonist Fluticasone & Vilanterol - CORRECT ANSWER- - INDICATION: asthma & COPD
  • MECHANISM: 1) alters transcription of anti-inflammatory genes; 2) long-acting β2 agonist Budesonide - CORRECT ANSWER- - INDICATION: asthma
  • MECHANISM: alters transcription of anti-inflammatory genes Budesonide with Formoterol - CORRECT ANSWER- - INDICATION: asthma & COPD
  • MECHANISM: 1) alters transcription of anti-inflammatory genes; 2) long-acting β2 agonist Mometasone with Formoterol - CORRECT ANSWER- - INDICATION: asthma
  • MECHANISM: 1) alters transcription of anti-inflammatory genes; 2) long-acting β2 agonist Ipratropium - CORRECT ANSWER- - INDICATION: COPD & rhinitis
  • MECHANISM: muscarinic antagonist Ipratropium & Albuterol - CORRECT ANSWER- - INDICATION: COPD
  • MECHANISM: 1) muscarinic antagonist; 2) short-acting β2 agonist Umeclidinium - CORRECT ANSWER- - INDICATION: COPD
  • MECHANISM: muscarinic antagonist Umeclidinium & Vilanterol - CORRECT ANSWER- - INDICATION: COPD
  • MECHANISM: 1) muscarinic antagonist; 2) long-acting β2 agonist

Metoclopramide - CORRECT ANSWER- - INDICATION: gastroparesis, nausea, & vomiting

  • MECHANISM: dopamine antagonist Diphenoxylate & Atropine - CORRECT ANSWER- - INDICATION: diarrhea
  • MECHANISM: 1) opioid agonist; 2) muscarinic antagonist Dicyclomine - CORRECT ANSWER- - INDICATION: IBS
  • MECHANISM: muscarinic antagonist Hyoscyamine - CORRECT ANSWER- - INDICATION: IBS
  • MECHANISM: muscarinic antagonist Tolterodine - CORRECT ANSWER- - INDICATION: overactive bladder
  • MECHANISM: muscarinic antagonist Oxybutynin - CORRECT ANSWER- - INDICATION: overactive bladder
  • MECHANISM: muscarinic antagonist Solifenacin - CORRECT ANSWER- - INDICATION: overactive bladder
  • MECHANISM: muscarinic antagonist Mirabegron - CORRECT ANSWER- - INDICATION: overactive bladder
  • MECHANISM: β3 agonist Sucralfate - CORRECT ANSWER- - INDICATION: duodenal ulcer
  • MECHANISM: forms an ulcer-adherent complex Ranitidine - CORRECT ANSWER- - INDICATION: GERD
  • MECHANISM: H2 antagonist

Famotidine - CORRECT ANSWER- - INDICATION: GERD

  • MECHANISM: H2 antagonist Omeprazole - CORRECT ANSWER- - INDICATION: GERD
  • MECHANISM: PPI Esomeprazole - CORRECT ANSWER- - INDICATION: GERD
  • MECHANISM: PPI Lansoprazole - CORRECT ANSWER- - INDICATION: GERD
  • MECHANISM: PPI Dexlansoprazole - CORRECT ANSWER- - INDICATION: GERD
  • MECHANISM: PPI Pantoprazole - CORRECT ANSWER- - INDICATION: GERD
  • MECHANISM: PPI Lactulose - CORRECT ANSWER- - INDICATION: constipation
  • MECHANISM: colon osmotic agent Linaclotide - CORRECT ANSWER- - INDICATION: constipation
  • MECHANISM: guanylate cyclase agonist Finasteride - CORRECT ANSWER- - INDICATION: BPH
  • MECHANISM: 5-α-reductase inhibitor Dutasteride - CORRECT ANSWER- - INDICATION: BPH
  • MECHANISM: 5-α-reductase inhibitor Tamsulosin - CORRECT ANSWER- - INDICATION: BPH
  • MECHANISM: α1 antagonist Alfuzosin - CORRECT ANSWER- - INDICATION: BPH
  • MECHANISM: α1 antagonist
  • MECHANISM: β1 antagonist Clonidine - CORRECT ANSWER- - INDICATION: hypertension & ADHD
  • MECHANISM: α2 agonist Guanfacine - CORRECT ANSWER- - INDICATION: hypertension & ADHD
  • MECHANISM: α2 agonist Lisinopril - CORRECT ANSWER- - INDICATION: hypertension
  • MECHANISM: ACE inhibitor Lisinopril & Hydrochlorothiazide - CORRECT ANSWER- - INDICATION: hypertension
  • MECHANISM: 1) ACE inhibitor; 2) inhibits sodium and chloride reabsorption in the distal tubule Enalapril - CORRECT ANSWER- - INDICATION: hypertension
  • MECHANISM: ACE inhibitor Ramipril - CORRECT ANSWER- - INDICATION: hypertension
  • MECHANISM: ACE inhibitor Fosinopril - CORRECT ANSWER- - INDICATION: hypertension
  • MECHANISM: ACE inhibitor Quinapril - CORRECT ANSWER- - INDICATION: hypertension
  • MECHANISM: ACE inhibitor Benazepril - CORRECT ANSWER- - INDICATION: hypertension
  • MECHANISM: ACE inhibitor Losartan - CORRECT ANSWER- - INDICATION: hypertension
  • MECHANISM: ARB

Losartan & Hydrochlorothiazide - CORRECT ANSWER- - INDICATION: hypertension

  • MECHANISM: 1) ARB; 2) inhibits sodium and chloride reabsorption in the distal tubule Irbesartan - CORRECT ANSWER- - INDICATION: hypertension
  • MECHANISM: ARB Valsartan - CORRECT ANSWER- - INDICATION: hypertension
  • MECHANISM: ARB Valsartan & Hydrochlorothiazide - CORRECT ANSWER- - INDICATION: hypertension
  • MECHANISM: 1) ARB; 2) inhibits sodium and chloride reabsorption in the distal tubule Olmesartan - CORRECT ANSWER- - INDICATION: hypertension
  • MECHANISM: ARB Nifedipine - CORRECT ANSWER- - INDICATION: hypertension & angina
  • MECHANISM: calcium channel blocker Amlodipine - CORRECT ANSWER- - INDICATION: hypertension & angina
  • MECHANISM: calcium channel blocker Amlodipine & Benazepril - CORRECT ANSWER- - INDICATION: hypertension
  • MECHANISM: 1) calcium channel blocker; 2) ACE inhibitor Verapamil - CORRECT ANSWER- - INDICATION: hypertension & angina
  • MECHANISM: calcium channel blocker Diltiazem - CORRECT ANSWER- - INDICATION: hypertension & angina

Bumetanide - CORRECT ANSWER- - INDICATION: edema & hypertension

  • MECHANISM: inhibits sodium and chloride reabsorption in the Loop of Henle Hydrochlorothiazide - CORRECT ANSWER- - INDICATION: edema & hypertension
  • MECHANISM: inhibits sodium and chloride reabsorption in the distal tubule Chlorthalidone - CORRECT ANSWER- - INDICATION: edema & hypertension
  • MECHANISM: inhibits sodium and chloride reabsorption in the distal tubule Metolazone - CORRECT ANSWER- - INDICATION: edema & hypertension
  • MECHANISM: inhibits sodium and chloride reabsorption in the distal tubule Triamterene & Hydrochlorothiazide - CORRECT ANSWER- - INDICAITON: edema & hypertension
  • MECHANISM: 1) inhibits sodium and potassium exchange in the distal tubule; 2) inhibits sodium and chloride reabsorption in the distal tubule Spironolactone - CORRECT ANSWER- - INDICATION: edema, hypertension, hypokalemia, & primary hyperaldosteronism
  • MECHANISM: aldosterone antagonist Warfarin - CORRECT ANSWER- - INDICATION: embolism
  • MECHANISM: vitamin K antagonist Rivaroxaban - CORRECT ANSWER- - INDICATION: embolism
  • MECHANISM: factor Xa antagonist Apixaban - CORRECT ANSWER- - INDICATION: embolism
  • MECHANISM: factor Xa antagonist

Dabigatran - CORRECT ANSWER- - INDICAITON: embolism

  • MECHANISM: thrombin antagonist Clopidogrel - CORRECT ANSWER- - INDICATION: atherosclerosis
  • MECHANISM: platelet antagonist Cyanocobalamin - CORRECT ANSWER- - INDICATION: pernicious anemia
  • MECHANISM: DNA synthesis cofactor Folic Acid - CORRECT ANSWER- - INDICATION: megaloblastic anemia
  • MECHANISM: DNA synthesis cofactor Atorvastatin - CORRECT ANSWER- - INDICATION: hypercholesterolemia & hypertriglyceridemia
  • MECHANISM: HMG-CoA reductase inhibitor Rosuvastatin - CORRECT ANSWER- - INDICATION: hypercholesterolemia & hypertriglyceridemia
  • MECHANISM: HMG-CoA reductase inhibitor Pravastatin - CORRECT ANSWER- - INDICATION: hypercholesterolemia & hypertriglyceridemia
  • MECHANISM: HMG-CoA reductase inhibitor Simvastatin - CORRECT ANSWER- - INDICATION: hypercholesterolemia & hypertriglyceridemia
  • MECHANISM: HMG-CoA reductase inhibitor Lovastatin - CORRECT ANSWER- - INDICATION: hypercholesterolemia & hypertriglyceridemia
  • MECHANISM: HMG-CoA reductase inhibitor Ezetimibe - CORRECT ANSWER- - INDICATION: hypercholesterolemia

Terbinafine - CORRECT ANSWER- - INDICATION: fungal infections

  • MECHANISM: squalene epoxidase inhibitor Ketoconazole - CORRECT ANSWER- - INDICATION: fungal infections
  • MECHANISM: ergosterol synthesis inhibitor Fluconazole - CORRECT ANSWER- - INDICATION: fungal infections
  • MECHANISM: inhibits sterol C-14 α-demethylation by cytochrome P Clotrimazole & Betamethasone - CORRECT ANSWER- - INDICATION: topical fungal infections
  • MECHANISM: 1) permeates fungal cell wall chitin; 2) alters transcription of anti-inflammatory genes Metronidazole - CORRECT ANSWER- - INDICATION: bacterial and protozoal infections
  • MECHANISM: binds and breaks DNA Levofloxacin - CORRECT ANSWER- - INDICATION: bacterial infections
  • MECHANISM: DNA gyrase inhibitor Ciprofloxacin - CORRECT ANSWER- - INDICATION: bacterial infections
  • MECHANISM: DNA gyrase inhibitor Ciprofloxacin (Ophthalmic) - CORRECT ANSWER- - INDICATION: ophthalmic bacterial infections
  • MECHANISM: DNA gyrase inhibitor Ciprofloxacin & Dexamethasone - CORRECT ANSWER- - INDICATION: otic bacterial infections
  • MECHANISM: 1) DNA gyrase inhibitor; 2) alters transcription of anti- inflammatory genes

Ofloxacin - CORRECT ANSWER- - INDICATION: ophthalmic bacterial infections

  • MECHANISM: DNA gyrase inhibitor Trimethoprim & Polymyxin - CORRECT ANSWER- - INDICATION: ophthalmic bacterial infections
  • MECHANISM: 1) dihydrofolate reductase inhibitor; 2) interacts with bacterial cell membrane phospholipids Sulfamethoxazole & Trimethoprim - CORRECT ANSWER- - INDICATION: bacterial infections
  • MECHANISM: 1) PABA antagonist; 2) dihydrofolate reductase inhibitor Mupirocin - CORRECT ANSWER- - INDICATION: topical bacterial infections
  • MECHANISM: isoleucyl-tRNA synthetase inhibitor Azithromycin - CORRECT ANSWER- - INDICATION: bacterial infections
  • MECHANISM: 50S ribosomal subunit inhibitor Clarithromycin - CORRECT ANSWER- - INDICATION: bacterial infections
  • MECHANISM: 50S ribosomal subunit inhibitor Clindamycin - CORRECT ANSWER- - INDICATION: bacterial infections
  • MECHANISM: 50S ribosomal subunit inhibitor Doxycycline Hyclate - CORRECT ANSWER- - INDICATION: bacterial infections
  • MECHANISM: 30S ribosomal subunit inhibitor Doxycycline Monohydrate - CORRECT ANSWER- - INDICATION: bacterial infections
  • MECHANISM: 30S ribosomal subunit inhibitor

Chlorhexidine - CORRECT ANSWER- - INDICATION: gingivitis

  • MECHANISM: disrupts the bacterial cell membrane Carisoprodol - CORRECT ANSWER- - INDICATION: muscle spasms
  • MECHANISM: unknown Methocarbamol - CORRECT ANSWER- - INDICATION: muscle spasms
  • MECHANISM: unknown Baclofen - CORRECT ANSWER- - INDICATION: muscle spasms
  • MECHANISM: unknown Cyclobenzaprine - CORRECT ANSWER- - INDICATION: muscle spasms
  • MECHANISM: unknown Tizanidine - CORRECT ANSWER- - INDICATION: muscle spasms
  • MECHANISM: α2 agonist Orphenadrine - CORRECT ANSWER- - INDICATION: muscle spasms
  • MECHANISM: muscarinic antagonist Benztropine - CORRECT ANSWER- - INDICATION: Parkinson's disease
  • MECHANISM: muscarinic antagonist & H1 antagonist Carbidopa & Levodopa - CORRECT ANSWER- - INDICATION: Parkinson's disease
  • MECHANISM: 1) DOPA decarboxylase inhibitor; 2) metabolized to dopamine Ropinirole - CORRECT ANSWER- - INDICATION: Parkinson's disease
  • MECHANISM: D2 agonist & D3 agonist

Pramipexole - CORRECT ANSWER- - INDICATION: Parkinson's disease

  • MECHANISM: D3 agonist Memantine - CORRECT ANSWER- - INDICATION: Alzheimer's disease
  • MECHANISM: NMDA antagonist Donepezil - CORRECT ANSWER- - INDICATION: Alzheimer's disease
  • MECHANISM: acetylcholinesterase inhibitor Gabapentin - CORRECT ANSWER- - INDICATION: seizures & neuralgia
  • MECHANISM: unknown Pregabalin - CORRECT ANSWER- - INDICATION: seizures & neuralgia
  • MECHANISM: unknown Levetiracetam - CORRECT ANSWER- - INDICATION: seizures
  • MECHANISM: unknown Topiramate - CORRECT ANSWER- - INDICATION: seizures
  • MECHANISM: unknown Primidone - CORRECT ANSWER- - INDICATION: seizures
  • MECHANISM: GABA(A) agonist Phenobarbital - CORRECT ANSWER- - INDICATION: seizures
  • MECHANISM: GABA(A) agonist Phenytoin - CORRECT ANSWER- - INDICAITON: seizures
  • MECHANISM: sodium channel blocker Carbamazepine - CORRECT ANSWER- - INDICAITON: seizures
  • MECHANISM: sodium channel blocker
  • MECHANISM: D1 antagonist, D2 antagonist, 5-HT1 antagonist, 5-HT antagonist, H1 antagonist, α1 antagonist, & α2 antagonist Olanzapine - CORRECT ANSWER- - INDICATION: schizophrenia & bipolar disorder
  • MECHANISM: dopamine antagonist, 5-HT2 antagonist, H1 antagonist, α1 antagonist, & muscarinic antagonist Prochlorperazine - CORRECT ANSWER- - INDCAITON: schizophrenia, nausea, & vomiting
  • MECHANISM: dopamine antagonist Buspirone - CORRECT ANSWER- - INDICATION: anxiety
  • MECHANISM: unknown Alprazolam - CORRECT ANSWER- - INDICATION: anxiety
  • MECHANISM: GABA(A) agonist Clonazepam - CORRECT ANSWER- - INDICATION: anxiety & seizures
  • MECHANISM: GABA(A) agonist Diazepam - CORRECT ANSWER- - INDICATION: anxiety, seizures, & muscle spasms
  • MECHANISM: GABA(A) agonist Lorazepam - CORRECT ANSWER- - INDICATION: anxiety, insomnia, seizures, & to sedate
  • MECHANISM: GABA(A) agonist Temazepam - CORRECT ANSWER- - INDICATION: insomnia
  • MECHANISM: GABA(A) agonist Zaleplon - CORRECT ANSWER- - INDICATION: insomnia
  • MECHANISM: GABA(A) agonist Zolpidem - CORRECT ANSWER- - INDICATION: insomnia
  • MECHANISM: GABA(A) agonist Eszopiclone - CORRECT ANSWER- - INDICATION: insomnia
  • MECHANISM: GABA(A) agonist Modafinil - CORRECT ANSWER- - INDICATION: narcolepsy
  • MECHANISM: unknown Amphetamine & Dextroamphetamine Salts - CORRECT ANSWER- - INDICATION: ADHD & narcolepsy
  • MECHANISM: releases pre-synaptic norepinephrine and dopamine Lisdexamfetamine - CORRECT ANSWER- - INDICATION: ADHD
  • MECHANISM: releases pre-synaptic norepinephrine and dopamine Methylphenidate - CORRECT ANSWER- - INDICATION: ADHD & narcolepsy
  • MECHANISM: NET blocker & DAT blocker Dexmethylphenidate - CORRECT ANSWER- - INDICATION: ADHD
  • MECHANISM: NET blocker & DAT blocker Atomoxetine - CORRECT ANSWER- - INDICATION: ADHD
  • MECHANISM: NET blocker Vilazodone - CORRECT ANSWER- - INDICATION: depression
  • MECHANISM: 5-HT1 partial agonist & SERT inhibitor Trazodone - CORRECT ANSWER- - INDICATION: depression
  • MECHANISM: 5-HT2 antagonist & SERT inhibitor Citalopram - CORRECT ANSWER- - INDICATION: depression
  • MECHANISM: SSRI Escitalopram - CORRECT ANSWER- - INDICATION: depression
  • MECHANISM: SSRI