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An overview of the genetic code, focusing on the structure of triplet codons, reading frames, code degeneracy, and the roles of trnas, ribosomes, and amino acid attachment. It also discusses the historical perspective and differences between prokaryotic and eukaryotic systems.
Typology: Study notes
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TerminationTranslocationPeptide bond formationBindingElongationShine-Dalgarno sequenceInitiationRibosome structureAminoacylationAnticodon, wobble positionStructuretRNACode degeneracyReading framesNonoverlappingTriplet codonsGenetic code Overview
AUGInitiation
UGAUAGUAATermination
Rest have multiple --2 have 1 codon in 3rd baseto changesmostly duedegenerateis genetic code
Amino acid attachment
d180 Å
Pre-2000 view
site is 18 Å from any protein!Puromycin inhibitor in active
(bases)rRNAProtein (anticodons)tRNAs 50S
mRNA codonrRNAProtein
50S/30S complex