Genetic Code: Structure, Function, and Degeneracy, Study notes of Chemistry

An overview of the genetic code, focusing on the structure of triplet codons, reading frames, code degeneracy, and the roles of trnas, ribosomes, and amino acid attachment. It also discusses the historical perspective and differences between prokaryotic and eukaryotic systems.

Typology: Study notes

Pre 2010

Uploaded on 09/17/2009

koofers-user-k1y
koofers-user-k1y 🇺🇸

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Translation Mon-Wed 4/27-29
Overview
Genetic code
Triplet codons
Nonoverlapping
Reading frames
Code degeneracy
tRNAStructure
Anticodon, wobble position
Aminoacylation
Ribosome structure
Initiation
Shine-Dalgarno sequence
Elongation
Binding
Peptide bond formation
Translocation
Termination
pf3
pf4
pf5
pf8
pf9
pfa
pfd
pfe
pff
pf12
pf13
pf14
pf15
pf16
pf17
pf18

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Translation

Mon-Wed 4/27-

TerminationTranslocationPeptide bond formationBindingElongationShine-Dalgarno sequenceInitiationRibosome structureAminoacylationAnticodon, wobble positionStructuretRNACode degeneracyReading framesNonoverlappingTriplet codonsGenetic code Overview

AUGInitiation

UGAUAGUAATermination

Rest have multiple --2 have 1 codon in 3rd baseto changesmostly duedegenerateis genetic code

Amino acid attachment

d180 Å

Pre-2000 view

site is 18 Å from any protein!Puromycin inhibitor in active

(bases)rRNAProtein (anticodons)tRNAs 50S

mRNA codonrRNAProtein

50S/30S complex