Unit 2 Evidence base paper, Papers of Nursing

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Introduction to Evidence Practice Problem Paper Michelle McDaniel Herzing University NU- Research Methods and Evidence-Based Practice Dr. Charlene Romer November 15, 2020

Residents of House of Peace Group Home diagnoses with Schizophrenia that develops metabolic syndrome while receiving first-generation antipsychotic versus patients than receiving second- generation antipsychotic in 5 years Life expectancy in schizophrenia patients is about 20 years shorter than the general population (Misiak,2014). Metabolic syndrome is a leading cause of morbidity and mortality in patients with Schizophrenia, with a prevalence rate double than of nonpsychiatric populations (Riordan,2011). Riordan, 2011 states that the amount of evidence suggesting a link between atypical antipsychotic medications and metabolic syndrome. Kioko et al. (2016) stress the importance of screening for metabolic syndrome on patients with serious mental illness managed with second-generation antipsychotic medication.Life expectancy in schizophrenia patients is about 20 years shorter in comparison with the general population (Misiak,2014). Metabolic syndrome is a leading cause of morbidity and mortality in patients with schizophrenia, with a prevalence rate double than of nonpsychiatric populations (Riordan,2011). Riordan, 2011 states than the amount of evidence suggesting a link between atypical antipsychotic medications and metabolic syndrome. Kioko et. Al. (2016) stress the importance of screening for metabolic syndrome on patients with serious mental illness managed with second generation antipsychotic medication. Metabolic syndrome has become an essential element in psychiatric discussions. Antecedents of metabolic syndrome go as far as 2005 by Straker et. Al. The American Journal of Psychiatry was the source of this new conversation. Metabolic Syndrome includes but is not limited to weight gain, diabetes, and hyperlipidemia (Keithner, 2006). Metabolic syndrome brings a series of cardiovascular, diabetes, and diabetes complications. Keithner in 2006 states that atypical antipsychotic agents cause these effects.was the source of this new conversation. Metabolic Syndrome includes but is not limited to weight gain, diabetes, and hyperlipidemia (Keithner, 2006). The metabolic syndrome brings a series

References Misiak, B., Frydecka, D., Łaczmański, Ł., Ślęzak, R., & Kiejna, A. (2014). Effects of second-generation antipsychotics on selected markers of one-carbon metabolism and metabolic syndrome components in first-episode schizophrenia patients. European Journal of Clinical Pharmacology , 70 (12), 1433–1441. https://doi.org/10.1007/s00228-014-1762- Riordan, H. J., Antonini, P., & Murphy, M. F. (2011). Atypical Antipsychotics and Metabolic Syndrome in Patients with Schizophrenia: Risk Factors, Monitoring, and Healthcare Implications. American Health & Drug Benefits , 4 (5), 292–301. Keltner NL. (, 2006). Biological perspectives. Metabolic syndrome: Schizophrenia and atypical antipsychotics. Perspectives in Psychiatric Care , 42 (3), 204–207. https://doi.org/10.1111/j.1744- 6163.2006.00073.x