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WGU D116 ADVANCED PHARMACOLOGY OA
2026-2027 EXAM A&B 500+ QUESTIONS AND
DETAILED ANSWERS - JUST RELEASED
WGU D116 ADVANCED PHARMACOLOGY OBJECTIVE ASESEMENT
EXAM
Insulin glargine is prescribed for a hospitalized patient who has diabetes. When should this drug be administered?
- Approximately 15 to 30 minutes before each meal
- After meals and at bedtime
- In the morning and at 4:00 PM
- Once daily at bedtime
- Once daily at bedtime Correct! Insulin glargine is indicated for once-daily subcutaneous administration to treat adults and children with type 1 diabetes and adults with type 2 diabetes. According to the package labeling, the once-daily injection should be given at bedtime.
A patient who has traveler's diarrhea asks the provider about using loperamide to stop the symptoms. What should the provider tell the patient about this drug?
- "Loperamide is used for moderate to severe symptoms only."
- "Loperamide is only effective to treat certain infectious agents."
- "Loperamide use may prolong symptoms by slowing peristalsis."
- "Loperamide is useful as a prophylaxis to prevent symptoms."
- Loperamide use may prolong symptoms by slowing peristalsis Correct! Loperamide is a nonspecific antidiarrheal that slows peristalsis, which may delay transit of the causative organism and prolong the infection. 1
- Beta-blockers can mask the symptoms of hypoglycemia Correct! Beta-blockers can delay awareness of and response to hypoglycemia by masking signs associated with stimulation of the sympathetic nervous system (e.g., tachycardia, palpitations) that hypoglycemia normally causes. Furthermore, beta blockade impairs glycogenolysis, which is one means by which the body can counteract a fall in blood glucose; beta-blockers, therefore, can worsen insulin-induced hypoglycemia. The provider assesses a newly diagnosed patient for short-term complications of diabetes. What should this assessment include?
- Cranial nerve testing for peripheral neuropathy
- Auscultation of the carotids for bruits associated with atherosclerosis
- Evaluation for hyperglycemia, hypoglycemia, and ketoacidosis
- Pedal pulse palpation for arterial insufficiency
- Eval of hyperglycemia, hypoglycemia, and ketoacidosis are all short-term complications Correct! High blood sugar, low blood sugar, and ketoacidosis are short-term complications of diabetes. Which agent works to reduce hyperglycemia in people with T1DM by increasing endogenous GLP-1?
- Empagliflozin
- 70/30 mix
- No insulin should be administered
- Lispro
- Lispro Regular insulin (Lispro) is indicated for sliding scale coverage and with that high of a BS it is indicated to give A patient arrives in the emergency department with a heart rate of 128 beats per minute and a temperature of 105°F. The patient's skin feels hot and moist. The free T4 level is 4 ng/dL, the free T level is 685 pg/dL, and the TSH level is 0.1 microunits per mL. What should the provider caring for this patient order?
- Intravenous levothyroxine
- Iodine-131 (131I)
- Propylthiouracil (PTU)
- Methimazole
- Prophylthiouracil (PTU) Correct! Propylthiouracil is used for patients experiencing thyroid storm, and this patient is showing signs of this condition. 5
A patient has been taking levothyroxine for several years and reports that for the past two weeks, the drug does not seem to work as well as before. What should the provider do?
- Tell the patient to try taking the medication with food
- Expect the patient to have an elevated temperature and tachycardia
- Suggest that the patient begin taking calcium supplements
- Ask the patient when the prescription was last refilled
- Ask the pt when the prescription was last refilled Correct! Not all levothyroxine preparations have the same drug bioavailability; therefore, if a patient is experiencing differing effects, the pharmacist may have switched brands. Asking a patient about a recent refill may help explain why the drug has different effects. A healthcare professional is teaching a patient who will begin taking methimazole for Graves' disease about the medication. Which statement by the patient indicates understanding of the teaching?
- "I should report a sore throat or fever to my provider if either occurs."
- "Because of the risk for liver toxicity, I will need frequent liver function tests."
- "I will need a complete blood count every few months."
- "It is safe to get pregnant while taking this medication." 1."I should report a sore throat or fever to my provider if either occurs" Correct! Agranulocytosis is rare but can occur with methimazole, so patients should report signs of infection, such as a sore throat or fever. Which statement by a patient about to begin taking orlistat for weight loss therapy indicates an understanding of this drug's actions?
- "I can eat as much as I want and still lose weight."
- "If I take the drug four times daily instead of twice daily, I will lose weight faster."
- "If I take a bulk-forming laxative, I can reduce the incidence of fecal incontinence."
- "I should avoid fat-soluble vitamin supplements while taking this drug."
- "If I take a bulk-forming laxative, I can reduce the incidence of fecal incontinence" Correct! Because orlistat reduces fat absorption, stools often are fatty or oily, and fecal incontinence can occur. Bulk-forming laxatives can help with this side effect. A patient who has received a prescription for orlistat for weight loss asks the provider how the drug works. What should the provider tell the patient about orlistat?
Which medication should the provider discuss with the patient?
- Mucosal protectants
- Histamine-2 receptor antagonists
- Antibiotics
- Proton pump inhibitors
- Proton pump inhibitors Correct! Patients taking NSAIDs should use proton pump inhibitors for ulcer prophylaxis. A patient is diagnosed with peptic ulcer disease (PUD). The patient is otherwise healthy. The provider learns that the patient does not smoke and that he drinks one or two glasses of wine with meals once a week. Which drugs should the provider prescribe?
- Amoxicillin, clarithromycin, and omeprazole
- Tetracycline, cimetidine, and lansoprazole
- Amoxicillin, metronidazole, and cimetidine
- Clarithromycin, metronidazole, and omeprazole 9
1.Amoxicillin, clarithromycin, omeprazole Correct! The regimen recommended for the treatment of PUD includes two antibiotics and an antisecretory agent. Amoxicillin, clarithromycin, and omeprazole would meet this recommendation. A long-term patient of yours recently had stents placed in her left anterior descending artery (LAD). Her cardiologist put her on clopidogrel. She has been taking omeprazole for years for acid indigestion, and her cardiologist told her it has a drug interaction with her new medication. She agrees to change drugs for her heartburn. What drug should the provider prescribe?
- Sucralfate 500 mg BID
- Pantoprazole 20 mg QD
- Famotidine 2 mg QD
- Calcium carbonate 500 mg
- Famotidine (pepsid) 2 mg QD Correct! Famotidine suppresses acid production by blocking the H2A pathway. A patient reports taking an oral bisacodyl laxative for several years. The provider has suggested discontinuing the laxative, but the patient is unsure how to do this. What should the provider tell the patient to do?
- Switch to a bulk-forming laxative, such as methylcellulose
- Withdraw from the laxative slowly to avoid a rebound constipation effect
- Stop taking the oral laxative and use a suppository until normal motility resumes
- Stop taking the laxative immediately and expect no stool for several days
- Stop taking the laxative immediately and expect no stool for several days Correct! The first step in breaking a laxative habit is abrupt cessation of laxative use. Bowel movements will be absent for several days after laxative withdrawal. A provider is taking a history on a clinic patient who reports being constipated. Upon further questioning, the provider learns that the patient's last stool was four days ago; that it was of normal, soft consistency; and that the patient defecated without straining. The patient's abdomen is not distended, and bowel sounds are present. The patient reports usually having a stool every one to two days. What should the provider do?
- Ask about recent food and fluid intake
- Recommend a bulk laxative
- Discuss the use of polyethylene glycol
- Suggest using a bisacodyl suppository
Correct! Systemic absorption of senna, followed by renal excretion, may impart a harmless yellowish-brown or pink color to the urine. A healthcare professional is discussing the use of immunosuppressants for the treatment of inflammatory bowel disease (IBD) with a group of nursing students. Which statement by a student indicates understanding of the teaching?
- "Azathioprine helps induce rapid remission of IBD."
- "Methotrexate is used long term to maintain remission of IBD."
- "Cyclosporine can be used to induce remission of IBD."
- "Cyclosporine does not have serious adverse effects." 3."Cyclosporine can be used to induce remission of IBD" Correct! Can be given IV to induce rapid remission of IBD Which statement is correct about the contrast between acarbose and miglitol?
- Miglitol has no gastrointestinal side effects.
- Miglitol is less effective in African-American patients.
- With miglitol, sucrose can be used to treat hypoglycemia.
- Miglitol has not been associated with hepatic dysfunction. 13
4.Miglitol has not been associated with hepatic dysfunction Correct! Unlike acarbose, miglitol has not been associated with hepatic dysfunction. A patient with type 1 diabetes who takes insulin reports taking propranolol for hypertension. Why should the provider be concerned?
- Propranolol increases insulin requirements because of receptor blocking.
- The beta-blocker can mask the symptoms of hypoglycemia.
- Using the two agents together increases the risk of ketoacidosis.
- The beta-blocker can cause insulin resistance. 2.The BB can mask the symptoms of hypoglycemia Correct! Beta-blockers can delay awareness of and response to hypoglycemia by masking signs associated with the stimulation of the sympathetic nervous system (e.g., tachycardia, palpitations) that hypoglycemia normally causes. Furthermore, beta blockade impairs glycogenolysis, which is one means by which the body can counteract a fall in blood glucose. Beta-blockers, therefore, can worsen insulin-induced hypoglycemia. A patient in her twenties with Graves' disease who takes methimazole tells her provider that she is trying to conceive and asks about disease management during pregnancy. How should the provider respond?
