WGU D116 Advanced Pharmacology OA Exam 2026–2027 350 Questions and Answers (JUST RELEASED), Exams of Pharmacology

WGU D116 Advanced Pharmacology OA Exam 2026–2027 350 Questions and Answers (JUST RELEASED) is a fully updated and comprehensive study resource for students preparing for the WGU D116 Objective Assessment (OA). This complete guide includes 350 exam-style questions with verified answers, covering essential topics such as advanced pharmacology principles, drug classifications, mechanisms of action, therapeutic uses, adverse effects, drug interactions, pharmacokinetics and pharmacodynamics, and clinical application in patient care. Designed as a fast-review WGU D116 study guide and test bank, it helps students reinforce critical pharmacology knowledge, master exam concepts, reduce anxiety, and confidently pass the WGU D116 OA Exam on the first attempt. Ideal for WGU exam prep, nursing pharmacology certification study, and clinical pharmacology practice, this resource ensures efficient learning and total readiness for success.

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WGU D116 ADVANCED PHARMACOLOGY OA
EXAM 350 QUESTIONS AND ANSWERS LATEST
JUST RELEASED
A 34-year-old patient comes to a clinic complaining of pain in the left shoulder. The advanced
practice registered nurse (APRN) assesses the patient and notices that the patient has a limited
range of motion in the shoulder due to swelling. The APRN determines that the patient should
be prescribed a medication that treats peripheral nervous system disorders.
Which medication has the APRN prescribed?
Naproxen
Metoclopramide Hcl
Sumatriptan
Acetaminophen - ANSWER-Naproxen
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WGU D116 ADVANCED PHARMACOLOGY OA

EXAM 3 5 0 QUESTIONS AND ANSWERS LATEST

JUST RELEASED

A 34-year-old patient comes to a clinic complaining of pain in the left shoulder. The advanced practice registered nurse (APRN) assesses the patient and notices that the patient has a limited range of motion in the shoulder due to swelling. The APRN determines that the patient should be prescribed a medication that treats peripheral nervous system disorders. Which medication has the APRN prescribed? Naproxen Metoclopramide Hcl Sumatriptan Acetaminophen - ANSWER-Naproxen

A 32-year-old female presents to an advanced practice registered nurse (APRN) with severe nausea and vomiting during pregnancy and requires pharmaceutical therapy. The APRN knows that some medication solutions should be avoided during pregnancy. Which medication falls into this category? Metoclopramide Chenodiol Prochlorperazine Ondansetron - ANSWER-Chenodiol A 35-year-old female who is a nonsmoker is happy with her combined oral hormonal contraceptive; however, she often forgets to take her pills and would like to discuss other options. She would also prefer to avoid any contraceptive that must be inserted into her body. Which medication should be recommended for this patient? Spermicide Transdermal patch Subdermal implant Vaginal IUD - ANSWER-Transdermal patch

Polar Protein-bound Lipid-soluble - ANSWER-Lipid-soluble A 40-year-old female is diagnosed with acute pyelonephritis with symptoms of fever, chills, severe flank pain, dysuria, urinary frequency, and urinary urgency. The patient is prescribed levofloxacin for 14 days. Which bacterium is being treated in this patient? Pseudomonas aeruginosa Borrelia burgdorferi Staphylococcus aureus Escherichia coli - ANSWER-Escherichia coli A 42 - year-old female asks an advanced practice registered nurse (APRN) for help with weight loss. Her current body mass index (BMI) is 33. Which goal is realistic for this patient? Target weight loss of 20%-25% in six months Reaching target body mass index (BMI) in one month

Reaching target body mass index (BMI) in three months Target weight loss of 10%-15% in six months - ANSWER-Target weight loss of 10%-15% in six months A 16-year-old female presents to a clinic to discuss contraception. She would like to start an oral contraceptive and has no contraindications for estrogen. She also asks an advanced practice registered nurse (APRN) if there is anything she can take to help with her acne.Which FDA-approved medication will specifically manage both issues? - ANSWER-NO Norethindrone NO Levonorgestrel NO Desogestrel YES Drospirenone Incorrect. This is a second-generation combined oral contraceptive that does not work as both an oral contraceptive and acne control. A 20 - year-old patient with cancer is admitted to a medical surgical floor with diarrhea. The stool cultures return positive for Clostridium difficile. Which antibiotic should be prescribed for this patient? Metronidazole Ciprofloxacin Doxycycline Gentamicin - ANSWER-Metronidazole

Diphenhydramine Hydroxyzine Incorrect. This drug is used to treat sleeplessness and would not be a good candidate for this patient due to causing drowsiness. Correct! This is a second-generation antihistamine that has low to no potential to cause drowsiness. A 30 - year-old patient presents to a primary care clinic with a history of anxiety. The advanced practice registered nurse reviews the mechanism of action by which many neuropharmacological agents act and decides to prescribe citalopram. What is the mechanism of action of this medication? - ANSWER-YES Influences receptor activity on target cells Correct! This medication influences the activity in the receptors, and it targets cells. A 30-year-old patient with a diagnosis of paranoid schizophrenia has been living in a long-term mental health institute. The patient is getting ready to be discharged into a group-home setting that has no medical personnel on site. The patient has been noncompliant with taking oral medication in the past and is in need of an antipsychotic. A case manager is working on a plan to help the patient stay compliant with medication. Which method should be used to meet this goal?

Reminder phone call Home health Monthly injections Automatic pill box - ANSWER-Monthly injections A 32 - year-old female is discussing contraceptive options with an advanced practice registered nurse (APRN). The patient is currently taking an oral contraceptive pill and has no contraindications to estrogen therapy. She tells the APRN that she is happy with the pill because it helps her skin but really does not like having to take something every day. She is planning on getting pregnant in 10-12 months when she is done with her graduate degree. Which recommendation should the APRN make for this patient? Sub-dermal etonogestrel implant Intrauterine device Vaginal contraceptive ring Continue oral contraceptive pill - ANSWER-Vaginal contraceptive ring A 42-year-old patient suffering from pain due to cancer comes to a clinic and visits with the advanced practice registered nurse (APRN). The APRN previously had prescribed morphine to

Correct! Due to the patient's failed attempts at both lifestyle modifications and the use of medications, it is advisable to discuss the option of bariatric surgery. A 45 - year-old patient with a diagnosis of blastomycosis is in a clinic for treatment. Which antifungal should be prescribed for this patient? - ANSWER-Flucytosine YES Itraconazole Voriconazole NO Fluconazole Incorrect. Fluconazole is an antifungal, but it does not treat blastomycosis. Correct! Itraconazole is one of the two antifungals that can treat blastomycosis. A 45-year-old woman with a family history of osteoporosis is requesting to begin a vitamin D supplement. Her current vitamin D level is 20 ng/mL.Which dosage of vitamin D is appropriate for this patient? - ANSWER-YES 600 IU/day 500 IU/day 300 IU/day 400 IU/day Correct! The daily dose is correct for this patient.

A 47-year-old female presents to a clinic to discuss the management of hot flashes. She had a hysterectomy three years ago but still has her ovaries. She tells an advanced practice registered nurse (APRN) that the hot flashes are extremely bothersome to her and would like to start estradiol because this medication worked well for her sister. She tells the APRN that she smokes occasionally but is trying to quit. Which medication is contraindicated for this patient? Escitalopram Oral estrogen Gabapentin Clonidine - ANSWER-Correct Oral estrogen A 47-year-old male is brought to an emergency department with lacerations to the forearm. After applying lidocaine as local anesthetic, the patient states he feels like he may pass out and is sweating profusely. Which action by the patient's advanced practice registered nurse should be taken first? Reassure the patient the symptoms are anxiety related Assess for acute lidocaine toxicity Identify this as a normal vasovagal response Recognize this as an allergic reaction - ANSWER-Assess for acute lidocaine toxicity

nose. An advanced practice registered nurse wishes to prescribe a medication to control allergies but is concerned about drug interactions. Which medication should be considered? - ANSWER-Zileuton YES Montelukast Zafirlukast NO Cimetidine Incorrect. This is an H2 antagonist that increases theophylline levels. Correct! This is used to help reduce the effects of an asthma attack. A 53 - year-old female who is para 2 and gravida 2 (P2G2) presents to a clinic for a consultation on management of hot flashes. She is interested in treatment to help manage her symptoms since they are affecting her quality of life and causing sleep difficulty. She has well-controlled hypertension and is currently taking lisinopril 10 mg qd. She denies any personal history of blood clots. Occasionally, the patient takes ibuprofen as needed for headaches and had a migraine with an aura one time when she was a teenager. She still has her uterus and ovaries. Which medication is the safest initial medication to use to manage this patient's symptoms? Zolpidem Escitalopram Clonazepam

Estradiol - ANSWER-Escitalopram A 58 - year-old male patient presents to a clinic with rheumatoid arthritis (RA). An advanced practice registered nurse plans to prescribe leflunomide to treat this condition.Which laboratory screening test is recommended prior to starting this medication? - ANSWER-YES Tuberculosis Cholesterol Diabetes Influenza Correct! Leflunomide may increase the risk for serious infection. The drug is immunosuppressive and can suppress the bone marrow. A 68-year-old patient has chronic pain due to a workplace back injury. At times, the patient suffers from uncontrollable pain. The patient also has a history of chronic bowel obstructions. The patient uses a combination of nonpharmacological treatments to control pain, but from time to time, the pain becomes uncontrollable. The advanced practice registered nurse (APRN) decides to prescribe a medication that will help with the pain without increasing the risk of constipation. What should the APRN prescribe? An agonist-antagonist opioid A pure opioid agonist

Which professional in the nursing home should the APRN contact to help with this plan? - ANSWER-NO The nurse who serves as the house supervisor The nurse who works on the long-term care unit YES The nurse who works on the Medicare unit The nurse who provides facility education Incorrect. The nursing supervisor is not the person to complete the care planning process. Correct! The nurse to nurse report to the correct unit will ensure the patient has the best possible outcome. This prevents wrong information from being passed on if calling the wrong unit. A 69 - year-old female patient comes to a primary care clinic for her annual wellness visit. During the assessment, the patient reports having difficulty with bruising and does not know how the bruises have occurred. The woman's hair and skin are drier than normal, she has had several nosebleeds recently, and the woman noticed a small cut took a long time to heal. The patient also admitted her diet was poor lately because she recently retired, and her income does not support the purchase of fresh fruits and vegetables. A finger stick glucose level was within normal limits at 82 mg/dL. The following orders are recommended: blood work, including CBC, BMP, and HgbA1C dietitian consult vitamin C supplement (daily requirement level for patient)

What is the recommended daily requirement for this supplement? - ANSWER- 75 mg per day A 70-year-old male calls a clinic complaining of chest pain that started after having sexual activity. He took sildenafil 50 mg about eight hours ago. He has nitroglycerin 0.3 mg on hand. How should the advanced practice registered nurse respond? - ANSWER-Do not take the nitroglycerin and call 911 Taking the medications together can cause a serious drop in blood pressure leading to cardiovascular collapse. A 72-year-old female presents to a clinic with a history of osteoporosis. While examining the patient, an advanced practice registered nurse (APRN) notices that the patient has a limping gait. The patient informs the APRN that she sustained a fall at home while getting out of the bathtub three days before. The patient states that she grabbed her side rails and landed on her back. The APRN has decided to order X-rays to assess for fractures.What are the most common sites for fractures in a patient with this profile? - ANSWER-Shoulder, wrist, and leg YES Spine, wrist, and hip Neck, arm, and hip Neck, leg, and hand Correct! The mechanism of injury is correct for these injury sites.

A 75 - year-old patient comes to an emergency room after eating shellfish. He presents with shortness of breath, swollen eyes, and hives. The patient was given a dose of epinephrine intravenously and is stable enough to discharge. Which other medication should the patient be placed on to prevent a second reaction? Phenobarbital Hydrocodone Atropine sulfate Cetirizine - ANSWER-Cetirizine A 76 - year-old patient was discharged from the nursing home following a rehabilitation stay for a right-knee replacement. The patient is seeing an advanced practice registered nurse (APRN) for the first time following discharge to review the care plan and medication regimen. The patient presented with several pill bottles that appeared to be half full, which is accurate for the time frame between discharge and the appointment today. However, when completing the assessment, the APRN finds the patient's blood sugar is 216. Which question should be asked about the pill bottles? "Are you taking your medication correctly?" "Why are your pill bottles half full but your blood sugar is so high?" "Your lab work indicates you are not taking your medication correctly. What are you doing?"

"Can you review with me how often you are taking each of your medications?" - ANSWER-"Can you review with me how often you are taking each of your medications?" A 78 - year-old woman is diagnosed with chronic open-angle glaucoma. She has a past history of first-degree atrioventricular block and bradycardia. Which medication should be avoided by this patient? Timolol Pilocarpine Dorzolamide Acetazolamide - ANSWER-Timolol A 94-year-old patient is admitted to a hospital through an emergency department from a nursing home one week after being discharged to the nursing home due to documented altered mental status. Medications ordered at the time of discharge included warfarin, potassium, a multivitamin, hydrochlorothiazide, and PRN pain medication. The current medication list differs from the list documented one week ago. Which member of the interprofessional care team should be consulted to obtain accurate medication information? - ANSWER-Nursing home assistant director of nursing Hospital emergency department physician YES Nursing home discharge planner