



Study with the several resources on Docsity
Earn points by helping other students or get them with a premium plan
Prepare for your exams
Study with the several resources on Docsity
Earn points to download
Earn points by helping other students or get them with a premium plan
A comprehensive set of questions and answers related to alterations in immunity and inflammation. It covers key concepts such as immunologic homeostasis, alloimmunity, hypersensitivity, allergy, and the different types of hypersensitivity reactions. The document also includes questions about the development of type i hypersensitivity responses and the mechanisms of autoimmunity. It is a valuable resource for students studying immunology and related fields.
Typology: Exams
1 / 5
This page cannot be seen from the preview
Don't miss anything!




Immunologic homeostasis - CORRECT ANSWERS Steady state of tolerance to self-antigens or lack of immune reaction against environmental antigens Alloimmunity - CORRECT ANSWERS Immune system of one individual produces an immunologic reaction against tissues of another individual Hypersensitivity - CORRECT ANSWERS Altered immunologic response to an antigen that results in disease or damage to the host Allergy - CORRECT ANSWERS Deleterious effects of hypersensitivity to environmental antigens An individual is ______ when an adequate amount of antibodies or T cells is available to cause a noticeable reaction on reexposure to the antigen - CORRECT ANSWERS sensitized Delayed hypersensitivity reactions involve __ lymphocytes, but not __ lymphocytes - CORRECT ANSWERS T; B in antibody-dependent, cell mediated cytotoxicity, target cells die by _____ - CORRECT ANSWERS apoptosis Defective peripheral tolerance is a factor in development of _____ - CORRECT ANSWERS autoimmunity Individuals with type O blood are universal ____ because their RBCs have _____. - CORRECT ANSWERS donors; no A and B antigens Genetic predispostiion to autoimmunity often involves ____ alleles - CORRECT ANSWERS MHC
Graft-verus-host disease occurrs in graft recipients who are ______. - CORRECT ANSWERS immunocompromised Histamine released from mast cells causes signs and symptoms of inflammation by binding to ___ receptors. - CORRECT ANSWERS H Although type II hypersensitivity reactions can affect cells by several different mechanisms, they all involve antigens that are expressed in ____ tissues - CORRECT ANSWERS only specific Write the type of hypersensitivity: type I (IgE-mediated), type II (tissue-specific), type III (immune complex), type IV (cell-mediated) Child develops systemic anaphylaxis after eating peanut butter - CORRECT ANSWERS Type I (IgE) Write the type of hypersensitivity: type I (IgE-mediated), type II (tissue-specific), type III (immune complex), type IV (cell-mediated) Adult develops rejection of a transplanted heart - CORRECT ANSWERS Type IV (cell-mediated) Write the type of hypersensitivity: type I (IgE-mediated), type II (tissue-specific), type III (immune complex), type IV (cell-mediated) Adult develops rash on legs from poison icy after hiking in shorts - CORRECT ANSWERS Type IV (cell-mediated)
B. IgE attaches to mast cells G. Individual has additional allergen exposure F. IgE on mast cells binds allergen D. Mast cells degranulate H. Individual has clinical signs and symptoms of allergy Autoimmunity occurs when the immune system reacts against ____ to such a degree that autoantibodies or auto reactive T cells damage the person's own tissues - CORRECT ANSWERS self-antigens Hypersensitivity reactions require ______ against a particular antigen that results in primary and secondary immune responses - CORRECT ANSWERS sensitization Complement deficiencies often involve recurrent infections with encapsulated bacteria because C3b is an ______ - CORRECT ANSWERS opsonin Hypogammaglobulinemia is classified as a ____ lymphocyte deficiency. - CORRECT ANSWERS B Cells in intact immunologically privileged sites have cell surface ligands that cause entering lymphocytes to undergo _______ - CORRECT ANSWERS apoptosis DiGeorge syndrome involves deficient ____ lymphocyte immunity due to complete or partial lack of the ______ - CORRECT ANSWERS T; thymus Antibodies can ______ target cell receptors, as in Graves disease; antibodies also can destroy or ______ receptors as in myasthenia gravis - CORRECT ANSWERS activate; block
Unusual or recurrent severe infections are common indicators of immune _______ - CORRECT ANSWERS deficiency The technical terms for hives is _______ - CORRECT ANSWERS urticaria