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BIOL 1306 Lecture Notes Chapters
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Key Concepts or Important Topics:
CONCEPT 4.1: Organic chemistry is key to the origin of life
Figure 4. Can organic molecules form under conditions estimated to simulate those on the early Earth?
CONCEPT 4.2: Carbon atoms can form diverse molecules by bonding to four other atoms
Figure 4. The shapes of three simple organic molecules
Fig. 4-
Hydrogen (valence = 1)
Oxygen (valence = 2)
Nitrogen (valence = 3)
Carbon (valence = 4)
H O N C
The number of unpaired electrons in the valence shell of an atom is generally equal to its valence , the number of covalent bonds it can form
Figure 4. Four ways that carbon skeletons can vary
Figure 4.
Isomers are compounds with the same molecular formula but different structures and properties
— OH Hydroxyl Polar — CO Carbonyl Polar —COOH Carboxyl Polar (Acidic) —NH 2 Amino Polar (Basic) —SH Sulfhydryl Polar — PO 4 Phosphate Polar —CH 3 Methyl Non-polar
Propanal, an aldehyde Acetone, the simplest ketone Sugars with ketone groups are called ketoses; those with aldehydes are called aldoses. Compound name: Ketone or aldehyde
Carbonyl group ( C = O)
Figure 4.9aa
Ethanol, the alcohol present in alcoholic beverages Polar due to electronegative oxygen. Forms hydrogen bonds with water. Compound name: Alcohol
Hydroxyl group (—OH)
(may be written HO—)
Hydroxyl and Carbonyl Groups: Present in Sugars
Acetic acid, which gives vinegar its sour taste Acts as an acid. Compound name: Carboxylic acid, or organic acid
Carboxyl group (—COOH)
Ionized form of —COOH (carboxylate ion), found in cells
Glycine, an amino acid (note its carboxyl group)
Acts as a base. Compound name: Amine
Amino group (—NH 2 )
Ionized form of —NH 2 , found in cells
Carboxyl and Amino Groups are present in Amino Acids
Cysteine
Glycerol phosphate
Organic phosphate
Sulfhydryl group (—SH) Thiol
Phosphate group (—OPO 32 −)
Methyl group (—CH 3 ) Methylated compound 5-Methyl cytosine
Chemical Group Compound Name Examples
Sulfhydryl group is present in amino acid Cysteine Phosphate group is present in DNA, RNA & ATP Methyl group bound to DNA plays a role in gene expression
A B^ C
The general structure of amino acids are shown in this figure. What functional groups are highlighted in salmon and yellow, respectively?
a) Amino and carbonyl b) Hydroxyl and carbonyl c) Amino and carboxyl d) Methyl and carboxyl e) Methyl and hydroxyl
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