Cellular Functions and Pathologies, Exams of Advanced Education

A comprehensive overview of various cellular functions, including movement, conductivity, metabolic absorption, secretion, excretion, respiration, and reproduction. It delves into the structure and roles of key cellular organelles, such as the nucleus, ribosomes, endoplasmic reticulum, and plasma membrane. The document also explores different modes of cellular transport, including passive and active transport, as well as communication mechanisms between cells. Additionally, it covers common causes of cellular injury, such as hypoxia, chemical exposure, and physical trauma, and the resulting pathological processes, including necrosis, atrophy, hypertrophy, hyperplasia, and neoplasia. This detailed information on cellular biology and pathology would be highly valuable for students studying topics related to anatomy, physiology, pathology, or cell biology.

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2024/2025

Available from 09/23/2024

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UT TYLER FNP NURS 5350 Adv Patho
Exam 1 With 100% Correct Answers
2023
Seven specialized cellular functions: - Correct Answer-movement, conductivity,
metabolic absorption, secretion, excretion, respiration, and reproduction
Nucleus - Correct Answer-aids in cell division and control of genetic info, contains DNA
(think the egg yolk)
Ribosomes - Correct Answer-RNA-protein complexes; float freely in cytoplasm; provide
sites for cellular protein synthesis; packages and modifies protein for transportation and
secretion
Endoplasmic Reticulum (ER) - Correct Answer-specializes in the synthesis and
transport of the protein and lipid components of most of the cells organelles (memory
factory)
Golgi complex - Correct Answer-Organelle that packages and distributes proteins into
vesicles and transports within and outside of cell (refining plant in cytoplasm; traffic cop-
what goes in and out of cytoplasm)
Lysosomes - Correct Answer-An organelle containing digestive enzymes; digest and
remove wastes, digest debris from dead cells; if ruptured, they can digest cell contents;
autodigestion occurs in starvation
Mitochondria - Correct Answer-Powerhouse of the cell, organelle that is the site of ATP
(energy) production; pathway for metabolism of carbs, lipids, and amino acids into ATP;
to keep the cell alive; can grow and self-replicate in the cell
Cytoskeleton - Correct Answer-A network of fibers that holds the cell together, helps the
cell to keep its shape, and aids in movement; "bones and muscle" of the cell; have cilia
to move it on out
Characteristics of plasma membrane - Correct Answer-made up of lipids and proteins;
the basic component is a bi-layer of lipid molecules that are responsible for the
structural integrity of the membrane
The _______________ prevents water soluble molecules from entering cells across the
plasma membrane - Correct Answer-Phospholipid layer
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UT TYLER FNP NURS 5350 Adv Patho

Exam 1 With 100% Correct Answers

Seven specialized cellular functions: - Correct Answer-movement, conductivity, metabolic absorption, secretion, excretion, respiration, and reproduction Nucleus - Correct Answer-aids in cell division and control of genetic info, contains DNA (think the egg yolk) Ribosomes - Correct Answer-RNA-protein complexes; float freely in cytoplasm; provide sites for cellular protein synthesis; packages and modifies protein for transportation and secretion Endoplasmic Reticulum (ER) - Correct Answer-specializes in the synthesis and transport of the protein and lipid components of most of the cells organelles (memory factory) Golgi complex - Correct Answer-Organelle that packages and distributes proteins into vesicles and transports within and outside of cell (refining plant in cytoplasm; traffic cop- what goes in and out of cytoplasm) Lysosomes - Correct Answer-An organelle containing digestive enzymes; digest and remove wastes, digest debris from dead cells; if ruptured, they can digest cell contents; autodigestion occurs in starvation Mitochondria - Correct Answer-Powerhouse of the cell, organelle that is the site of ATP (energy) production; pathway for metabolism of carbs, lipids, and amino acids into ATP; to keep the cell alive; can grow and self-replicate in the cell Cytoskeleton - Correct Answer-A network of fibers that holds the cell together, helps the cell to keep its shape, and aids in movement; "bones and muscle" of the cell; have cilia to move it on out Characteristics of plasma membrane - Correct Answer-made up of lipids and proteins; the basic component is a bi-layer of lipid molecules that are responsible for the structural integrity of the membrane The _______________ prevents water soluble molecules from entering cells across the plasma membrane - Correct Answer-Phospholipid layer

Prokaryote - Correct Answer-unicellular organism lacking a nucleus; contains NO organelles (include cyanobacteria, bacteria, and rickettsia) Eukaryote - Correct Answer-organism whose cells contain a nucleus; "good nucleus;" larger w/ intracellular anatomy cellular receptors - Correct Answer-protein molecules on the plasma membrane, in the cytoplasm, or in the nucleus that can recognize and bind with specific smaller molecules called ligands 3 types of cellular receptors - Correct Answer-plasma membrane receptors, channel- linked receptors, non-channel-linked receptors passive transport - Correct Answer-The movement of materials through a cell membrane WITHOUT using energy; no-energy transport of uncharged molecules through any semi-permeable barrier (occurs down a concentration gradient) Diffusion - Correct Answer-Movement of molecules from an area of higher concentration to an area of lower concentration. concentration gradient - Correct Answer-A difference in the concentration of a substance across a distance. hydrostatic pressure - Correct Answer-the mechanical force of water PUSHING against cellular membranes Osmosis - Correct Answer-Diffusion of water through a selectively permeable membrane; from a region of higher water concentration to a region of lower water concentration; directly r/t hydrostatic pressure and solute concentration; PULL active transport - Correct Answer-the movement of materials through a cell membrane using energy mediated transport - Correct Answer-simultaneous movement of a single solute molecule in one direction (uniport); of two different solute molecules in one direction (symport); of two different solute molecules in opposite directions (antiport) passive mediated transport - Correct Answer-"facilitated diffusion;" moving molecules through membranes WITHOUT expending energy; moving DOWN a concentration gradient active mediated transport - Correct Answer-"active transport;" Requires the expenditure of metabolic energy (ATP); moving UP or AGAINST a concentration gradient; the major cellular energy currency

What is the most common cause of cellular injury? - Correct Answer-hypoxia (lack of oxygen) What is the most common cause of hypoxia? - Correct Answer-ischemia (reduced blood supply) chemical injury to cells - Correct Answer-begins w/ a biochemical interaction between a toxic substance and the cell's plasma membrane (which is ultimately damaged)--

leading to increased permeability examples of chemical injury - Correct Answer-carbon tetrachloride (CC14) converts into a free radical; chemical poisoning including lead, carbon monoxide, and ethanol Physical Injury of Cell - Correct Answer-direct trauma from external force; inflammatory response ionizing radiation - Correct Answer-x-rays, gamma rays, alpha and beta rays, and sunlight lead to damaged DNA; cells that rapidly divide are most sensitive; example cells are fetus, germ cells, tumor cells, GI mucosa and bone; effects may be immediate or delayed depending on dose and duration of exposure Hypothermic injury - Correct Answer-frostbite; initial vasoconstriction w/ paralysis of vasomotor control leading to vasodilation-->increased membrane permeability-->cellular swelling-->increased blood viscosity-->ischemic injury; thrombosis can also occur leading to gangrene Hyperthermic injury - Correct Answer-burn; tissues destroyed; injury depends upon extent of injury and how many skin layers are involved partial thickness injuries - Correct Answer-capillary dilation and increased loss of protein-rich fluid (redness, swelling, and blistering) full thickness injuries - Correct Answer-extensive loss of fluid and plasma proteins; cellular regeneration is not possible so grafting is needed to protect and heal 5 types of necrosis - Correct Answer-coagulative, liquefactive, caseous, fat necrosis, gangrenous Coagulative necrosis - Correct Answer-cell proteins are altered or denatured; caused from hypoxia caused by severe ischemia Where does coagulative necrosis primarily occur? - Correct Answer-heart, kidneys, and adrenal gland

liquefactive necrosis - Correct Answer-results from ischemic injury to neurons and glial cells in the brain; also the process involved in abscess formation; self-digestion leads to liquid which is encapsulated in cyst and abscesses caseous necrosis - Correct Answer-degeneration and death of tissue with a cheese-like appearance; TB what type of necrosis is the combination of coagulative and liquefactive necrosis? - Correct Answer-caseous necrosis where does fat necrosis occur? - Correct Answer-breast, pancreas, and other abdominal organs fat necrosis - Correct Answer-caused by lipase; lipases break down triglycerides, releaseing free fatty acids which then combine w/ Ca, Mg, and Na, creating soaps; the necrotic tissue appears opaque and chalk white Gangrenous necrosis - Correct Answer-death of tissue from severe hypoxic injury dry gangrene - Correct Answer-result of coagulative necrosis; dry, brown or black wet gangrene - Correct Answer-develops when neutrophils invade the site, causing liquefactive necrosis; site is cold, swollen, and black w/ foul odor gas gangrene - Correct Answer-due to infection by clostridium (anaerobic bacteria); can lead to death if enzymes lyse the membrane of RBCs destroying their oxygen carrying capacity atrophy - Correct Answer-reduction (shrinking) in cell size causes of atrophy - Correct Answer-disuse (muscle tissue), reduction in blood supply (arteriosclerotic changes causing reduced blood supply to the brain), and decreased hormonal stimulation (aging gonads, enlarged mammary) hypertrophy - Correct Answer-increase in cell size d/t increased workload (muscle); leads to greater metabolic demand and energy needs hyperplasia - Correct Answer-increase in number of cells d/t an increase in cell division (ex. BPH) compensatory cell growth - Correct Answer-response to an injury that is prolonged enough to stimulate production of growth factors (ex callus) hormonal hyperplasia - Correct Answer-usually in estrogen-dependent organs (breast and uterus); ex. monthly hyperplasia of endometrium