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Cholinergic Agonists: Pharmacology and Clinical Uses, Exams of Nursing

Chamberlain College of NursingNursing

A chapter on cholinergic agonists, which are drugs that increase the activity of acetylcholine receptor sites throughout the body. It includes questions and answers on the dosing schedule of cevimeline, the function of cholinergic agonists, adverse effects of bethanechol, and the use of cholinergic agonists in diagnosing myasthenia gravis and treating alzheimer's disease. It also discusses the toxic effects of anticholinesterase drugs and the drug of choice for cholinergic toxicity.

Typology: Exams

2023/2024

Available from 03/02/2024

lennyjast
lennyjast 🇺🇸

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Chapter 32- Cholinergic Agonists
1. Your patient has had cevimeline (Evoxac) prescribed. What would be an
appropriate dosing schedule for a patient taking cevimeline (Evoxac)?
A) Once a day
B) Twice a day
C) Three times a day
D) Every four hours
2. A student asks the pharmacology instructor to describe the function of a
cholinergic agonist. What would the instructor reply?
A) Cholinergic agonists increase the activity of dopamine receptor sites throughout
the brain and spinal cord.
B) Cholinergic agonists decrease the activity of GABA receptor sites throughout
the body.
C) Cholinergic agonists increase the activity of acetylcholine receptor sites
throughout the body.
D) Cholinergic agonists decrease the activity of norepinephrine receptor
sites throughout the brain and spinal cord.
3. A 10-year-old child with spina bifida is receiving bethanechol (Urecholine) for
treatment of neurogenic bladder. What adverse effect will the nurse be sure to
assess for?
A) Constipation
B) Loss of bowel and bladder control
C) Decrease salivation
D) Increased appetite
4. A nurse is writing a plan of care for a patient who is taking bethanechol
(Urecholine). What would be an appropriate outcome for this patient?
A) Pupillary dilation
B) Increased blood pressure
C) Improved bladder function
D) Decreased secretions
5. Which of the following drugs would be used to diagnose myasthenia gravis in a child?
A) Atropine (Generic)
B) Bethanechol (Urecholine)
C) Edrophonium (Tensilon)
D) Neostigmine (Prostigmine)
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Chapter 32- Cholinergic Agonists

  1. Your patient has had cevimeline (Evoxac) prescribed. What would be an appropriate dosing schedule for a patient taking cevimeline (Evoxac)? A) Once a day B) Twice a day C) Three times a day D) Every four hours
  2. A student asks the pharmacology instructor to describe the function of a cholinergic agonist. What would the instructor reply? A) Cholinergic agonists increase the activity of dopamine receptor sites throughout the brain and spinal cord. B) Cholinergic agonists decrease the activity of GABA receptor sites throughout the body. C) Cholinergic agonists increase the activity of acetylcholine receptor sites throughout the body. D) Cholinergic agonists decrease the activity of norepinephrine receptor sites throughout the brain and spinal cord.
  3. A 10-year-old child with spina bifida is receiving bethanechol (Urecholine) for treatment of neurogenic bladder. What adverse effect will the nurse be sure to assess for? A) Constipation B) Loss of bowel and bladder control C) Decrease salivation D) Increased appetite
  4. A nurse is writing a plan of care for a patient who is taking bethanechol (Urecholine). What would be an appropriate outcome for this patient? A) Pupillary dilation B) Increased blood pressure C) Improved bladder function D) Decreased secretions
  5. Which of the following drugs would be used to diagnose myasthenia gravis in a child? A) Atropine (Generic) B) Bethanechol (Urecholine) C) Edrophonium (Tensilon) D) Neostigmine (Prostigmine)
  1. A patient is brought to the Emergency Department having a cholinergic reaction, which includes a severe drop in blood pressure. What drug will you expect to administer? A) Atropine (Generic) B) Edrophonium (Tensilon) C) Propranolol (Inderal) D) Succinylcholine (Anectine)
  2. Memantine hydrochloride (Namenda) has been prescribed for a 63-year-old patient who has a confirmed diagnosis of Alzheimer's disease. What would be the target dose for this patient? A) 5 mg/d B) 10 mg b.i.d. C) 15 mg/d D) 20 mg b.i.d.
  3. An Alzheimer's patient taking donepezil (Aricept) has a complete blood count that indicates they are anemic. What drug taken by the patient could be the cause of the anemia? A) Cimetidine (Tagamet) B) Ibuprofen (Advil) C) Diltiazem (Cardizem) D) Furosemide (Lasix)
  4. Military personnel who have been exposed to particular nerve gases have what drug approved to treat them? A) Neostigmine (Prostigmine) B) Pyridostigmine (Mestinon) C) Ambenonium (Mytelase) D) Endrophonium (Tensilon)
  5. A patient with postoperative abdominal distention is given neostigmine (Prostigmine) for abdominal distention. What outcome will the nurse assess for? A) Absence of flatus through the rectum B) Increased urination C) Presence of bowel sounds D) Absence of bowel movements
  1. What condition is the cholinergic drug bethanechol (Duvoid) used to treat? A) Hypertension B) Urinary retention C) Bradycardia D) Asthma
  2. The nurse is caring for a patient who has anticholinesterase drugs prescribed. When administering anticholinesterase drugs, the nurse should assess the patient for toxic effects of the drugs. What do these include? A) Paralytic ileus B) Abdominal distension C) Hypertension D) Muscle weakness
  3. Which indirect-acting anticholinesterase medication is recommended as an antidote to neuromuscular junction blockers. A) Pyridostigmine (Mestinon) B) Donespezil (Aricept) C) Rivastigmine (Exelon) D) Ambenonium (Mytelase)
  4. A patient is brought to the Emergency Department after a motor vehicle accident. The patient is diagnosed with multiple injuries including a bladder injury. The patient is taken to surgery and develops a nonobstructive postoperative urinary retention. What drug would the nurse expect to be ordered for this patient? A) Neostigmine B) Bethanechol C) Ambenonium D) Pyridostigmine
  5. A patient is taking memantine for Alzheimer's disease. This drug does not affect what? A) Antiadrenergic receptor sites B) Glucagon receptor sites C) GABA receptor sites D) Antihistamine receptor sites
  1. A patient is brought to the Emergency Department (ED) and is found to have cholinergic toxicity. What is the drug of choice to treat this condition? A) Atropine B) Epinepherine C) Lidocaine D) Tensilon
  2. A 47-year-old male is suspected of having been exposed to nerve gas. Atropine is given to temporarily block cholinergic activity and to activate acetylcholine sites in the central nervous system. What drug is given with the atropine to free up the acetylcholinesterase to start breaking down acetylcholine? A) Pyridostigmine B) Pralidoxime C) Neostigmine D) Rivastigmine
  3. A 77-year-old male is brought to the Emergency Department with a cholinergic overdose. The nurse knows that older adults are likely to have a greater number of adverse drug effects because why? A) Age-related pathologic events B) Concurrent physiologic events C) Age-related physiologic changes D) Superimposed physiologic events
  4. You are caring for a 45-year-old female patient who is in chronic renal failure. What cholinergic drug is contraindicated for this patient? A) Neostigmine B) Pyridostigmine C) Edrophonium D) Galantamine
  1. You are a critical care nurse working in the ICU. You know that cholinergic drugs have very specific uses in critical illness. What is a use for pyridostigmine in critical care? A) Reverse neuromuscular junction blockers B) Reverse smooth muscle blockade C) Reverse cholinergic crisis D) Reverse myasthinic crisis
  2. A patient diagnosed with myasthenia gravis is having trouble swallowing. What anticholinesterase inhibitor would be the drug of choice for this patient because it can be given parenterally? A) Galantamine B) Pyridostigmine C) Neostigmine D) Bethanechol

Answer Key

1. C

2. C

3. B

4. C

5. C

6. A

7. B

8. B

9. B

10. C

11. B

12. C

13. A

14. B

15. A

16. B

17. D

18. A

19. B

20. C

21. A

22. B

23. C

24. D

25. A

26. B

27. C

28. C

29. A

30. B