Chapter 32- Cholinergic Agonists, Exams of Nursing

Your patient has had cevimeline (Evoxac) prescribed. What would be an appropriate dosing schedule for a patient taking cevimeline (Evoxac)? Once a day Twice a day Three times a day Every four hours A student asks the pharmacology instructor to describe the function of a cholinergic agonist. What would the instructor reply? Cholinergic agonists increase the activity of dopamine receptor sites throughout the brain and spinal cord. Cholinergic agonists decrease the activity of GABA receptor sites throughout the body. Cholinergic agonists increase the activity of acetylcholine receptor sites throughout the body. Cholinergic agonists decrease the activity of norepinephrine receptor sites throughout the brain and spinal cord.

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Chapter 32- Cholinergic Agonists
Your patient has had cevimeline (Evoxac) prescribed. What would be an
appropriate dosing schedule for a patient taking cevimeline (Evoxac)?
Once a day
Twice a day
Three times a day
Every four hours
A student asks the pharmacology instructor to describe the function of a
cholinergic agonist. What would the instructor reply?
Cholinergic agonists increase the activity of dopamine receptor sites throughout
the brain and spinal cord.
Cholinergic agonists decrease the activity of GABA receptor sites throughout
the body.
Cholinergic agonists increase the activity of acetylcholine receptor sites
throughout the body.
Cholinergic agonists decrease the activity of norepinephrine receptor
sites throughout the brain and spinal cord.
A 10-year-old child with spina bifida is receiving bethanechol (Urecholine) for
treatment of neurogenic bladder. What adverse effect will the nurse be sure to
assess for?
Constipation
Loss of bowel and bladder control
Decrease salivation
Increased appetite
A nurse is writing a plan of care for a patient who is taking bethanechol
(Urecholine). What would be an appropriate outcome for this patient?
Pupillary dilation
Increased blood pressure
Improved bladder function
Decreased secretions
Which of the following drugs would be used to diagnose myasthenia gravis in a child?
Atropine (Generic)
Bethanechol (Urecholine)
Edrophonium (Tensilon)
Neostigmine (Prostigmine)
A patient is brought to the Emergency Department having a cholinergic reaction,
which includes a severe drop in blood pressure. What drug will you expect to
administer?
Atropine (Generic)
Edrophonium (Tensilon)
Propranolol (Inderal)
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Chapter 32- Cholinergic Agonists

  • Your patient has had cevimeline (Evoxac) prescribed. What would be an appropriate dosing schedule for a patient taking cevimeline (Evoxac)?
    • Once a day
    • Twice a day
    • Three times a day
    • Every four hours
  • A student asks the pharmacology instructor to describe the function of a cholinergic agonist. What would the instructor reply?
    • Cholinergic agonists increase the activity of dopamine receptor sites throughout the brain and spinal cord.
    • Cholinergic agonists decrease the activity of GABA receptor sites throughout the body.
    • Cholinergic agonists increase the activity of acetylcholine receptor sites throughout the body.
    • Cholinergic agonists decrease the activity of norepinephrine receptor sites throughout the brain and spinal cord.
  • A 10-year-old child with spina bifida is receiving bethanechol (Urecholine) for treatment of neurogenic bladder. What adverse effect will the nurse be sure to assess for?
    • Constipation
    • Loss of bowel and bladder control
    • Decrease salivation
    • Increased appetite
  • A nurse is writing a plan of care for a patient who is taking bethanechol (Urecholine). What would be an appropriate outcome for this patient?
    • Pupillary dilation
    • Increased blood pressure
    • Improved bladder function
    • Decreased secretions
  • Which of the following drugs would be used to diagnose myasthenia gravis in a child?
    • Atropine (Generic)
    • Bethanechol (Urecholine)
    • Edrophonium (Tensilon)
    • Neostigmine (Prostigmine)
  • A patient is brought to the Emergency Department having a cholinergic reaction, which includes a severe drop in blood pressure. What drug will you expect to administer?
    • Atropine (Generic)
    • Edrophonium (Tensilon)
    • Propranolol (Inderal)
  • Succinylcholine (Anectine)
  • Memantine hydrochloride (Namenda) has been prescribed for a 63-year-old patient who has a confirmed diagnosis of Alzheimer's disease. What would be the target dose for this patient?
  • 5 mg/d
  • 10 mg b.i.d.
  • 15 mg/d
  • 20 mg b.i.d.
  • An Alzheimer's patient taking donepezil (Aricept) has a complete blood count that indicates they are anemic. What drug taken by the patient could be the cause of the anemia?
  • Cimetidine (Tagamet)
  • Ibuprofen (Advil)
  • Diltiazem (Cardizem)
  • Furosemide (Lasix)
  • Military personnel who have been exposed to particular nerve gases have what drug approved to treat them?
  • Neostigmine (Prostigmine)
  • Pyridostigmine (Mestinon)
  • Ambenonium (Mytelase)
  • Endrophonium (Tensilon)
  • A patient with postoperative abdominal distention is given neostigmine (Prostigmine) for abdominal distention. What outcome will the nurse assess for?
  • Absence of flatus through the rectum
  • Increased urination
  • Presence of bowel sounds
  • Absence of bowel movements
  • You are caring for a 49-year-old patient, who has been receiving bethanechol (Duvoid) for 1 week. Your patient develops progressive muscle weakness and respiratory difficulty. What would you suspect is happening with your patient?
  • Myasthenic crisis
  • Cholinergic overdose
  • Anaphylactic reaction
  • Pulmonary edema
  • A 70-year-old female patient has just been diagnosed with Alzheimer's disease. What cholinergic drug is used for the treatment of Alzheimer's disease?
  • Bethanechol (Duvoid)
  • Neostigmine (Prostigmine)
  • Donepezil (Aricept)
  • Endrophonium (Tensilon)

patient is taken to surgery and develops a nonobstructive postoperative urinary retention. What drug would the nurse expect to be ordered for this patient?

  • Neostigmine
  • Bethanechol
  • Ambenonium
  • Pyridostigmine
  • A patient is taking memantine for Alzheimer's disease. This drug does not affect what?
  • Antiadrenergic receptor sites
  • Glucagon receptor sites
  • GABA receptor sites
  • Antihistamine receptor sites
  • A patient is brought to the Emergency Department (ED) and is found to have cholinergic toxicity. What is the drug of choice to treat this condition?
  • Atropine
  • Epinepherine
  • Lidocaine
  • Tensilon
  • A 47-year-old male is suspected of having been exposed to nerve gas. Atropine is given to temporarily block cholinergic activity and to activate acetylcholine sites in the central nervous system. What drug is given with the atropine to free up the acetylcholinesterase to start breaking down acetylcholine?
  • Pyridostigmine
  • Pralidoxime
  • Neostigmine
  • Rivastigmine
  • A 77-year-old male is brought to the Emergency Department with a cholinergic overdose. The nurse knows that older adults are likely to have a greater number of adverse drug effects because why?
  • Age-related pathologic events
  • Concurrent physiologic events
  • Age-related physiologic changes
  • Superimposed physiologic events
  • You are caring for a 45-year-old female patient who is in chronic renal failure. What cholinergic drug is contraindicated for this patient?
  • Neostigmine
  • Pyridostigmine
  • Edrophonium
  • Galantamine
  • A 72-year-old male is newly diagnosed with Alzheimer's disease. The patient's daughter asks you how her father's medication is going to help him. What would be the nurse's best response?
  • “The drugs work by increasing ACh levels in the brain and slowing the progression of the disease.”
  • “The drugs work by crossing the blood-brain barrier and decreasing ACh levels in the brain.”
  • “The drugs work by decreasing ACh levels in the brain and slowing the progression of the disease.”
  • “The drugs work by crossing the blood-brain barrier and decreasing ACh levels in the neuromuscular junctions.”
  • A patient has been newly diagnosed with myasthenia gravis. What is important advice for the family?
  • If one dose of medication is missed double the next dose
  • Have one or more family members learn the warning signs of drug overdose
  • Teach family how to help patient walk with cane
  • Teach the patient how to do CPR
  • A new patient has come to the clinic. The patient tells the nurse they take Aricept. Why would it be important for the nurse to assess the patient's medical and medication history?
  • Because of the many bodily functions affected by the cholinergic medications' ability to stimulate the autonomic nervous system
  • Because of the many bodily functions affected by the anti-cholinergic medications' ability to stimulate the parasympathetic nervous system
  • Because of the many bodily functions affected by the cholinergic medications' ability to stimulate the parasympathetic nervous system
  • Because of the many bodily functions affected by the cholinergic medications' ability to stimulate the sympathetic nervous system
  • What family of drugs is used in the treatment of myasthenia gravis?
  • Cholinesterase agents
  • Irreversible inhibitors
  • Anti-cholinesterase agents
  • Irreversible agonists
  • You are a critical care nurse working in the ICU. You know that cholinergic drugs have very specific uses in critical illness. What is a use for pyridostigmine in critical care?
  • Reverse neuromuscular junction blockers
  • Reverse smooth muscle blockade
  • Reverse cholinergic crisis
  • Reverse myasthinic crisis
  • A patient diagnosed with myasthenia gravis is having trouble swallowing. What anticholinesterase inhibitor would be the drug of choice for this patient because it can be given parenterally?
  • Galantamine
  • Pyridostigmine
  • Neostigmine
  • Bethanechol

Answer Key