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CHAPTER-8_URINARY SYSTEM CHAPTER-8_URINARY SYSTEM
Typology: Summaries
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Components: Kidneys (2) – retroperitoneal, T12–L3 level; right lower than left. Ureters (2) – carry urine to bladder. Urinary bladder – stores urine. Urethra – excretes urine. Functions: Excretion of metabolic wastes (urea, creatinine, uric acid). Regulation of water, electrolytes, and pH. Endocrine functions: Renin (BP control) , Erythropoietin (RBC production) , Vitamin D activation. Microscopic unit: Nephron — glomerulus + tubules; filters ~180 L/day. 🩻 2. IMAGING MODALITIES AND THEIR ROLES Modality Role / Findings Radiography (KUB) Demonstrates calcifications, renal size, position. Intravenous urography (IVU/IVP) Shows collecting system anatomy and function (now less common). Sonography First-line for hydronephrosis, cysts, masses, bladder volume, obstruction; no radiation. CT (with/without contrast) Gold standard for renal/ureteric stones, trauma, staging of tumors. MRI Characterizes masses, evaluates renal veins and IVC involvement; MR urography for function. Nuclear Medicine (DMSA, MAG- scans) Renal perfusion and differential function.
Modality Role / Findings Voiding Cystourethrogram (VCUG) Used for vesicoureteral reflux and pediatric infections. CAMRT note: → Sonography = functional & structural. → CT = stones & tumors. → VCUG = reflux. 🩻 3. CONGENITAL ANOMALIES Anomaly Description & Imaging Appearance Clinical Significance Renal agenesis (unilateral/bilateral) Absence of one or both kidneys. Bilateral incompatible with life; unilateral asymptomatic. Supernumerary kidney Extra small kidney with separate pelvis & ureter. Usually non-functioning. Hypoplasia Small but normal-functioning kidney. Often incidental. Fusion anomalies (horseshoe kidney) Lower poles fused across midline; kidneys lie lower with anterior ureters. Increased infection or calculus risk. Crossed ectopia Both kidneys on one side; one ureter crosses midline. May cause mass effect or obstruction. Malrotation Hilum rotated anteriorly or posteriorly. May distort collecting system on IVU. Duplicated collecting system Two pelvicalyceal systems ± two ureters. Prone to reflux and infection. Ureterocele Cystic dilatation of distal ureter in bladder wall. “Cobra-head” sign on IVU; causes obstruction. Polycystic kidney disease Numerous cysts; autosomal Enlarged kidneys, renal
Pathology Key Points Imaging Appearance Hydronephrosis Dilation of renal pelvis & calyces from obstruction (stone, stricture, mass). US: fluid-filled dilatation; CT: pelvicalyceal distension. Posterior urethral valves Congenital membranous obstruction in male infants. VCUG: dilated posterior urethra; reflux; bilateral hydronephrosis. Vesicoureteral reflux Retrograde urine flow during voiding. VCUG: reflux seen from bladder to ureters. CAMRT exam note: Remember obstruction = dilatation proximal to lesion. CT non-contrast is preferred for renal colic. 🩻 6. NEOPLASTIC CONDITIONS Pathology Nature / Origin Imaging Features & Notes Renal cell carcinoma (hypernephroma) Most common adult kidney malignancy (arises from tubular epithelium). CT: solid, irregular, enhances with contrast, may invade renal vein/IVC. May cause hematuria or flank pain. Wilms tumor (nephroblastoma) Common pediatric malignancy (<5 years). Large soft-tissue abdominal mass displacing bowel; CT for extent. Transitional cell carcinoma Arises from renal pelvis, ureter, or bladder urothelium. Filling defect in collecting system on IVU; CT urography now standard. Metastases From lung, breast, melanoma. Multiple small hypoattenuating lesions on CT. Bladder carcinoma Strongly linked to smoking & chemicals. Irregular mass or wall thickening; CT for staging. CAMRT Remember: RCC = solid, vascular, parenchymal mass. TCC = filling defect in collecting system.
Condition Mechanism / Pathophysiology Clinical & Imaging Features Renal failure (acute/chronic) Acute : obstruction, ischemia, or toxins. Chronic : progressive nephron loss (diabetes, HTN). US: small echogenic kidneys in chronic; large in acute. Labs: ↑BUN, creatinine. Nephrocalcinosis Calcium deposition in renal parenchyma (hyperparathyroidism). CT: cortical or medullary calcification pattern. Papillary necrosis Necrosis of renal papillae (diabetes, analgesic abuse). IVU/CT: “ball-on-tee” or sloughed papilla. Polycystic kidney disease Genetic cystic enlargement replacing parenchyma. US: multiple cysts; CT: “Swiss cheese” appearance. Hypertension (renovascular) Atherosclerosis or fibromuscular dysplasia → ↓renal perfusion → renin- angiotensin activation. NM scan or MR angiography shows asymmetric perfusion. 8. RADIOGRAPHIC SIGNS & CAMRT PEARLS Sign / Description Seen In “Cobra-head sign” Ureterocele on IVU. “Putty kidney” Chronic renal TB (calcified shrunken kidney). “Ball-on-tee” sign Papillary necrosis. “Swiss-cheese” kidney Polycystic kidney disease. “Rim sign” Calcified renal cyst wall on CT.