Clinical Medicine HEENT Study Guide, Study Guides, Projects, Research of Clinical Medicine

Red Eye Clinical Medicine Topic Chart

Typology: Study Guides, Projects, Research

2020/2021

Uploaded on 06/03/2026

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Disease
Cause
Pathophys
Symptoms
Diagnosis
Treatment
Pictures
Notes
Hordeolum
(Stye)
(usually
S. aureus)
Poor eye or hand hygiene
& eye rubbing
Increased risk if underlying
skin condition
Sharing contaminated
makeup
Blockage/inf lammation/infect ion of
Meibomian gla nd or Zeiss or Moll gland
External
is localized, red,
swollen, acutely tender area
on the upper or lower lid
Internalis a meibomian gland
abscess that usually points
onto the conjunctival surface
of the lid
Clinical
Most resolv e spontaneously
Warm compresses (15 min,
4x/day)
Abx ointment (bacitr acin or
erythromycin)
I&D may be indic ated
**DO NOT
rub or
squeeze
Chalazion May follow an internal
hordeolum
Chronic blockage/ granulomatous
inflammation of a me ibomian gland
Hard, nontender swelling on
the upper or lower lid with
redness and swelling of
adjacent conjunctiva
Clinical Often resolves
spontaneously
Promote drainage by using
warm compresses
Incision and c urettage or
corticosteroid injection may
be effective
Posterior
Blepharitis
Long-term inflammation >
gland dysfunction and
fibrosis > damage to the
eyelid and ocular surface
More common in adults
and prevalence increases
with age
Chronic inflammation of the lid
secondary to dysf unction of the
Meibomian glands. Leads to instability
of the tear film. Promotes bacterial
growth (coag
-
neg staph,
corynebacterium sp, cutibacterium
acnes)
Usually bilateral
Red, swollen, or itchy eyelids
Gritty or burning sensation
Excessive tearing
Crusting or matting of
eyelashes
Flaking or scaling of the
eyelid skin
Blurred vision improved with
blinking
Trichiasis,
Entropion/Ectropion
Dry eye disease(frequent
complication)
Mostly clin ical
Slit lamp exam
allows detailed
exam of
Meibomian
glands and for
dry eye
Eyelid hygiene (mainstay)-
warm compresses, lid
massage, lid washing,
artificial tears
Bacterial-an tibiotic oint
(bacitracin, erythromycin,
azithromycin)
Demodex
-
oral ivermectin or
topical tea tree oil scrub
Anterior
Blepharitis
Staphylococcal Type
Fibrinous scales and
crust around
eyelashes; may alter
meibomian gland
secretion
Seborrheic Type
Dandruff-like skin
changes and greasy
scales around base of
eyelids/lashes
Demodex foliculorum
Cylindrical dandruff
or "sleeves"
Chronic inflammation of the lid margins
Same as posterior
Same as
posterior
Same as posterior
Bacterial
Conjunctivitis
S. aureus most common in
adults
Pseudomonas more
common in contact lens
wearers
More common in children
than adults
Acute onset
Often unilateral
Injection (diffuse)
Constant
purulent/m ucopurulent
discharge
Matted eyelids
Mild discomfort
Clinical
Cultures for
severe,
resistant, or
recurrent cases
Staining to
assess for
keratitis or
corneal defect
Usually self-limited, (10-14
days)
Handwash ing, sepa rate
towels
Abx eye gtts- Erythr omycin
oint, tobramycin,
trimethoprim
-
polymyxin B;
Ciprofloxacin gtts in contact
lens wearers
Gonorrhea
Conjunctivitis
Neisseria gonorrhoeae
Large amount of purulent
discharge
Injection
Chemosis
Lid swelling
Preauricular adenopathy
Urethritis
Tenderness to palpation
Culture
Gram stain
Refer to ophtha lmologist
Ceftriaxone and topical
bacitracin ointment
Sometime s
azithromycin/doxycycline
for possible chlamydia co-
infection
May require hospitalizatio n
for system ic and topical
therapy and for monitoring-
Keratitis and perfo ration can
occur
Viral
Conjunctivitis
Adenovirus (many
serotypes)
May start unilateral but then
progress to bilateral
Watery discharge
Conjunctival redness
Crusting in the mornings
Gritty sensatio n
URI symptoms common
Clinical
Self
-
limited
; Can last up to 2
wks
Cool compresses
Allergic
Conjunctivitis
Airborne allergens
(ex.
pollen)
Airborne allergens con tact eye > IgE
response > local mast cell
Bilateral
Itching, burning, gritty
Clinical
Antihistamine/Vaso constrict
or
Red Eye
Tuesday, A pril 4, 202 3 8:00 AM
Red Eye Page 1
staph
EY.int
train
sit
Mitient
Crusted watery
digited ita URI
gritty
pf2

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Disease Cause Pathophys Symptoms Diagnosis Treatment Pictures Notes Hordeolum (Stye) Staphylococcus sp (usually S. aureus)

Poor eye or hand hygiene & eye rubbing

Increased risk if underlying skin condition

Sharing contaminated makeup

Blockage/inflammation/infection of Meibomian gland or Zeiss or Moll gland External is localized, red, swollen, acutely tender area on the upper or lower lid

Internal is a meibomian gland abscess that usually points onto the conjunctival surface of the lid

Clinical • Most resolve spontaneously Warm compresses (15 min, 4x/day)

Abx ointment (bacitracin or erythromycin)

  • I&D may be indicated

**DO NOT

rub or squeeze Chalazion May follow an internal hordeolum Chronic blockage/ granulomatous inflammation of a meibomian gland Hard, nontender swelling on the upper or lower lid with redness and swelling of adjacent conjunctiva Clinical Often resolves spontaneously

Promote drainage by using warm compresses

Incision and curettage or corticosteroid injection may be effective

Posterior Blepharitis Long-term inflammation > gland dysfunction and fibrosis > damage to the eyelid and ocular surface More common in adults and prevalence increases with age Chronic inflammation of the lid secondary to dysfunction of the Meibomian glands. Leads to instability of the tear film. Promotes bacterial growth (coag-neg staph, corynebacterium sp, cutibacterium acnes)

  • Usually bilateral
  • Red, swollen, or itchy eyelids
  • Gritty or burning sensation
  • Excessive tearing Crusting or matting of eyelashes

Flaking or scaling of the eyelid skin

Blurred vision improved with blinking

Trichiasis, Entropion/Ectropion

Dry eye disease (frequent complication)

  • Mostly clinical Slit lamp exam allows detailed exam of Meibomian glands and for dry eye

Eyelid hygiene (mainstay)- warm compresses, lid massage, lid washing, artificial tears

Bacterial-antibiotic oint (bacitracin, erythromycin, azithromycin)

Demodex-oral ivermectin or topical tea tree oil scrub

Anterior Blepharitis Staphylococcal Type Fibrinous scales and crust around eyelashes; may alter meibomian gland secretion

Seborrheic Type Dandruff-like skin changes and greasy scales around base of eyelids/lashes

Demodex foliculorum Cylindrical dandruff or "sleeves"

Chronic inflammation of the lid margins Same as posterior Same as posterior Same as posterior Bacterial Conjunctivitis S. aureus most common in adults

Pseudomonas more common in contact lens wearers

More common in children than adults

  • Acute onset
  • Often unilateral
  • Injection (diffuse) Constant purulent/mucopurulent discharge
  • Matted eyelids
  • Mild discomfort
    • Clinical Cultures for severe, resistant, or recurrent cases

Staining to assess for keratitis or corneal defect

Usually self-limited, (10- days)

Handwashing, separate towels

Abx eye gtts- Erythromycin oint, tobramycin, trimethoprim-polymyxin B; Ciprofloxacin gtts in contact lens wearers

Gonorrhea Conjunctivitis Neisseria gonorrhoeae Large amount of purulent discharge

  • Injection
  • Chemosis
  • Lid swelling
  • Preauricular adenopathy
  • Urethritis
  • Tenderness to palpation
    • Culture
    • Gram stain
      • Refer to ophthalmologist Ceftriaxone and topical bacitracin ointment

Sometimes azithromycin/doxycycline for possible chlamydia co- infection

May require hospitalization for systemic and topical therapy and for monitoring- Keratitis and perforation can occur

Viral Conjunctivitis Adenovirus (many serotypes) May start unilateral but then progress to bilateral

  • Watery discharge
  • Conjunctival redness
  • Crusting in the mornings
  • Gritty sensation
  • URI symptoms common Clinical Self-limited; Can last up to 2 wks
  • Cool compresses Allergic Conjunctivitis Airborne allergens (ex. pollen) Airborne allergens contact eye > IgE response > local mast cell
  • Bilateral
  • Itching, burning, gritty
  • Clinical Antihistamine/Vasoconstrict or

Red Eye

Tuesday, April 4, 2023 8:00 AM Red Eye Page 1

staph

EY.int

train

sit

Mitient

Crusted

watery

digited

ita URI

gritty

Conjunctivitis pollen) response > local mast cell degranulation and release of chemical mediators (histamine, etc.) Itching, burning, gritty sensation, redness, watering

  • Chemosis Cobblestone papillae on the upper palpebral conjunctiva

or (naphazoline/pheniramine) Antihistamine with mast cell stabilizing properties (olopatadine-Pataday)

Mast cell stabilizers (cromolyn-Opticrom)

  • Topical NSAIDs
  • Glucocorticoids Keratoconjuncti vitis Sicca (dry eye) Systemic drugs (antihistamines, anticholinerigcs, some psychotropic meds)

Systemic illness (Sarcoidosis, Sjogren’s Syndrome)

Hormonal changes (primarily d/t decreased androgens)

Radiation therapy (if includes the orbit)

CN V or VII lesions- causes decreased corneal sensation or lacrimal function

Excessive evaporation of tears

  • Increases with age Decreased tear production: Lacrimal gland dysfunction > reduced volume of aqueous fluid and hyperosmolarity of tear film/ocular surface > inflammation of the ocular surface

Increased evaporative loss: Meibomian gland dysfunction > altered lipid component of tear film > increased evaporation of tear fluid > inflammation of the ocular surface

Other causes: decreased blink function, medications, contact lenses, low humidity environments

Gritty/Burning/Foreign-Body sensation

  • Injection
  • Photophobia
  • Blurred vision
    • Often clinical Tear break up time
  • Schirmer’sTest Artificial tears/ocular lubricants

Severe cases- puncta can be plugged or cauterized to reduce tear drainage

Subconjunctival Hemorrhage

  • Systemic disease (HTN)
  • blood thinners
  • eye rubbing vigorous coughing or vomiting

Results from rupture of small vessels, collecting in the space between the sclera and the conjunctiva

  • Bright red eye to area of injury
  • Vision is not affected
  • Painless Clinical Resolves spontaneously (1-2wks) Episcleritis Inflammation of the episclera

Females and young to middle-aged adults most common

Usually a hypersensitivity response that causes vasodilatation, edema, and lymphocytic infiltration

  • Nonimmune (ex. Dry eye syndrome) Immune (ex. Systemic vasculitis or rheum disease)

Simple: sectoral, confined to a portion of the episclera (can be diffuse)

Nodular: raised and usually limited to just one area of the eyeball

  • Acute
  • 50% bilateral Redness vasodilatation of episcleral vessels
  • Irritation
  • Watering
  • Pain is unusual or very mild
  • Vision preserved Clinical Most resolve within 3 wks w/o treatment
  • Symptomatic relief Topical lubricants (artificial tears)-first line

Oral & topical NSAIDs (if persistent discomfort despite lubricants)

Topical glucocorticoids (if failure of lubricants and topical NSAIDs)

Red Eye Page 2 antihist i Ytrict ants (^1 2) wks 1 3 wks arttears