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Red Eye Clinical Medicine Topic Chart
Typology: Study Guides, Projects, Research
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Disease Cause Pathophys Symptoms Diagnosis Treatment Pictures Notes Hordeolum (Stye) Staphylococcus sp (usually S. aureus)
Poor eye or hand hygiene & eye rubbing
Increased risk if underlying skin condition
Sharing contaminated makeup
Blockage/inflammation/infection of Meibomian gland or Zeiss or Moll gland External is localized, red, swollen, acutely tender area on the upper or lower lid
Internal is a meibomian gland abscess that usually points onto the conjunctival surface of the lid
Clinical • Most resolve spontaneously Warm compresses (15 min, 4x/day)
Abx ointment (bacitracin or erythromycin)
rub or squeeze Chalazion May follow an internal hordeolum Chronic blockage/ granulomatous inflammation of a meibomian gland Hard, nontender swelling on the upper or lower lid with redness and swelling of adjacent conjunctiva Clinical Often resolves spontaneously
Promote drainage by using warm compresses
Incision and curettage or corticosteroid injection may be effective
Posterior Blepharitis Long-term inflammation > gland dysfunction and fibrosis > damage to the eyelid and ocular surface More common in adults and prevalence increases with age Chronic inflammation of the lid secondary to dysfunction of the Meibomian glands. Leads to instability of the tear film. Promotes bacterial growth (coag-neg staph, corynebacterium sp, cutibacterium acnes)
Flaking or scaling of the eyelid skin
Blurred vision improved with blinking
Trichiasis, Entropion/Ectropion
Dry eye disease (frequent complication)
Eyelid hygiene (mainstay)- warm compresses, lid massage, lid washing, artificial tears
Bacterial-antibiotic oint (bacitracin, erythromycin, azithromycin)
Demodex-oral ivermectin or topical tea tree oil scrub
Anterior Blepharitis Staphylococcal Type Fibrinous scales and crust around eyelashes; may alter meibomian gland secretion
Seborrheic Type Dandruff-like skin changes and greasy scales around base of eyelids/lashes
Demodex foliculorum Cylindrical dandruff or "sleeves"
Chronic inflammation of the lid margins Same as posterior Same as posterior Same as posterior Bacterial Conjunctivitis S. aureus most common in adults
Pseudomonas more common in contact lens wearers
More common in children than adults
Staining to assess for keratitis or corneal defect
Usually self-limited, (10- days)
Handwashing, separate towels
Abx eye gtts- Erythromycin oint, tobramycin, trimethoprim-polymyxin B; Ciprofloxacin gtts in contact lens wearers
Gonorrhea Conjunctivitis Neisseria gonorrhoeae Large amount of purulent discharge
Sometimes azithromycin/doxycycline for possible chlamydia co- infection
May require hospitalization for systemic and topical therapy and for monitoring- Keratitis and perforation can occur
Viral Conjunctivitis Adenovirus (many serotypes) May start unilateral but then progress to bilateral
Tuesday, April 4, 2023 8:00 AM Red Eye Page 1
Conjunctivitis pollen) response > local mast cell degranulation and release of chemical mediators (histamine, etc.) Itching, burning, gritty sensation, redness, watering
or (naphazoline/pheniramine) Antihistamine with mast cell stabilizing properties (olopatadine-Pataday)
Mast cell stabilizers (cromolyn-Opticrom)
Systemic illness (Sarcoidosis, Sjogren’s Syndrome)
Hormonal changes (primarily d/t decreased androgens)
Radiation therapy (if includes the orbit)
CN V or VII lesions- causes decreased corneal sensation or lacrimal function
Excessive evaporation of tears
Increased evaporative loss: Meibomian gland dysfunction > altered lipid component of tear film > increased evaporation of tear fluid > inflammation of the ocular surface
Other causes: decreased blink function, medications, contact lenses, low humidity environments
Gritty/Burning/Foreign-Body sensation
Severe cases- puncta can be plugged or cauterized to reduce tear drainage
Subconjunctival Hemorrhage
Results from rupture of small vessels, collecting in the space between the sclera and the conjunctiva
Females and young to middle-aged adults most common
Usually a hypersensitivity response that causes vasodilatation, edema, and lymphocytic infiltration
Simple: sectoral, confined to a portion of the episclera (can be diffuse)
Nodular: raised and usually limited to just one area of the eyeball
Oral & topical NSAIDs (if persistent discomfort despite lubricants)
Topical glucocorticoids (if failure of lubricants and topical NSAIDs)
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