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CNPR ACTUAL EXAM LATEST TEST BANK WITH QUESTIONS AND CORRECT VERIFIED
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Pharmaceuticals are arguably the most socially important healthcare product. - CORRECT ANSWER-True Pharmaceutical development is a high-risk undertaking, in which many promising leads prove disappointing. - CORRECT ANSWER-True Pharmaceutical sales are highest in which geographic regions? - CORRECT ANSWER-The U.S., Western Europe, and Japan. The U.S. accounts for about ______ of the world's pharmaceutical revenues. - CORRECT ANSWER-50% What event has fueled recent growth in the pharmaceutical industry? - CORRECT ANSWER- Population growth and increased life expectancies. According to your manual, what describes the predicted relationship between pharmaceutical companies and genomic research facilities? - CORRECT ANSWER-Partnerships between them will not prove immediately profitable. Prescription drug therapy is not cost-effective for insurance companies and insurance providers. - CORRECT ANSWER-False
The high price of healthcare is explained by the high price of medicines. - CORRECT ANSWER- False One of the oldest and least effective pharmaceutical marketing techniques is DTC (direct-to- consumer) advertising. - CORRECT ANSWER-False What influences the number of districts in a region? - CORRECT ANSWER-The regions population What is an example of the regionalization of healthcare delivery systems? - CORRECT ANSWER-California and Florida have different prescription reimbursement policies. The heart of a pharmaceutical sales team is the Regional Manager. - CORRECT ANSWER-False Most District Managers (DMs) did not start as representatives. - CORRECT ANSWER-False How many territories are in a typical district? - CORRECT ANSWER-8 to 12 What is the most effective method for grabbing market share? - CORRECT ANSWER- Comparative selling. Pharmaceutical reps mainly visit pharmacies. - CORRECT ANSWER-False It usually takes about 1-2 calls to a physician before he/she commits to prescribing your product. - CORRECT ANSWER-False The pharmacist may dispense a product other than what the physician prescribed. - CORRECT ANSWER-True
How does the Federal Food, Drug and Cosmetic Act (FFDCA) define a drug? - CORRECT ANSWER-Any substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease, or a substance other than food intended to affect the structure or function of the body. Most of the body's required vitamins must be taken from outside the body. - CORRECT ANSWER-True ADME testing measures the rate at which the body absorbs the drug, distributes it to the organs necessary to produce the desired effect, metabolizes it into waste material, and then excretes it from the body. - CORRECT ANSWER-True What field is ADME testing used in primarily? - CORRECT ANSWER-Pharmacokinetics. Placebo effects can lead to withdrawal symptoms. - CORRECT ANSWER-True On average, only about 5 of 4,000 drugs studied in laboratory are eventually studied in people. - CORRECT ANSWER-True Sublingual drugs are absorbed directly and almost immediately into the bloodstream. - CORRECT ANSWER-True What are 3 of the 7 rights of drug administration? - CORRECT ANSWER-The right patient, the right drug, the right dose. Pro-drugs are administered in active form, which is metabolized into an inactive form. - CORRECT ANSWER-False The kidney of an 85-year old person excretes drugs only ______ as efficiently as that of a 35- year old person. - CORRECT ANSWER-Around 50%
The normal age-related decrease in kidney function can help doctors determine an appropriate dosage based solely on a person's age. - CORRECT ANSWER-True What differentiates a caplet from a tablet? - CORRECT ANSWER-Caplets are shaped like capsules and have film coatings to aid in swallowing. Where will you find the legend, "Caution: Federal Law prohibits dispensing without a prescription."? - CORRECT ANSWER-On the label of all prescription drugs. What happens in slow acetylators? - CORRECT ANSWER-Drugs that are metabolized by N- acetyl transferase tend to reach higher blood levels and remain the body longer. About _______ of the people in the U.S. are slow acetylators. - CORRECT ANSWER-50% Drug-drug interactions are always harmful. - CORRECT ANSWER-False Smoking decreases the effectiveness of some drugs. - CORRECT ANSWER-True Because dietary supplements are not drugs, interactions with drugs are not a concern. - CORRECT ANSWER-False Ehrlich stated that an ideal drug (magic bullet) does not exist, would be aimed precisely at a disease site, and would not harm healthy tissues. - CORRECT ANSWER-True What is the difference between resistance and tolerance? - CORRECT ANSWER-Tolerance refers to a person's diminished response to a drug after repeated use, while resistance applies to microorganism's or cancer cell's abilities to withstand drug effects. Between 3% and 7% of hospital admissions in the U.S. are estimated to be for treatment of adverse drug reactions. - CORRECT ANSWER-True
What does the abbreviation BID denote? - CORRECT ANSWER-Twice a day What is the medical abbreviation for 'as needed'? - CORRECT ANSWER-PRN. Which components might cause patient's different reactions to brand name and generic drugs? - CORRECT ANSWER-Differences in inactive ingredients. All cells have a nucleus. - CORRECT ANSWER-False Name three things that affect drug response. - CORRECT ANSWER-The patient's genetic makeup, age, body size, and use of other drugs and dietary supplements. The patient's other conditions and diseases. Whether or not the patient takes the drug properly. Drug reactions are predictable because they do not occur after a person has been previously exposed to the drug one or more times without any allergic reactions. - CORRECT ANSWER- False What is the typical relationship between a drug's site of administration and site of action? - CORRECT ANSWER-They are usually somewhat removed from one another. What is CMAX? - CORRECT ANSWER-The peak plasma concentration on a measuring curve. Pharmacoprocesses are a main concept of clinical pharmacology. - CORRECT ANSWER-False Which is not a route of drug administration - buccal, intramuscular, sublingual, or transfugal?
- CORRECT ANSWER-Transfugal How are intradermal drugs delivered? - CORRECT ANSWER-By injection under the skin.
An injection of anesthetic directly into the bloodstream is an example of intravenous drug delivery. - CORRECT ANSWER-True What are the major organs of the gastrointestinal system? - CORRECT ANSWER-The mouth, esophagus, stomach, liver, pancreas, gallbladder, small and large intestines. Who is normally responsible for selling to distributors? - CORRECT ANSWER-NAMs. How often do secondary drugs wholesale distributors buy their drugs directly from manufacturers? - CORRECT ANSWER-Sometimes By FDA law, large chain pharmacies are not allowed to buy directly from drug manufacturers.
- CORRECT ANSWER-False Only 3 companies account for nearly 90% of all wholesale drug sales. - CORRECT ANSWER- True What type of sale bypasses the need for intermediary distributors? - CORRECT ANSWER- Manufacturer direct sales. What is a group purchasing organization (GPO)? - CORRECT ANSWER-An entity consisting of two or more hospitals or other health care entities that negotiates contracts on behalf of its members. Prescriptions dispensed by mail-order pharmacies are, on average, around _______ than those dispensed by retail pharmacies. - CORRECT ANSWER-3 times larger Which of the following is NOT a type of non-stock sale - a) brokerage sales b) dock-to-dock sales c) drop shipments
The FDA's Criteria for Equivalency requires the drugs contain identical amounts of the same inactive ingredients. - CORRECT ANSWER-True What list is generally considered the most reliable source of information on therapeutically equivalent drug products? - CORRECT ANSWER-"Approved Drug Products with Therapeutic Equivalence" Which of the following is an Orange Book rating a) AZ b) B c) BZ d) CZ - CORRECT ANSWER-b) B What is the term for chemical equivalents which, when administered in the same amounts, will provide the same biological or physiological availability as measured by blood and urine levels? - CORRECT ANSWER-Biologic equivalents. What term denotes a drug that is identical or bioequivalent to the originator brand-name drug in dosage form, safety, strength, route, quality, performance? - CORRECT ANSWER- Generic What term denotes the dispensing of an unbranded generic product for the product prescribed? - CORRECT ANSWER-Generic substitution. What is the duration of a patent challenge? - CORRECT ANSWER-180 days (6 months) How is a drug sample closet or cabinet like a grocery store shelf? - CORRECT ANSWER-The more visibility you can give your drug, the more likely it will be prescribed. Pharmaceutical reps do not typically store and secure their own drug samples. - CORRECT ANSWER-False
Sampling is sometimes the most important factor in a pharmaceutical rep's success. - CORRECT ANSWER-True The FDA approves storage conditions for drug products. - CORRECT ANSWER-True Pharmaceutical reps must always record the amount of drug samples left and obtain a signature for that amount. - CORRECT ANSWER-True What is prohibited by Section 503 of the Federal Food, Drug, and Cosmetic Act, as amended by the Prescription Drug Marketing Act? - CORRECT ANSWER-The sale, purchase, or trade or offer to sell, purchase, or trade prescription drug samples. The federal government does not regulate the drug sampling for a pharmaceutical rep. - CORRECT ANSWER-True Section 503 of the Federal Food, Drug, and Cosmetic Act permits hospitals to donate their prescription drug samples to qualified charitable organization. - CORRECT ANSWER-False Which entity issues monographs that define how drugs should be stored, and what variance is allowed in their shared contents? - CORRECT ANSWER-United States Pharmacopoeial Convention. Storage conditions for drug products are based on information supplied by the manufacturer. - CORRECT ANSWER-True Medications are usually unaffected by changes in temperature, light, humidity, and other environmental factors. - CORRECT ANSWER-False In which cases can degraded drugs sometimes still be used? - CORRECT ANSWER-When the amount of the remaining drug has not fallen lower than 85-90% of that stated on the label.
Which type system is the best way to deliver healthcare? - CORRECT ANSWER-A market- based system. How would increased pharmaceutical price controls affect the U.S. healthcare system? - CORRECT ANSWER-Increased price controls would stifle innovation. Which invests a greater percentage of sales in research than the biotech sector a) aerospace b) communications c) electronics d) none of these - CORRECT ANSWER-d) none of these What was the intent of the Bayh-Dole Act and the Stevenson-Wydler Technology Innovation Act? - CORRECT ANSWER-To hasten the commercialization of technologies that otherwise might not be used. What did the G10 Medicines Group recently report about the pharmaceutical industry in the European Union (EU)? - CORRECT ANSWER-There is poor collaboration between publicly- and privately-funded research centers. The aim of preclinical pharmacological studies is to obtain data on the safety and effectiveness of the lead compound. - CORRECT ANSWER-True Toxicity information in preclinical studies helps provide confidence about a drug's safety. - CORRECT ANSWER-True Pharmacological studies using animals are regulated under Good Laboratory Practice. - CORRECT ANSWER-True Why do drugs administered to patients only contain APIs? - CORRECT ANSWER-They don't.
A drug's vesicles affect it's ability to permeate membranes. - CORRECT ANSWER-True Through which barriers can lipid-soluble drugs usually pass? - CORRECT ANSWER-Cell membranes. How are weak acid drugs generally absorbed by the stomach? - CORRECT ANSWER-More quickly than weak basic drugs. Which route of administration does not completely bypass the liver? - CORRECT ANSWER- Rectal administration. Why are intravenous drug dosages easier to control than drugs administered transdermally?
- CORRECT ANSWER-The entire dose is available in the bloodstream to be distributed to the target site. A drug's lipid-solubility, polarity, and the __________ ___________ of the drug's target tissue affect it's distribution. - CORRECT ANSWER-vascular nature What medical term means "to apply the drug on the surface of the skin"? - CORRECT ANSWER-Transdermal. Carcinogenicity studies are carried out to identify the tumor-causing potential of a drug. - CORRECT ANSWER-True According to NIH ethical guidelines, what is the most important criteria in selecting subjects for clinical studies? - CORRECT ANSWER-Scientific objectives The members of the IRB/IEC must be experts in the topic of study. - CORRECT ANSWER-True
When designing and performing clinical trials, several ethical constraints must be considered. Which one of the following is NOT one of these ethical restraints a) geographic variations b) independent review c) scientific validity d) social value? - CORRECT ANSWER-Geographic variations. What is one way in which large molecule drugs differ from small molecule drugs? - CORRECT ANSWER-Large molecule drugs are mainly protein-based drugs that develop in biological systems such as living cells. Vaccines are types of small molecule drugs. - CORRECT ANSWER-False What is an advantage of attenuated vaccines over inactivated vaccines? - CORRECT ANSWER- Attenuated vaccines are less expensive to prepare. How are toxoids derived? - CORRECT ANSWER-From the toxins secreted by a pathogen. What is the estimated annual death toll in Malaria? - CORRECT ANSWER-1.5 to 3.5 million people. There are more white blood cells than red blood cells for the same volume in the human body. - CORRECT ANSWER-False How was insulin primarily obtained from the 1930s to the 1980s? - CORRECT ANSWER- Porcine and bovine extracts. Which of the following are not types of cytokines a) interferons
b) interleukins c) monokines d) all of these are types of cytokines - CORRECT ANSWER-All of these are types of cytokines. Which of the following is not a type of hormones a) amino acid derivatives b) blood glucose c) polypeptides d) steroids? - CORRECT ANSWER-Blood glucose. Describe the 'in vitro' gene therapy technique. - CORRECT ANSWER-Patients' genetically faulted tissues are removed, loaded with normal genes in vectors, and returned to the patients' bodies. Pluripotent stem cells can develop into many cell types, but not a new individual. - CORRECT ANSWER-True. Leukemia is a condition in which the stem cells in the bone marrow malfunction and produce an excessive number of immature white blood cells. - CORRECT ANSWER-True. Retroviruses are types of vectors used in gene therapy. - CORRECT ANSWER-True. Which of the following is not a type of stem cell a) multipotent b) pluripotent c) semipotent d) totipotent - CORRECT ANSWER-Semipotent.
The repeal of Hatch-Waxman is a recent formulary trend. - CORRECT ANSWER-False What did the Hatch-Waxman Act do? - CORRECT ANSWER-Make it easier for generic manufacturers to compete with R&D companies. What is opportunity cost? - CORRECT ANSWER-The value of a sacrificed alternative. The three primary entities that fund pharmaceuticals are employers, the government, and ______________. - CORRECT ANSWER-Individuals. A company's medical liaison can be a member of a P&T committee. - CORRECT ANSWER- False Almost 98% of employed Americans are now covered by a HMO, a preferred provider organization, or a point-of-service plan. - CORRECT ANSWER-False Pharmaceutical companies are more interested in acquiring and exploiting another's brands than in acquiring another's R&D and sales marketing assets. - CORRECT ANSWER-False Ideally, when should brand strategy development for a new drug begin? - CORRECT ANSWER- During Phase II clinical trials. An example of an expressive value is, "I own a BMW because I like feeling the road." - CORRECT ANSWER-False Which of the following is not an example of a functional value a) convenience b) efficacy c) safety d) uniqueness - CORRECT ANSWER-Uniqueness
It is rare for pharmaceutical companies to explore, develop, and promote expressive value with which patients might identify. - CORRECT ANSWER-True To be competitive, pharmaceutical brands must be distinctive. They must possess defining characteristics that are perceived by customers to be unique, attractive, and relevant to their needs. - CORRECT ANSWER-True With the global need for new drugs, pharmaceutical brand names are not subject to regulatory approval. - CORRECT ANSWER-False Over the last few decades, DTC advertising has become an essential marketing tactic for both large and small brands. - CORRECT ANSWER-True Which of the following most strongly influences physicians' prescribing habits a) doctors' personal experiences, and their patients' unique situations, b) DTC advertising c) other types of pharmaceutical marketing d) patients' opinions about DTC advertising? - CORRECT ANSWER-Doctors' personal experiences, and their patients' unique situations. Pharmaceutical companies spend more on promotional activities than on R&D. - CORRECT ANSWER-False A brand that treats a very common chronic condition would be well-served by mass-market print and TV ads. - CORRECT ANSWER-True How do companies use prescriber data? - CORRECT ANSWER-To conduct research. Under PhRMA Code, it is acceptable for modest meals to be provided for staff members attending educational events. - CORRECT ANSWER-True
