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ANATOMY, PHYSIOLOGY & PATHOLOGY
NOTES OF THE
NERVOUS SYSTEM
AND SPECIAL SENSES
FOURTH EDITION
CRANIAL NERVES PRE- SUMMARIZED NOTES
CRANIAL NERVES
Similarities Between Spinal Nerves & Cranial Nerves:
Cranial Nerves develop similar to Spinal Nerves, & hence have a similar
structural Organisation:
ļ¼ Sensory Cranial Nerves:
Similar to Afferent Spinal Nerves ā Sensory Cranial Nervesā
Dendrites are associated with peripheral sensory receptors &
their Cell Bodies are located in a Sensory Ganglia (Similar to
the Dorsal Root Ganglion in the spinal cord). Their axons
then terminate in the Sensory Nuclei of the Brainstem
(Similar to Dorsal Horn of Spinal Cord), and synapse with
one of the Ascending Pathways (Depending on the type of
stimulus):
- Touch ā Posterior Pathway
- Pain ā Spinothalamic
- Proprioception ā Spinocerebellar
ļ¼ Somatic Motor Cranial Nerves:
Similar to Efferent Spinal Nerves ā Motor Cranial Nerves
(Both Somatic & Branchial) have their Cell Bodies in grey-
matter Motor Nuclei in the Brainstem (Similar to Ventral
Horn of Spinal Cord). Their axons leave the brainstem &
directly innervate the Skeletal Muscles.
ļ¼ Visceral Motor Cranial Nerves:
ļ¼ Note: There are 6 pharyngeal arches, but the 5th only exists
transiently during embryonic growth
ļ¼ (No structures result from the 5th arch)
ļ¼ Appear ā4-5 weeks of development
Pharyngeal Arch Nerve Muscular Contributions 1 st^ ā āMandibularā Trigeminal (V) Muscles of Mastication:
- Ant. Digastric
- Mylohyoid
- Tensor Tympani
- Tensor Veli Palatini 2 nd^ ā āHyoid Archā Facial (VII) - Muscles of Facial Expression
- Post. Digastric
- Stylohyoid
- Buccinator 3 rd (^) Glossopharyngeal (IX) - Stylopharyngeus 4 th^ Vagus^ (X)^ -^ Cricothyroid^ Muscle
- Soft Palate Muscles 6 th^ Vagus^ (X)^ -^ Intrinsic^ Laryngeal^ Muscles
THE 12 CRANIAL NERVES ā Basic Overview:
ļ¼ Olfactory -Smell
ļ¼ Optic-Vision (Visual Acuity)
ļ¼ Oculomotor (āeye-moverā)-Controls 4 of the 6 eye muscles
ļ¼ Trochlear (āpulleyā)-Controls 1 of the extrinsic eye muscles ā
pulley shaped
ļ¼ Trigeminal-3-branched (Ophthalmic, Maxillary, Mandibular)
sensory fibers to the face & cornea + Mastication
ļ¼ Abducens (āabductā)-Controls the extrinsic eye muscle that abducts
the eyeball (lateral rotation)
ļ¼ Facial-Facial expression (Furrow Brow, Shut Eyes, Smile)
ļ¼ Vestibulocochlear-Hearing and balance (formerly the auditory
nerve)
ļ¼ Glossopharyngeal (ātongue & pharynxā)-Sensory Tongue and
pharynx (Gag reflex)
ļ¼ Vagus (āthe wandererā)-Mouth motor + parasympathetic effects in
the thorax & abdomen.
ļ¼ Accessory-Neck and shoulder muscles
Tongue, External Neck Muscles ā Sternocleidomastoid &
Trapezius)
Branchial Motor: āSpecial Visceral Efferentsā (SVE)
ļ¼ Innervate striated skeletal muscle derived from embryonic
pharyngeal arches. (Incl. Muscles of the Face, Palate,
Pharynx, Larynx & Mastication)
(Oculomotor, Trochlear, Trigeminal, Abducens, Facial, Glossopharyngeal, Vagus,
Accessory & Hypoglossal)
2. Involuntary (Visceral) Motor: āGeneral Visceral Efferentsā (GVE)
ļ¼ Innervate Smooth Muscle in vessels/glands/etc. Via a 2-neuron
approach; (Presynaptic fibres emerge from the brain as cranial
nerves, which then synapse in a parasympathetic ganglion. The
postsynaptic neurons then innervate the smooth muscles & glands
etc.)
ļ¼ Constitute the Cranial Outflow of the Parasympathetic Nervous
System.
(Oculomotor, Facial, Glossopharyngeal, Vagus)
3.Somatic Sensation: āGeneral Somatic Afferentsā (GSA)
ļ¼ (Touch, Pressure, Heat, Cold, etc)
(Trigeminal, Facial, Glossopharyngeal & Vagus)
4.Visceral Sensation: āGeneral Visceral Afferentsā (GVA)
ļ¼ (Blood Pressure & Blood-O2/CO2 from Carotid Sinus & Body,
plus Visceral Sensation from Pharynx, Larynx Trachea, Bronchi,
Lungs, Heart & GI Tract.)
(Oculomotor, Trigeminal, Facial, Glossopharyngeal, Vagus)
5.Special Sensation: āSpecial Somatic/Visceral Afferentsā (SSA/SVA)
ļ¼ (Vision, Taste, Smell, Hearing & Balance)
(Olfactory, Optic, Facial, Vestibulocochlear, Vagus)
YOU NEED TO KNOW WHICH NERVES CARRY EACH TYPE OF INFORMATION
Nerve Functional Components Location of Nerve Cell Bodies Cranial Exit Point Functions (major) I Olfactory nerve Special Sensory Olfactory Epithelium Cribriform Plate of The Ethmoid Bone Smell II Optic nerve Special Sensory Retinal Ganglion Optic Canal Vision and associated reflexes III Oculomotor nerve Somatic Motor Midbrain Superior Orbital Fissure Movements of eyes (Superiorly, Inferiorly & Medially) Visceral Motor (parasympathetic) Presynaptic: Midbrain Postsynaptic: Ciliary Ganglion Pupillary constriction and lens accommodation (parasympathetic) IV Trochlear nerve Somatic Motor Midbrain Superior Orbital Fissure Movements of eyes (Inferolaterally) V Trigeminal nerve
- V Ophthalmic Division General Sensory Trigeminal Ganglion Superior Orbital Fissure Sensation from Cornea, & V 1 Dermatome
- V2 Maxillary Division Foramen Rotundum Sensation from Maxillary Teeth, Nasal Mucosa, Maxillary Sinuses, Palate, & V 2 Dermatome
Visceral Sensory Superior Ganglion Visceral Sensation from Base of Tongue, Pharynx, Larynx Trachea, Bronchi, Heart, Esophagus, Stomach & Intestine ā L-Colic Flexure. Special Sensory Inferior Ganglion Taste (Epiglottis & Palate) General Sensory Superior Ganglion Sensation from the External Ear. XI Spinal Accessory Somatic Motor Spinal Cord Jugular Foramen Sternocleidomastoid & Trapezius Muscles XII Hypoglossal Somatic Motor Medulla Hypoglossal Canal Intrinsic & Extrinsic Muscles of the Tongue. Cranial Nerve Nuclei:
Location:
ļ¼ CN I (Olfactory) & II (Optic) = Are both extensions of the
Forebrain.
ļ¼ CN III ā XII (All others) = They originate from Nuclei located in
the Brainstem.
Organisation:
ļ¼ Nuclei of similar Functional Components (Ie: General
Somatic/Visceral Motor or General Somatic/Visceral Sensory) are
generally aligned into functional columns in the brainstem.
Cranial Nerve: Receptor Types: Sensory Ganglia: Olfactory Olfactory (Smell) Olfactory Epithelium Optic Retinal (Vision) Retina of the Eye Trigeminal Somatosensory Trigeminal Ganglion Facial Somatosensory Geniculate Ganglion Vestibulocochlear Equilibrium & Hearing Vestibular Ganglion & Spiral Ganglion Glossopharyngeal Somatosensory, Visceral & Taste Inferior Ganglion Vagus Somatosensory, Visceral & Taste Superior & Inferior Ganglion
Parasympathetic Ganglia of Cranial Nerves:
Cranial Nerve Ganglion Location Main Distribution Oculomotor Ciliary Between the Optic Nerve & the Lateral Rectus Muscle of Eye Ciliary Muscle & Pupillary Sphincter of Eyes Facial Pterygopalatine In Pterygopalatine Fossa; Just anterior to the opening of the Pterygopalatine Canal. Lacrimal (Tear) Gland Submandibular Just inferior to Submandibular Salivary Duct Sublingual & Submandibular Salivary Glands Glossopharyngeal Otic Between Tensor Veli Palatini & Mandibular Nerve (Just anterior to Foramen Ovale of Sphenoid Bone) Parotid Salivary Gland.
Note:Sympathetic Input is important for the Dual Innervation setup of the
Autonomic NS. The Sympathetic Fibres ascending from the Superior Cervical
Sympathetic Ganglion hitch a ride with the Parasympathetic Cranial Nerves and
follow them to their targets
II.Optic:
Function:
o Purely Special Sensory; Carry Afferent Impulses of Vision
Origin & Course:
ļ¼ Fibres arise from the Retina and form the Optic Nerve
ļ¼ The Optic Nerve passes through the Optic Canal of the
Orbit.
ļ¼ The Optic Nerves converge to form the Optic Chiasma
where half of each nerveās fibres cross over & continue on
as Optic Tracts
ļ¼ The Optic Tracts synapse in the Thalamus, & Thalamic
fibres extend to the Visual Cortex
Origin & Course:
ļ¼ Fibres arise from the Midbrain and pass through the Superior
Orbital Fissure to the Eye.
V.Trigeminal:
Note: Has 3 Divisions (Ophthalmic, Maxillary & Mandibular), each with
different specific functions & courses through the skull.
Function:
ļ¼ Mostly Somatosensory (From Face)
ļ¼ Some Branchial Motor
Origin & Course:
ļ¼ Ophthalmic ā Fibres run from Face ā Through Superior Orbital
Fissure ā Pons.
ļ¼ Maxillary ā Fibres run from face ā Through the Foramen
Rotundum ā Pons.
ļ¼ Mandibular ā Fibres pass through the Foramen Ovale
VIII.Vestibulocochlear:
Function:
ļ¼ Special Sensory:
ļ§ Vestibular Branch ā Sense of Equilibrium/Balance.
ļ§ Cochlear Branch ā Sense of Hearing.
Origin & Course:
ļ¼ Fibres arise from the Vestibule & the Cochlear of the Inner Ear of
the Temporal Bone & pass through the Internal Acoustic Meatus
and enter the brainstem @ the Pons-Medulla Border.