Understanding Nucleic Acids: The Role of DNA and RNA in Cellular Activities, Study notes of Chemical Processes

Explore the world of nucleic acids, focusing on DNA and RNA. Learn about their structures, functions, and the role they play in controlling cellular activities, including protein production and cell division. Discover the importance of bases, sugar types, and the base-pair rule.

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!Nucleic acids
DNA -"The Double Helix
Recall that the nucleus is a small spherical, dense body in a cell.! It is
often called the "control center" because it controls all the activities of
the cell including cell reproduction, and heredity.! Chromosomes are
microscopic, threadlike strands composed of the chemical DNA (short for
deoxyribonucleic acid).! In simple terms, DNA controls the production of
proteins within the cell.! These proteins in turn, form the structural units
of cells and control all chemical processes within the cell.! Think of proteins
as the building blocks for an organism, proteins make up your skin, your
hair, and parts of individual cells. The proteins that are made largely
determine how you look. The proteins that will be made for your body are
determined by the sequence of DNA in the nucleus.
What important polymer is located in the nucleus? _____DNA___
___DNA_____ is the instructions for making a cell's __proteins_____.
Chromosomes are composed of genes, which is a segment of DNA that
codes for a particular protein, which in turn codes for a trait.! Hence you
hear it commonly referred to as the gene for baldness or the gene for blue
eyes.! Meanwhile, DNA is the chemical that genes and chromosomes are
made of. DNA is called a nucleic acid because it was first found in the
nucleus.! We now know that DNA is also found in some organelles such as
the mitochondria and chloroplasts. It is the DNA in the nucleus that
actually controls the cell's workings.
genes __ on chromosomes code for specific ___ traits ___ in a cell.
DNA is also found in _ mitochondria _ and chloroplasts _.
In 1953, James Watson and Francis Crick established the structure
of DNA.! The shape of DNA is a double helix, which is like a twisted ladder.
The sides of the ladder are made of alternating sugar and phosphate
molecules.! The sugar is a pentose called deoxyribose. Color all the
phosphates pink (one is labeled with a "p"). Color all the deoxyribose
sugars blue (one is labeled with a "D").
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! Nucleic acids

DNA - The Double Helix Recall that the nucleus is a small spherical, dense body in a cell. It is often called the "control center" because it controls all the activities of the cell including cell reproduction, and heredity. Chromosomes are microscopic, threadlike strands composed of the chemical DNA (short for deoxyribonucleic acid). In simple terms, DNA controls the production of proteins within the cell. These proteins in turn, form the structural units of cells and control all chemical processes within the cell. Think of proteins as the building blocks for an organism, proteins make up your skin, your hair, and parts of individual cells. The proteins that are made largely determine how you look. The proteins that will be made for your body are determined by the sequence of DNA in the nucleus. What important polymer is located in the nucleus? _____DNA___ ___DNA_____ is the instructions for making a cell's __proteins_____. Chromosomes are composed of genes , which is a segment of DNA that codes for a particular protein, which in turn codes for a trait. Hence you hear it commonly referred to as the gene for baldness or the gene for blue eyes. Meanwhile, DNA is the chemical that genes and chromosomes are made of. DNA is called a nucleic acid because it was first found in the nucleus. We now know that DNA is also found in some organelles such as the mitochondria and chloroplasts. It is the DNA in the nucleus that actually controls the cell's workings. genes __ on chromosomes code for specific ___ traits ___ in a cell. DNA is also found in _ mitochondria _ and chloroplasts _. In 1953, James Watson and Francis Crick established the structure of DNA. The shape of DNA is a double helix, which is like a twisted ladder. The sides of the ladder are made of alternating sugar and phosphate molecules. The sugar is a pentose called deoxyribose. Color all the phosphates pink (one is labeled with a "p"). Color all the deoxyribose sugars blue (one is labeled with a "D").

What is meant by a double helix? _2 strands of DNA in a helix shape are bound together________ Name a pentose sugar. __deoxyribose_____ The sides of DNA are made of deoxyribose _ and _ phosphates _. The rungs of the ladder are pairs of 4 types of nitrogen bases. The bases are known by their coded letters --- A, G, T, and C. These bases always bond in a certain way. Adenin e will only bond to thymine. Guanine will only bond with cytosine. This is known as the "Base-Pair Rule. " The bases can occur in any order along a strand of DNA. The order of these bases is the code that contains the instructions. For instance, ATGCACATA would code for a different gene than AATTACGGA. A strand of DNA contains millions of bases. (For simplicity, the image only contains a few.) What makes up the "rungs" of DNA? _ nitrogenous bases __ What will pair with adenine? _ thymine ___ Color the thymines orange. " Color the adenines green. " Color the guanines purple. " Color the cytosines yellow. " Note that that the bases attach to the sides of the ladder at the sugars and not the phosphate. The DNA helix is actually made of repeating units called nucleotides. Each nucleotide consists of three molecules : a sugar (deoxyribose), a phosphate, which links the sugars together, and then one of the four bases. Two of the bases are purines - adenine and guanine. The pyrimidines are thymine and cytosine. Note that the pyrimidines are single ringed and the purines are double ringed. Color the nucleotides using the same colors as you colored them in the double helix. Nucleotides are made of a pentose _ deoxyribose _, a _ phosphate _, and a nitrogen-containing _ base __. Name 2 bases with double C-N rings. _ adenine and guanine ___

Messenger RNA _, not DNA can leave the nucleus through _ nuclear pores in the nuclear envelope. Proteins are made at the __ ribosomes __. The Blueprint of Life Every cell in your body has the same "blueprint" or the same DNA. Like the blueprints of a house tell the builders how to construct a house, the cellular DNA "blueprint" tells the cell how to build the organism. Yet, how can a heart be so different from a brain if all the cells contain the same instructions? Although much work remains in genetics, it has become apparent that a cell has the ability to turn off most genes and only work with the genes necessary to do a job. We also know that a lot of DNA apparently is nonsense and codes for nothing. These regions of DNA that do not code for proteins are called "introns," or sometimes "junk DNA.” The sections of DNA that do actually code for proteins are called "exons." _ Introns __ are non-coding segments of DNA. Questions:

  1. Write out the full name for DNA. deoxyribonucleic acid
  2. What is a gene? a segment of DNA that codes for a particular protein
  3. Where in the cell are chromosomes located? nucleus
  4. DNA can be found in what organelles in the cell? Mitochondria and chloroplasts
  5. What two scientists established the structure of DNA? Watson and Crick
  6. What is the shape of DNA? Double helix
  7. The sides of the DNA ladder are composed of what?Sugar (deoxyribose) & phosphate
  8. The "rungs" of the DNA ladder are made of what? Nitrogenous bases
  9. What sugar is found in DNA? In RNA? Deoxyribose & ribose
  10. How do the bases bond together? A bonds with T G bonds with ___ C ___
  11. The two purines in DNA are__adenine____ and guanine__.
  12. DNA is made of repeating units called nucleotides__.
  1. Why is RNA necessary to act as a messenger? Why can't the code be taken directly from the DNA? DNA is too big to leave the nucleus
  2. Proteins are made where in the cell? On the ribosome in the cytoplasm
  3. How do some cells become brain cells and others become skin cells, when the DNA in ALL the cells is exactly the same? most genes are turned off
  4. Why is the DNA molecule referred to as the "blueprint of life"? It tells the cell how to build the organism !