DNA MUTATIONS PRACTICE WORKSHEET, Cheat Sheet of Mathematics

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protein synthesis:
What is the first step of protein synthesis? Transcription
What is the second step of protein synthesis? Translation
Where does the first step of protein synthesis occur? Nucleus
Where does the second step of protein synthesis occur? Cytoplasm/Ribosome
Nitrogen bases are read ______ bases at a time. Three (
)
The bases on the mRNA strand are called ____________. Codons
The bases on tRNA are called ____________. Anticodons
What is the start codon? AUG
What are the stop codons? UAA, UAG, UGA
A bunch of amino acids attached together is called a __________________________
Polypeptide / Protein
DNA: AGA CGG TAC CTC CGG TGG GTG CTT GTC TGT ATC CTT CTC AGT ATC
mRNA: UCU GCC AUG GAG GCC ACC CAC GAA CAG ACA UAG GAA GAG UCA UAG
Protein: Start (Met) - Glu - Ala - Thr - His - Glu - Gln - Thr - STOP
DNA is located in the โœ… nucleus.
โœ… Transcription converts DNA into mRNA.
โœ… mRNA is used to carry the genetic code from DNA to the ribosomes.
โœ… rRNA makes up the ribosome.
โœ… RNA uses uracil instead of thymine.
โœ… Amino acids make up a protein.
Transcription takes place in the โœ… nucleus.
tRNA is used in โœ… translation.
tRNA uses โœ… anticodons to match to the mRNA.
Proteins are made at the โœ… ribosome.
โœ… tRNA attaches the amino acids into a chain.
tRNA is found in the โœ… cytoplasm.
โœ… Translation converts mRNA into a protein.
Translation takes place in the โœ… cytoplasm.
1. Three major differences between DNA & RNA:
a) Sugar: DNA has deoxyribose; RNA has ribose.
b) Strands: DNA is double-stranded; RNA is single-stranded.
c) Bases: DNA uses Thymine (
); RNA uses Uracil (
).
YouTube
YouTube
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3. Point of DNA replication: To create an identical copy of the DNA molecule before cell division.
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protein synthesis: What is the first step of protein synthesis? Transcription What is the second step of protein synthesis? Translation Where does the first step of protein synthesis occur? Nucleus Where does the second step of protein synthesis occur? Cytoplasm/Ribosome Nitrogen bases are read ______ bases at a time. Three ( ) The bases on the mRNA strand are called ____________. Codons The bases on tRNA are called ____________. Anticodons What is the start codon? AUG What are the stop codons? UAA, UAG, UGA A bunch of amino acids attached together is called a __________________________ Polypeptide / Protein DNA: AGA CGG TAC CTC CGG TGG GTG CTT GTC TGT ATC CTT CTC AGT ATC mRNA: UCU GCC AUG GAG GCC ACC CAC GAA CAG ACA UAG GAA GAG UCA UAG Protein: Start (Met) - Glu - Ala - Thr - His - Glu - Gln - Thr - STOP DNA is located in the โœ… nucleus. โœ… Transcription converts DNA into mRNA. โœ… mRNA is used to carry the genetic code from DNA to the ribosomes. โœ… rRNA makes up the ribosome. โœ… RNA uses uracil instead of thymine. โœ… Amino acids make up a protein. Transcription takes place in the โœ… nucleus. tRNA is used in โœ… translation. tRNA uses โœ… anticodons to match to the mRNA. Proteins are made at the โœ… ribosome. โœ… tRNA attaches the amino acids into a chain. tRNA is found in the โœ… cytoplasm. โœ… Translation converts mRNA into a protein. Translation takes place in the โœ… cytoplasm.

  1. Three major differences between DNA & RNA: a) Sugar: DNA has deoxyribose; RNA has ribose. b) Strands: DNA is double-stranded; RNA is single-stranded. c) Bases: DNA uses Thymine ( ); RNA uses Uracil ( ). YouTube YouTube
  2. Point of DNA replication: To create an identical copy of the DNA molecule before cell division.
  1. When & where does replication occur: Occurs during the S-phase (synthesis) of interphase in the nucleus.
  2. Point of transcription: To create an mRNA copy of a specific gene's DNA sequence.
  3. Three nucleotides on mRNA: Codon.
  4. mRNA codons used to find: Amino acids (to build proteins).
  5. Molecule with anti-codon: tRNA (transfer RNA).
  6. Importance of tRNA: It brings the correct amino acid to the ribosome based on the mRNA codon.
  7. Translation location: Cytoplasm on a ribosome.
  8. Point of translation: To synthesize proteins by decoding the mRNA message.
  9. Transcription + Translation: Gene expression.
  10. DNA sequence change: Mutation.
  11. Mutation agent: Mutagen.
  12. Examples of causes: UV radiation, chemicals (e.g., cigarette smoke), radiation (X-rays), and viruses.
  13. Two types of mutations: Khan Academy Khan Academy

Point Mutation (Substitution): One base is swapped for another (e.g., Sickle Cell Anemia). Frameshift Mutation (Insertion/Deletion): Base(s) are added or removed, shifting the reading frame (e.g., Cystic Fibrosis). Which is more destructive? Chromosomal mutations are generally more destructive than gene mutations. RevisionDojo RevisionDojo Why? While a gene mutation typically affects only a single protein, a chromosomal mutation involves large segments of DNA that contain dozens or hundreds of genes. Changing the structure or number of chromosomes disrupts the genetic balance of the entire genome. RevisionDojo RevisionDojo +

  1. Difference between Gene & Chromosome Mutations Gene Mutation: A small-scale change in the nucleotide sequence of a single gene (e.g., a point mutation). Chromosome Mutation: A large-scale change affecting the structure or number of entire chromosomes, often impacting many genes at once.
  2. Types of Chromosome Mutations a. Deletion: A segment of the chromosome is lost or removed.