Epigenetic Small Molecules: Modulators and Inhibitors for Epigenetic Proteins, Slides of Biology

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epigenetic small

molecules

In the field of epigenetics, changes in DNA methylation and histone

post-translational modification patterns are the focus of research. Many

proteins are involved in the process of DNA methylation and histone

modification, some of which participate in binding modified DNA or

histones, and others can catalyze or remove those specific chemical

groups. These epigenetic proteins have become emerging drug

development targets for many diseases.

Creative BioMart has a series of small-molecule epigenetic modulators

(including activators, antagonists, and inhibitors), and these include

targets to DNA methyltransferases (DNMTs), DNA demethylases,

histone methyltransferases (HMTs), histone demethylases (HDMs),

histone acetyltransferases (HATs), histone deacetylases (HDACs),

histone phosphorylation-related enzymes and

reader domain-containing proteins. Because epigenetic regulation plays

an important role in the occurrence and development of diseases such

as cancer, these small-molecule epigenetic modulators are important

tools for researchers to perform epigenetic drug discovery projects.

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Bioactive Small Molecules

• Epigenetics Small Molecules - Methyltransferase Modulators & Inhibitors - Demethylase Modulators & Inhibitors - Histone Acetyltransferase (HAT) Modulators & Inhibitors - Histone Deacetylase (HDAC) Modulators & Inhibitors - Histone Phosphorylation Modulators & Inhibitors - Reader Domain Modulators & Inhibitors

Excerpt from:

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products/bioactive-small-molecules/epigenetics-small-

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