

Study with the several resources on Docsity
Earn points by helping other students or get them with a premium plan
Prepare for your exams
Study with the several resources on Docsity
Earn points to download
Earn points by helping other students or get them with a premium plan
1 / 3
This page cannot be seen from the preview
Don't miss anything!


Gland/hormone Function Dysfunction/Disorders Chemical Composition Anterior Pituitary Growth Hormone (GH) (somatotropism) Stimulates the growth of all organs in the body, mobilizes food molecules increasing the blood glucose concentration Hypersecretion results in gigantism and acromegaly Protein Melanocyte-stimulating hormone (MSH) Stimulates synthesis and dispersion of the pigment melanin in the skin Hyposecretion results in the darkening of the skin Protein Adrenocorticotrophic hormone (ACTH) Stimulates secretion of adrenal cortex hormones Hypersecretion or hyposecretion of adrenal cortex Polypeptide Follicle-stimulating hormone (FSH) Males: Stimulates production and growth of sperm in seminiferous tubules of testes Female: Stimulates development of follicles in ovaries and secretion of estrogen Hyposecretion inhibits sexual development and causes sterility Glycoprotein Luteinizing hormone (LH) Males: stimulates secretion of testosterone by the interstitial cells of the testes Female: Stimulates the secretion of estrogen stimulates maturation of ovarian follicle and ovum, ,triggers ovulation, and stimulates the development of the corpus luteum or lutenization Hyposecretion inhibits sexual development and causes sterility Glycoprotein Prolactin Stimulates breast development during pregnancy and milk development after pregnancy Hypersecretion causes inappropriate lactation in non-nursing women and in men. Hyposecretion causes insufficient lactation in nursing women Protein Posterior Pituitary (synthesized in Hypothalamus but released in posterior pituitary) Antidiuretic hormone (ADH) Stimulates water retention by the kidneys Hypersecretion results in abnormal water retention Hyposecretion causes diabetes insipidus Peptide Oxyotocin Stimulates uterine contractions at the end of pregnancy and the release of milk into the ducts of the breast Hypersecretion causes inappropriate ejection of milk in lactating women Hyposecretion may cause prolonged or difficult labor and delivery Peptide
Hypothalamus (Releasing hormones) Stimulates anterior pituitary to release hormones Hypersecretion causes hypersecretion by anterior pituitary Hyposecretion causes hyposecretion by pituitary Protein Thyroid Thyroxine (T 4 ) and thiiodothyronine (T 3 ) Stimulates energy metabolic activities of cells Hypersecretion causes hyperthyroidism, Graves disease Hypersecretion causes hypothyroidism, (pre-adult) cretinism, (adult) myxedema, goiter Iodinated protein Calcitonin Inhibits breakdown of bone and causes decreases in blood calcium concentrations Hypersecretion can cause hypocalcemia Hyposecretion can cause hypercalcemia Polypeptide Parathyroid Parathyroid hormone (PTH) Stimulates the breakdown of bone and causes increase in blood calcium concentrations Hypersecretion can cause hypercalcemia Hyposecretion can cause hypocalcemia Polypeptide Adrenal Cortex Mineralocorticoids aldosterone Regulate electrolyte and fluid homeostasis or balance Hypersecretion causes increased water retention Hyposecretion causes abnormal water loss or dehydration Steroid Cortisol (hydrocortisone)and other glucocorticoids Stimulates gluconeogenesis, causing an increase in blood glucose concentrations and has anti-inflammatory, anti-immunity, and anti-allergy effects Hypersecretion causes Cushing’s Syndrome Hyposecretion causes Addison’s disease Steroid Sex hormones (androgens) Stimulate sexual drive in females but have little effects in males Hypersecretion causes premature sexual development in females and masculinization of females Hyposecretion has no significant effect Steroids Adrenal Medulla Epinephrine (adrenalin) and norepinephrine Intensifies and prolongs the sympathetic response during stress Hypersecretion causes effects of stress Hyposecretion has no significant effect Catecholamines (amino acid derivatives) Pancreatic Islets Glucagon Stimulates glycogenolysis causing an increase in blood glucose concentration Uncertain Polypeptides Insulin Promotes glucose entry into cells causing decrease in blood glucose concentration Hypersecretion causes severe insulin shock or hypoglycemia Polypeptides