Two
phases:
Oxidative
vs
non-oxidative
Nonoxidative
Oxidative
Main
products
->
NADPH
+
ribose
S-phosphate
phase
phase
Mr
T
NADPH
NAPPH
-
electron
donor
Reductive
blosynthesis
of
fatty
acids
+
stevolds
Repair
of
oxidative
damage
I
Ribosesphosphate
->
biosynthetic
precursor
of
nucleotides
in
the
case
here
are
writer
intere
Used
in
DNA+RNA
synthesis
or
synthesis
of
some
coenzymes
Precursors
Oxidative
Phase
Ribuloses,
phosphate
RiboseS-phosphate
low
-
so
are
Generates
NADPH
+
Pentose
↓
Ribulose
-
5-phosphate
can
be
used
to
generate
ribose
-
5-phosphate
givgeny
genate
(shappn+
nt
for
DNA/RNA
as
well
as
xylulose
-
S-phosphate
for
non-
Nucleotides,
coenzymes,
nat
Oxidative
ppp
DNA,
RNA
noc/
lactone
*
NADPH
regulates
partitioning
Into
Glycolysis
lactonase
an
a
6-phosphogluconate
(meant
t
versus
Pentose
Phosphate
Pathway
*
a
0-
CH20H
nono.
ie"
phosphabetes
conopo..**
at
e
Glucose
coropa.
Bbsphase
-
the
internate
materia
↓
CH2OPOS-
Xylulose
S-phosphate
Non-Oxidative
Phase
Glucosate
polysis,
A
*
Regenerates
G-G-P
from
R-5-p*
No
ATP
used
in
nonoxidative
phase
pentose
⑪
used
in
tissues
(requiring
more
NADPH
than
R-S-P)
phosphate
to
glucose
6
phosphate
such
as
liver
+
adipose
tissue
complete
conversion
of
ribose
-
5-
onosphate,
in
on
"
requires
6
RSP
to
make
5
G6P
pathway
*Non
oxidative
Phase
results
in
Net
Loss
of
Carbons,
but
not
energy
*
6-Phospho-
gluconolactone
oxidative
reactions
of
pentosephosphate
pathway
B
Ribose
----
one
nice
risen
oste
C
6C
↓
"
S-phosphate
s
⑭
"
Isomerase
Wa
camerase
by
etolase
Adolase
v
↑
phosphone
see
-
X
ylulose
Glyceraldehyde
Erythroes
fructose
⑤s
/
>
NADPH
-
1
S-phosphate
a-phosphate
6-phosphate
fructose
16-
Ma
i
bisphosphatase
/7
Pentose
⑲Ketolase"ancosphate
S-phosphate
dyceraldely
be
Xylulose
3-phosphate
T
phosphates
TC
