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NCM LECTURE NURSING NOTES, Lecture notes of Nursing

Mindanao State University - Iligan Institute of Technology (MSUIIT)Nursing

The process of inflammation and healing in the body. It explains the different types of inflammation, cellular healing, and the systemic response to inflammation. The document also touches on the topic of immunity. It provides a list of chemical substances involved in inflammation and their functions. informative and provides a basic understanding of the topic.

Typology: Lecture notes

2020/2021

Available from 07/04/2023

reca-kathleen-seccion
reca-kathleen-seccion ๐Ÿ‡ต๐Ÿ‡ญ

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โ— Vasodilation and increased permeability of blood vessels
โ— Phagocyte emigration
โ— Tissue repair
A. Inflammation
โ— Capillary dilation, fluid exudation, neutrophil migration
B. Suppuration
โ— Development of suppurative or purulent exudate containing degraded neutrophils and
tissue debris.
C. Abscess formation
โ— Walling off of the area of purulent (pus) exudate to form an abscess.
3 Chemical substances
1. Histamine - vasodilation, increase capillary permeability
2. Kinis - do- attract neutrophils
11/18/22, 3:12 PM
Page 4 of 29
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โ— Vasodilation and increased permeability of blood vessels โ— Phagocyte emigration โ— Tissue repair A. Inflammation โ— Capillary dilation, fluid exudation, neutrophil migration B. Suppuration โ— Development of suppurative or purulent exudate containing degraded neutrophils and tissue debris. C. Abscess formation โ— Walling off of the area of purulent (pus) exudate to form an abscess. 3 Chemical substances

  1. Histamine - vasodilation, increase capillary permeability
  2. Kinis - do- attract neutrophils
  1. Prostaglandins - increase capillary permeability Systemic Response to Inflammation โ— Fever - endogenous pyrogenes (internal substances that cause released from neutrophils (fever); macrophages โ— Pyrogenes - reset the hypothalamic thermostat which controls body temp and produce fever โ— Leukocytosis - occur to provide the body with greater ability to fight infection
  • malaise, loss of appetite, aching weakness Types of Inflammation โ— Acute - local vascular and exudative changes protective 2 weeks; subsides - healing โ— Chronic - persists, not beneficial, not protective months, years debilitating and long lasting effect repair โ— Subacute - between acute and chronic Cellular Healing โ— Proceeds after the inflammatory debris is removed Healing:
  1. Regeneration - proliferation of the same type of cells as destroyed.
  2. Replacement - cells of another type, fill in the tissue defect - scar formation Healing by Regeneration
  3. Labile cells - multiply constantly
  4. Permanent cells - neurons
  5. Stable - not shed and do not need replacement; if destroyed they will regenerate
  • kidneys, liver, pancreas Healing by Replacement
  1. Primary Intention - wound is clean and dry
  • healed within a week
  1. Secondary Intention - wound or defect is larger and gaping and has necrotic or dead material
  • MI โ— https://www.youtube.com/watch?v=gIlZHyptUPM&t=6s Immunity โ— refers to the bodyโ€™s specific protective response to an invading foreign agent or organism