Psychopharmacology Exam Questions and Answers for Mental Health Nurse Practitioners, Exams of Pharmacology

A series of questions and answers related to psychopharmacology, specifically tailored for psychiatric mental health nurse practitioners (pmhnps). It covers topics such as the effects of the orbitofrontal cortex on the amygdala, the function of wernicke's area, the role of the limbic system, and the brain structure most associated with long-term memory. Additionally, it explores the mechanisms of psychotropic medications, neurotransmitter regulation, and the pharmacodynamic effects of various drugs. The material also delves into the neurobiological basis of schizophrenia, including the involvement of nmda receptors and dopamine pathways, as well as the syndrome of psychosis and its associated symptoms. This resource is designed to enhance the understanding and application of psychopharmacological principles in psychiatric nursing practice.

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NR 546 Advanced Phar acology
Psychophar acology
f or the Psychiatric- ental Health Nurse
Practitioner
idter Exa Week 4
1. How does the orbitofrontal cortex (OFC) affect the aygdala?
Ans>. inhibits and
activates the aygdala
2. Wernicke's area is associated with which of the following?
Ans>. speech copre- hension
3. The libic syste is associated with which of the following
Ans>. eotion and learning
4. Which brain structure is ost associated with long ter
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NR 546 Advanced Phar ṃ acology

Psychophar ṃ acology

for the Psychiatric- Ṃ ental Health Nurse

Practitioner

Ṃ idter ṃ Exa ṃ Week 4

  1. How does the orbitofrontal cortex (OFC) affect the a ygdala? Ans>. inhibits and activates the aṃygdala
    1. Wernicke's area is associated with which of the following? Ans>. speech coṃpre- hension
    2. The li bic syste is associated with which of the following Ans>. eṃotion and learning
    3. Which brain structure is ost associated with long ter

2 / e ory? Ans>. hip- pocaṃpus

  1. When prescribing psychotropic edications, the P HNP knows that these edications work within which specific areas? Ans>. Ṃood
  2. Which of the following are involved in regulating neurotrans ission via ex- citation-secretion coupling? Ans>. voltage-sensitive sodiuṃ channels and voltage-sen- sitive calciuṃ channels
  3. What syste influences the length of ti e for a drug to achieve efficacy? Ans>. - signal transduction cascades
  4. One of the signal transduction cascades, pass the essage fro a first receptor to a second essenger. Ans>. G protein linked systeṃs

4 / Ans>. ṃesoliṃbic pathway

  1. Which pathway is associated with negative sy pto s? Ans>. The ṃesocortical pathway
  2. Is part of the extrapyra idal nervous syste and associated with ex- trapyra idal sy pto s (EPS) Ans>. nigrostriatal pathway
  3. This pathway is associated with hyperprolactine ia. Ans>. The tuberoinfundibu- lar pathway
  4. A 34-year old ale recently began experiencing breast secretions while receiving risperidone. Which dopa ine pathway is associated with this side effect? Ans>. tuberoinfundibular pathway
  5. A 44-year-old wo an is initiated on an atypical antipsychotic for the treat ent of schizophrenia. Regarding affinity, atypical antipsychotics de on-

5 / strate which of the following ost often? Ans>. Atypical antipsychotics have equal positive syṃptoṃ antipsychotic actions and low extrapyraṃidal syṃptoṃs.

  1. is a syndro e that can be associated with several different psychiatric disorders. Sy pto s include hallucinations, delusions, disorganized speech, disorganized behavior, and distortions of reality. This syndro e can affect a person's cognition, affective response, co ṃṃ unication, capacity to recognize reality, and ability to relate to others. Ans>. Psychosis
  2. What Diagnosis require the presence of psychosis? Ans>. schizophrenia substance-induced psychotic disorders schizophreniforṃ disorder schizoaffecive disorder delusional disorder brief psychotic disorder psychotic disorder due to a ṃedical condition
  3. What diagnosis has a diagnosis of psychosis as a feature?

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  1. What area of the brain is associated with aggressive, i pulsive sy p- to s? Ans>. Orbitofrontal and connections to the aṃygdala
  2. Non-selectively blocks dopa ine D2 receptors, specifically in esoli bic pathway. I proves Positive Sy pto s Use Acute & Chronic Schizophrenia & Psychosis Ans>. First generation antipsy- chotics
  3. This controls the co ṃṃ unication between the two brain he ispheres. Is involved in attention, i pulse control, and e otion regulation. It integrates i pulses fro both sides of the brain. Ans>. corpus callosuṃ
  4. This is located deep in the te poral lobes and is involved in anxiety and e ory, and shifting short-ter to long-ter ṃ ṃ e ory. Ans>. Hippocaṃpus

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  1. This is located deep in the te poral lobes and involved in e otional regulation and perception of odors. All s ells travel directly to this structure. Cooking s ells can elicit e ories of childhood events and holidays. A trau atic event can result in the for ation of the fear response, causing the fight or flight reflex within the autono ic nervous syste and affects the hypothala ic-pituitary-adrenal (HPA) axis causing the release of stress hor ones Ans>. Aṃygdala
  2. This is an egg-shaped structure involved in sensory organ and otor co ṃṃ and processing. All sensory syste s except for the olfaction process through the thala us, which is responsible for processing all external infor- ation Ans>. Thalaṃus
  3. A group of structures involved in voluntary otor ove ents, cogni- tion, and e otion. ove ent disorders include Parkinson's disease, obses- sive-co pulsive disorder (OCD), and Tourette syndro e. Ans>. Basal ganglia

10 / they ay expe- rience anxiety or even schizophrenia. So e eds use this neurotrans itters benefits to help people sleep for edical procedures. Ans>. Gaba

  1. a also a onoa ine neurotrans itter and I serve any functions in the hu an body. Do you re e ber learning about flight, fight, or fright? That's e, in excess. A little of e can get you up off the couch and have you alert, oriented, and ready to take on life's challenges. I can really help with focus and productivity which is why you see e with a cup of coffee. Ans>. Norepinephrine
  2. too uch can cause antsy, nervous, and affect your ability to focus Ans>. Nor- epinephrine
  3. one of the key neurotrans itters that psychotropic drugs target. Within the central nervous syste , I affect arousal, otivation, attention, learning, and RE sleep. I work within the parasy pathetic nervous syste too. I can ake you sweat and salivate.

11 / Ans>. Acetylcholine

  1. Substances that block e can paralyze you because I a the link between the brain and uscles. When there's not enough of e, I can be involved in Alzhei er's and Parkinson's disease. Increase e, and I can help with sy pto s, but be cautious, because I also have a role in addiction. Dr. Stahl refers to e as "the brain's own nicotine" when he talks about y role in addiction. Ans>. acetylcholine
  2. I help to regulate ood. I've been called the "happy hor one," but actually I a not a hor one at all; I a a onoa ine neurotrans itter. Your body synthesizes e naturally fro tryptophan. I help to regulate sleep, arousal, libido, aggression, and pain perception. Ans>. serotonin ( 5HT )
  3. I a one of the key ona ine neurotrans itters that regulate ood. I a associated with executive function, your ability to perfor well, be organized, and all those good things including e otional intelligence. That's when I' working hard in the prefrontal cortex. I' also essential to your ove ent and coordination. Being balanced is very i portant to e; too

13 / e ory, learning, and neural plasticity. I also work to relay sensory infor ation and regulate spinal and otor reflexes. Ans>. glutaṃate

  1. When y levels are too high, I've been associated with schizophrenia, epilepsy, and ania. Ans>. glutaṃate
  2. A group of structures involved in voluntary otor ove ents, cogni- tion, and e otion. ove ent disorders include Parkinson's disease, obses- sive-co pulsive disorder (OCD), and Tourette syndro e. The striatu is a group of structures that includes the caudate, puta en, and nucleus accu - bens. The dorsal striatu contains the caudate nucleus and the puta en. The ventral striatu contains the nucleus accu bens. Both are involved in facilitating voluntary ove ent. Ans>. Basal Ganglia
  3. This is an egg-shaped structure involved in sensory organ and otor co ṃṃ and processing. All sensory syste s except for the olfaction process through this, which is responsible for processing all external infor ation. Has been associated with sy pto s related to schizophrenia and post-trau atic stress

14 / disorder (PTSD). Ans>. thalaṃus

  1. This is involved in co plex otor actions and linkage of cognition to otor actions. It is the ain input area for the basal ganglia and is activated when anticipating or engaging in pleasure. Ans>. Dorsal Striatuṃ
  2. This controls the co ṃṃ unication between the two brain he ispheres. Is involved in attention, i pulse control, and e otion regulation. It integrates

16 / e otional control. Trau atic brain in- juries can result in personality changes, difficulty controlling e otions, and other cognitive functions. Ans>. Frontal Lobes

  1. The iddle part of the brain, responsible for proprioception, is the ho e of the so atic senses. This part of the brain helps a person to identify spatial relationships, interpret pain and touch in the body, and identify and give eaning to objects. Da age to the anterior portion of this lobe ay cause asterogenesis, the loss of ability to recognize objects via the sense of touch. This ay be experienced by patients with post cerebral vascular accidents. Ans>. parietal lobe
  2. This separates the frontal lobe fro the parietal lobe. Ans>. Central Sulcus
  3. It is the working area of the brain and the focus of psychiatry and neurology. Is associated with learning. Changes in this atter are linked to psychiatric diagnoses including Alzhei er's disease, schizophrenia, and ajor depressive disorder. Ans>. Gray ṃatter
  4. are che icals released by neurons to send co ṃṃ unication across synap- tic clefts to other neurons. any psychiatric

17 / disorders and client sy pto s occur fro an excess, deficiency, or i balance of this because it can i pact hu an e otion and behavior. Ans>. Neurotransṃitters

  1. I serve any functions in the hu an body. Do you re e ber learning about flight, fight, or fright? That's e, in excess. A little can get you up off the couch and have you alert, oriented, and ready to take on life's challenges.

10 / 11 hor one," but ac- tually I a not a hor one at all; I a a onoa ine neurotrans itter. Your body synthesizes e naturally fro tryptophan. You know that a ino acid in turkey that akes you content and happy after a big turkey eal? That's e, helping you to feel relaxed, co fortable, and less stressed. I help to regulate sleep, arousal, libido, aggression, and pain perception too! That's how I work in edications too. Ans>. Serotonin

  1. one of the key ona ine neurotrans itters that regulate ood. First of all, I a associated with executive function, your ability to perfor well, be organized, and all those good things including e otional intelligence. That's when I' working hard in the prefrontal cortex. I' also essential to your ove ent and coordination. Being balanced is very i portant to e; too uch or too little can cause proble s. When y levels are low you'll lose pleasure, interest, alertness, and even self- confidence. Low levels are also found in clients who have Parkinson's disease. Too uch of e is not always a good thing. I can lead to the hallucinations you see in schizophrenia and psychosis. Ans>. Dopaṃine
  2. I've been referred to as the workhorse of the brain because I can affect al ost every neuron in the brain. I' quite the firecracker. You'll find e working hard all over the brain

10 / 11 affecting energy, e ory, learning, and neural plasticity. I also work to relay sensory infor ation and regulate spinal and otor reflexes. When y levels are too high, I've been associated with schiz-