ONCC Chemotherapy Immunotherapy Certificate
Exam
3 major phases of cell division: - ANS-Interphase
Mitotic phase
Cytokinesis
3 steps of interphase: - ANS-First growth phase (G1)
Synthesis phase (S phase)
Second growth phase (G2)
4 phases of mitosis: - ANS-Prophase
Metaphase
Anaphase
Telophase
Innate immunity: - ANS-Non-specific response, either:
1. Barrier (skin, mucous membranes, flora of skin/gut)
2. Cellular components (phagocytes, natural killer cells, granulocytes, macrophages)
Adaptive immunity: - ANS-Follows innate immunity if unsuccessful. Memory immunity,
including:
1. Humoral immunity (production of antibodies or immunoglobulins)
2. Cell mediated immunity (dependent upon T cells)
3. Regulatory T -cells (prevent autoimmune reactions and limit inflammatory responses)
Define mutations - ANS-Variations in the nucleotide sequence of a gene
3 main goals of treatment: - ANS-Cure
Control
Palliation
Define neoadjuvant therapy - ANS-Treatment is given prior to surgery to shrink the
tumor
Define adjuvant therapy - ANS-Additional cancer treatment given after the primary
treatment to lower the risk that the cancer reoccur
Define conditioning/preparative therapy - ANS-Treatments used to prepare a patient for
stem cell transplantation
2 types of conditioning therapies: - ANS-Myeloablative
Nonmyeloablative
Define dose density - ANS-Drug dose per unit of time
