Oral Mucosal Lesions: Diagnosis and Management, Exercises of Dentistry

A range of oral mucosal lesions, including leukodema, lichen planus, white spongy nevus, hairy leukoplakia, nicotine stomatitis, and more. It provides information on the clinical features, histological characteristics, and potential causes of these conditions. The document aims to help healthcare professionals accurately diagnose and effectively manage these common oral mucosal disorders. It covers a wide variety of white, red, and mixed lesions that can occur in the oral cavity, providing a comprehensive overview of the topic. The information presented can be valuable for students, clinicians, and researchers interested in understanding and addressing oral mucosal pathologies.

Typology: Exercises

2023/2024

Available from 08/26/2024

DR.dent
DR.dent 🇪🇬

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Choose the correct answer
The white appearance of leukodema is due to ………………………….
(A) Hyperkeratosis
(B) Reduced vascular supply
(C) Dyskeratosis
(D) Hydropic change of keratinocytes
Lichen planus is a/an ……………..
(A) Immunologic defect
(B) Malnutritional disease
(C) Infectious lesion
(D) Hereditary disorder
White interlacing lines (striae of Wickham) on the buccal mucosa are characteristic clinical
features of.............................
(A) Frictional keratosis
(B) Lichen planus
(C) Thermal burn
(D) Follicular keratosis
A histological sample of a bilateral white buccal mucosa lesion revealed a hyperkeratotic
epithelium with basal cell destruction. The epithelium was supported by connective tissue
containing a sub-epithelial dense lymphocytic infiltrate. This lesion is most likely to be ……
(A) Hairy leukoplakia
(B) Leukodema
(C) White spongy nevus
(D) Lichen planus
Nine years old boy has bilateral white thickening of his buccal mucosa that extends into the
vestibules. The lesions have been present since birth. His brother also has similar lesions.
Which of the following is suggested?
(A) Lichen planus
(B) Lupus erythrematosis
(C) White spongy nevus
(D) Hairy leukoplakia
A white palate with occasional red spots in a pipe smoker mouth is called …………………………
(A) Sore mouth
(B) Chronic hyperplastic candidiasis
(C) Nicotine stomatitis
(D) Thermal burn
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Choose the correct answer

The white appearance of leukodema is due to ………………………….

(A) Hyperkeratosis (B) Reduced vascular supply (C) Dyskeratosis (D) Hydropic change of keratinocytes Lichen planus is a/an ……………..

(A) Immunologic defect (B) Malnutritional disease (C) Infectious lesion (D) Hereditary disorder White interlacing lines (striae of Wickham) on the buccal mucosa are characteristic clinical features of.............................

(A) Frictional keratosis (B) Lichen planus (C) Thermal burn (D) Follicular keratosis

A histological sample of a bilateral white buccal mucosa lesion revealed a hyperkeratotic epithelium with basal cell destruction. The epithelium was supported by connective tissue containing a sub-epithelial dense lymphocytic infiltrate. This lesion is most likely to be ……

(A) Hairy leukoplakia (B) Leukodema (C) White spongy nevus (D) Lichen planus

Nine years old boy has bilateral white thickening of his buccal mucosa that extends into the vestibules. The lesions have been present since birth. His brother also has similar lesions. Which of the following is suggested?

(A) Lichen planus (B) Lupus erythrematosis (C) White spongy nevus (D) Hairy leukoplakia

A white palate with occasional red spots in a pipe smoker mouth is called …………………………

(A) Sore mouth (B) Chronic hyperplastic candidiasis (C) Nicotine stomatitis (D) Thermal burn

Microscopic feature of a lesion of the buccal mucosa include epithelial cells with hyperchromatic and pleomorphic nuclei with abnormal mitotic figures at all levels in the epithelium. The basement membrane is intact. The lesion is most likely to be ………………….

(A) Focal hyperkeratosis (B) Leukoplakia (C) Erythroplakia (D) Carcinoma in situ

A patient present with small yellow spots, present bilaterally on buccal mucosa opposite to posterior teeth without any associated complaint. Most probable diagnosis of the condition is

(A) Fordyce's granules (B) Ectopic lymphoid tissue (C) HBID (D) Frictional keratosis

All of the following can present with bilateral buccal mucous white lesion except …………

(A) White spongy nevus (B) Leukodema (C) Hereditary benign intra-epithelial dyskeratosis (D) Frictional keratosis

Butterfly rash across the face is associated with …………………………

(A) Follicular keratosis (B) Systemic lupus erythrematosis (C) Hereditary benign intra-epithelial dyskeratosis (D) Lichen planus

Most common intraoral mucosal chemical burn ……………………..

(A) Drug hypersensitivity reaction (B) Caustic materials used during restorative treatment (C) Aspirin burn (D) Dentifrices induced

Lichenoid lesions ……………………………..

(A) Drug hypersensitivity reaction (B) Autoimmune disease (C) Mucocutaneous lesion (D) Liquefaction degeneration of basal cells

Fordyce’s granules is heterotopic collection of …………………. in oral cavity

(a) Sweat glands (b) Salivary glands (c) Hair follicles (d) Sebaceous glands

The most common intra-oral site of follicular keratosis (Darier’s disease) is ……….

(a) Buccal mucosa and tongue (b) Hard palate and attached gingiva (c) Floor of the mouth (d) Upper and lower lips

Which one of the following isn’t considered as a hereditary white lesion?

(a) Leukoedema (b) Follicular keratosis (c) Oral submucous fibrosis (d) White spongy nevus

The rarely seen clinical form of lichen planus is the ……………………………. form

(a) Reticular (b) Plaque (c) Erosive (d) Bullous

The most common clinical form of lichen planus is the……………………………. form

(a) Reticular (b) Plaque (c) Erosive (d) Bullous

The premalignant form of lichen planus is the……………………………. form

(a) Reticular (b) Plaque (c) Erosive (d) Bullous

Suprabasal clefts containing acantholytic cells characterize …………………..

(a) Frictional keratosis (b) Follicular keratosis (c) Oral submucous fibrosis (d) Oral hairy leukoplakia

The predominant cell in the subepithelial lymphocytic band is ……………..

(a) B lymphocytes (b) Cytotoxic T lymphocytes (c) Helper T lymphocytes (d) Plasma cells

Microscopically, the diagnostic feature of lichen planus is …………………………………..

(a) Subepithelial lymphocytic band (b) Liquefactive degeneration of basal cells (c) Eosinophilic band (d) Subepithelial bullae

The corresponding figure most likely represents……………………

(a) Acantholysis (b) Acanthosis (c) Intraepithelial dyskeratosis (d) hyperkeratosis

The lesion in the corresponding figure could be diagnosed as ……………………………………

(a) leukodema (b) White spongy nevus (c) leukoplakia (d) HBID

The corresponding figures could represents the microscopical features of …………………………………………

(a) leukoplakia (b) HBID (c) Leukodema (d) Familial folded gingivostomatitis

Which one of the following white lesions reveals ocular white plaques?

(a) HBID (b) Follicular keratosis (c) Darier’s disease (d) White spongy nevus

During oral examination of a 57 year old man, a large keratotic patch that covers the entire palate is noted. Some red spots are also seen in the patch. The patient most likely is a:

A. Pipe smoker B. Cigarette smoker C. Snuff chewer D. Tobacco chewer

Read and match

  1. White spongy nevus A.
  2. Leukodema B. Systemic manifestations
  3. Lichen planus C. Epstein’s Barr virus
  4. Fordyce’s granules D. Hydropic degeneration and folded hyperkeratosis
  5. Mucosal burn E. Spontaneous regression after removal of the stimulus
  6. Hereditary benign intraepithelial dyskeratosis F. Palatal white papules with red dots
  7. Darier’s disease G. Liquefaction degeneration of basal cells
  8. Frictional keratosis H. Bilateral white plaques on conjunctiva
  9. Lupus erythrematosis I. Coagulative necrosis at the surface
  10. Ectopic lymphoid tissue J. Disappear upon stretching
  11. Nicotine stomatitis K. Ectopic sebaceous glands
  12. Oral hairy leukoplakia L. Non epithelial yellowish white lesion

M. Affecting intraoral keratinized mucosa with skin and nails manifestations

Tick the following sentences with True () or false (X )

Nicotine stomatitis has a high malignant potential. (.……)

Basal cells are the target of the autoimmune reaction in lichen planus. (.……)

Acantholysis means increased thickness of the spinous cell layer. (.……)

However, oral submucous fibrosis shows marked epithelial atrophy, it appears clinically as a white plaque.

(.……)

The white slough of mucosal burns can be rubbed off and is attributed to the surface coagulative necrosis

(.……)

When the entire thickness of epithelium shows signs of epithelial dysplasia without invasion, the term carcinoma in situ is used. (......)

Epstein's Barr virus is implicated in the pathogenesis of oral hairy leukoplakia. (.……)

Discoid Lupus erythrematosis is a systemic mucocutaneous autoimmune disease (…….)

Actinic cheilitis is a premalignant lesion results from prolonged exposure to UV light of the sun (……)

In actinic cheilitis, UV light transforms collagen fibers to elastin. Therefore, the underlying connective tissue reveals marked acellular basophilia (……….)