Pathophysiology Case Studies: Appendicitis and Cystitis, Exams of Nursing

Two case studies, one focusing on acute appendicitis and the other on cystitis. It explores the pathophysiology of each condition, analyzing the sequence of pain in appendicitis and the causes of leukocytosis and fever. The document also discusses the symptoms, causes, and preventative measures for cystitis, highlighting the importance of timely treatment to avoid complications like kidney infections. A valuable learning resource for students of medicine and healthcare professionals.

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2024/2025

Available from 01/22/2025

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PATHO WEEK 5 DISCUSSION.
Ms. F, 48 years old, has been admitted to the hospital with severe abdominal pain. Earlier that
day she had generalized abdominal pain, followed by a severe pain in the lower right quadrant of
her abdomen, accompanied by nausea and vomiting. That evening she was feeling slightly
improved, and the pain seemed to subside somewhat. Later that night, severe, steady abdominal
pain developed, with vomiting. A friend took her to the hospital, where examination
demonstrated lower right quadrant tenderness and mild abdominal rigidity. Fever and
leukocytosis indicated infection. A diagnosis of acute appendicitis, with possible perforation, was
indicated, with immediate surgery.
WHY IS THE SEQUENCE OF PAIN (LOCATION AND TYPE OF PAIN)
SIGNIFICANT IN THE DIAGNOSIS OF ACUTE APPENDICITIS?
DESCRIBE THE RATIONAL FOR EACH TYPE OF PAIN. DOES THIS
SEQUENCE CONFIRM THE DIAGNOSIS?
The patient’s sequence of pain is within the signs and symptoms of many
abdominal disorders. Appendicitis is known to manifest without acute symptoms
initially, Mrs. F abdominal pain combined with nausea and vomiting could be less
than anything of importance. Generally, the pain starts as a colicky periumbilical
pain which increases in severity as the inflamed appendix is distended. Then the
pain radiates to the lower right quadrant of the abdomen where deep localized
tenderness is present upon palpation. Pain in the lower right quadrant is related
to the inflamed stretched tissues of the appendix. After appendix ruptures pain at
this point decreases as the appendix spills its contents into the peritoneal cavity
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PATHO WEEK 5 DISCUSSION.

Ms. F, 48 years old, has been admitted to the hospital with severe abdominal pain. Earlier that day she had generalized abdominal pain, followed by a severe pain in the lower right quadrant of her abdomen, accompanied by nausea and vomiting. That evening she was feeling slightly improved, and the pain seemed to subside somewhat. Later that night, severe, steady abdominal pain developed, with vomiting. A friend took her to the hospital, where examination demonstrated lower right quadrant tenderness and mild abdominal rigidity. Fever and leukocytosis indicated infection. A diagnosis of acute appendicitis, with possible perforation, was indicated, with immediate surgery.

WHY IS THE SEQUENCE OF PAIN (LOCATION AND TYPE OF PAIN)

SIGNIFICANT IN THE DIAGNOSIS OF ACUTE APPENDICITIS?

DESCRIBE THE RATIONAL FOR EACH TYPE OF PAIN. DOES THIS

SEQUENCE CONFIRM THE DIAGNOSIS?

The patient’s sequence of pain is within the signs and symptoms of many abdominal disorders. Appendicitis is known to manifest without acute symptoms initially, Mrs. F abdominal pain combined with nausea and vomiting could be less than anything of importance. Generally, the pain starts as a colicky periumbilical pain which increases in severity as the inflamed appendix is distended. Then the pain radiates to the lower right quadrant of the abdomen where deep localized tenderness is present upon palpation. Pain in the lower right quadrant is related to the inflamed stretched tissues of the appendix. After appendix ruptures pain at this point decreases as the appendix spills its contents into the peritoneal cavity

creating peritonitis which then exacerbates pain again due to spreading of infection. Appendicitis is a common etiology of abdominal pain, caused by acute inflammation of the appendix, and occurs in approximately 10% of the population. Abdominal pain is a common presenting complaint for patients seeking care at emergency departments. Untreated appendicitis can lead to perforation of the appendix, which typically occurs within 24 to 36 hours of the onset of symptoms.

  1. Cystitis is inflammation of the bladder. The cause of cystitis is a urinary tract infection, a UTI happens when bacteria enter the bladder or urethra and begin to multiply. Women are more susceptible to getting UTI’s. Cystitis is a lot more common in women than men, the anus (back passage, where bacteria from your bowl can collect) is closer to the urethra in women and the urethra is much shorter (Mayo Clinic, 2019).
  2. Preventatives measures of cystitis include making sure you’re drinking plenty of fluids, urinate frequently, wipe from front to back after a bowel movement, take showers rather than tub baths, empty your bladder as soon as possible after intercourse, avoid drinking alcohol, coffee, or citrus juices, avoid wearing tight jeans and avoid wearing cotton underwear.
  1. Signs and symptoms that indicate cystitis include a strong persistent urge to urinate, burning sensation when urinating, blood in the urine, cloudy or strong-smelling urine, pelvic discomfort, feeling of pressure in the lower abdomen, low-grade fever, nausea, vomiting, back or side pain and chills (Mayo Clinic, 2019).
  2. Potential problems that can occur if you don’t adhere to the treatment prescribed is if left untreated you could get a kidney infection also called pyelonephritis. You also may continue to experience symptoms such as burning when you urinate, pelvic pain, fever, and pressure in lower abdomen (Mayo Clinic, 2019). References “Preventing Cystitis.” HSE.ie , Retrieved from https//www.hse.ie/eng/health/az/b/bladder- infection/preventing- cystitis.html. Hubert, R. & VanMeter, K. (2018). Gould's pathophysiology for the health professions (6th ed.). Elsevier Epidermoid Cysts – Symptoms and Causes – Mayo Clinic (April 7 th, 2019). https://www.mayoclinic.org/diseases-conditions/epidermoid-cysts/symptoms-causes/syc- 20352701