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A concise overview of endocrine system pathophysiology, focusing on hormone actions, imbalances, and related diseases such as hyperthyroidism, hypothyroidism, addison's disease, cushing's syndrome, and diabetes mellitus. It includes key concepts, diagnostic approaches, and treatment options, presented in a question-and-answer format suitable for study and review. The material covers hormone secretion mechanisms, adrenal gland functions, and the pathophysiology of diabetes, including dka and hhs. It also addresses microvascular and macrovascular complications of diabetes, offering a structured approach to understanding these complex topics. Useful for medical and nursing students.
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endocrine, paracrine, autocrine - โ๏ธ endocrine: hormones are released into circulation to act on a target organ paracrine: hormones act locally on cells close to where they are released autocrine: hormones produce a biologic action on the cell that released them transport carriers on which hormones? - โ๏ธ peptide and protein hormones: unattached steroid hormones: carrier protein what are the different structural types of hormones? - โ๏ธ amines and amino acids peptides and proteins steroids, made from cholesterol function of hypothalamus - โ๏ธ link between NS and endocrine regulates homeostasis, body temp, hunger, behavior. emotion, pain produces releasing hormones which stimulate pituitary to release stimulating hormones What is the role of the pituitary gland? - โ๏ธ "master gland," stimulates target organs to secrete their hormones anterior pituitary hormones - โ๏ธ GH, ACTH, TSH, FSH, LH, prolactin posterior pituitary hormones - โ๏ธ ADH and oxytocin ways hormones can be oversecreted - โ๏ธ 1. target gland over-secretes due to pathology
โ๏ธ 1. congenital or acquired disorder of target gland
aldosterone function - โ๏ธ triggers reabsorption of sodium and secretion of K in kidneys secretion caused by RAA or hyperkalemia aldosterone deficiency causes - โ๏ธ 1. lack of RAA stimulus from kidney disease or drugs
โ๏ธ 1. latrogenic from long-term steroid treatment
oral antidiabetics - โ๏ธ WRITE DOWN insulin hypoglycemia - โ๏ธ <60 blood sugar, cognitive problems side effect of insulin therapy treat with 15-20 g glucose